Detecting past changes of effective population size
International audience Understanding and predicting population abundance is a major challenge confronting scientists. Several genetic models have been developed using microsatellite markers to estimate the present and ancestral effective population sizes. However, to get an overview on the evolution...
Published in: | Evolutionary Applications |
---|---|
Main Authors: | , |
Other Authors: | , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
HAL CCSD
2014
|
Subjects: | |
Online Access: | https://hal.inrae.fr/hal-02641586 https://hal.inrae.fr/hal-02641586/document https://hal.inrae.fr/hal-02641586/file/Nikolic_et_al-2014-Evolutionary_Applications_1.pdf https://doi.org/10.1111/eva.12170 |
id |
ftunivnantes:oai:HAL:hal-02641586v1 |
---|---|
record_format |
openpolar |
spelling |
ftunivnantes:oai:HAL:hal-02641586v1 2023-05-15T15:31:32+02:00 Detecting past changes of effective population size Nikolic, Natacha Chevalet, Claude Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER) Génétique Physiologie et Systèmes d'Elevage (GenPhySE ) Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT) Institut National Polytechnique (Toulouse) (Toulouse INP) Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP) Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-École nationale supérieure agronomique de Toulouse ENSAT Laboratoire de Genetique Cellulaire at INRA (Toulouse) 2014 https://hal.inrae.fr/hal-02641586 https://hal.inrae.fr/hal-02641586/document https://hal.inrae.fr/hal-02641586/file/Nikolic_et_al-2014-Evolutionary_Applications_1.pdf https://doi.org/10.1111/eva.12170 en eng HAL CCSD Blackwell info:eu-repo/semantics/altIdentifier/doi/10.1111/eva.12170 info:eu-repo/semantics/altIdentifier/pmid/25067949 hal-02641586 https://hal.inrae.fr/hal-02641586 https://hal.inrae.fr/hal-02641586/document https://hal.inrae.fr/hal-02641586/file/Nikolic_et_al-2014-Evolutionary_Applications_1.pdf doi:10.1111/eva.12170 PRODINRA: 274834 PUBMED: 25067949 WOS: 000338039600005 http://creativecommons.org/licenses/by/ info:eu-repo/semantics/OpenAccess ISSN: 1752-4563 EISSN: 1752-4571 Evolutionary Applications https://hal.inrae.fr/hal-02641586 Evolutionary Applications, 2014, 7 (6), pp.663-681. ⟨10.1111/eva.12170⟩ Atlantic salmon effective population size past demography microsatellites [SDV]Life Sciences [q-bio] [INFO]Computer Science [cs] info:eu-repo/semantics/article Journal articles 2014 ftunivnantes https://doi.org/10.1111/eva.12170 2023-02-22T06:34:06Z International audience Understanding and predicting population abundance is a major challenge confronting scientists. Several genetic models have been developed using microsatellite markers to estimate the present and ancestral effective population sizes. However, to get an overview on the evolution of population requires that past fluctuation of population size be traceable. To address the question, we developed a new model estimating the past changes of effective population size from microsatellite by resolving coalescence theory and using approximate likelihoods in a Monte Carlo Markov Chain approach. The efficiency of the model and its sensitivity to gene flow and to assumptions on the mutational process were checked using simulated data and analysis. The model was found especially useful to provide evidence of transient changes of population size in the past. The times at which some past demographic events cannot be detected because they are too ancient and the risk that gene flow may suggest the false detection of a bottleneck are discussed considering the distribution of coalescence times. The method was applied on real data sets from several Atlantic salmon populations. The method called VarEff (Variation of Effective size) was implemented in the R package VarEff and is made available at https://qgsp.jouy.inra.fr and at http://cran.r-project.org/web/packages/VarEff. Article in Journal/Newspaper Atlantic salmon Université de Nantes: HAL-UNIV-NANTES Evolutionary Applications 7 6 663 681 |
institution |
Open Polar |
collection |
Université de Nantes: HAL-UNIV-NANTES |
op_collection_id |
ftunivnantes |
language |
English |
topic |
Atlantic salmon effective population size past demography microsatellites [SDV]Life Sciences [q-bio] [INFO]Computer Science [cs] |
spellingShingle |
Atlantic salmon effective population size past demography microsatellites [SDV]Life Sciences [q-bio] [INFO]Computer Science [cs] Nikolic, Natacha Chevalet, Claude Detecting past changes of effective population size |
topic_facet |
Atlantic salmon effective population size past demography microsatellites [SDV]Life Sciences [q-bio] [INFO]Computer Science [cs] |
description |
International audience Understanding and predicting population abundance is a major challenge confronting scientists. Several genetic models have been developed using microsatellite markers to estimate the present and ancestral effective population sizes. However, to get an overview on the evolution of population requires that past fluctuation of population size be traceable. To address the question, we developed a new model estimating the past changes of effective population size from microsatellite by resolving coalescence theory and using approximate likelihoods in a Monte Carlo Markov Chain approach. The efficiency of the model and its sensitivity to gene flow and to assumptions on the mutational process were checked using simulated data and analysis. The model was found especially useful to provide evidence of transient changes of population size in the past. The times at which some past demographic events cannot be detected because they are too ancient and the risk that gene flow may suggest the false detection of a bottleneck are discussed considering the distribution of coalescence times. The method was applied on real data sets from several Atlantic salmon populations. The method called VarEff (Variation of Effective size) was implemented in the R package VarEff and is made available at https://qgsp.jouy.inra.fr and at http://cran.r-project.org/web/packages/VarEff. |
author2 |
Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER) Génétique Physiologie et Systèmes d'Elevage (GenPhySE ) Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT) Institut National Polytechnique (Toulouse) (Toulouse INP) Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP) Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-École nationale supérieure agronomique de Toulouse ENSAT Laboratoire de Genetique Cellulaire at INRA (Toulouse) |
format |
Article in Journal/Newspaper |
author |
Nikolic, Natacha Chevalet, Claude |
author_facet |
Nikolic, Natacha Chevalet, Claude |
author_sort |
Nikolic, Natacha |
title |
Detecting past changes of effective population size |
title_short |
Detecting past changes of effective population size |
title_full |
Detecting past changes of effective population size |
title_fullStr |
Detecting past changes of effective population size |
title_full_unstemmed |
Detecting past changes of effective population size |
title_sort |
detecting past changes of effective population size |
publisher |
HAL CCSD |
publishDate |
2014 |
url |
https://hal.inrae.fr/hal-02641586 https://hal.inrae.fr/hal-02641586/document https://hal.inrae.fr/hal-02641586/file/Nikolic_et_al-2014-Evolutionary_Applications_1.pdf https://doi.org/10.1111/eva.12170 |
genre |
Atlantic salmon |
genre_facet |
Atlantic salmon |
op_source |
ISSN: 1752-4563 EISSN: 1752-4571 Evolutionary Applications https://hal.inrae.fr/hal-02641586 Evolutionary Applications, 2014, 7 (6), pp.663-681. ⟨10.1111/eva.12170⟩ |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1111/eva.12170 info:eu-repo/semantics/altIdentifier/pmid/25067949 hal-02641586 https://hal.inrae.fr/hal-02641586 https://hal.inrae.fr/hal-02641586/document https://hal.inrae.fr/hal-02641586/file/Nikolic_et_al-2014-Evolutionary_Applications_1.pdf doi:10.1111/eva.12170 PRODINRA: 274834 PUBMED: 25067949 WOS: 000338039600005 |
op_rights |
http://creativecommons.org/licenses/by/ info:eu-repo/semantics/OpenAccess |
op_doi |
https://doi.org/10.1111/eva.12170 |
container_title |
Evolutionary Applications |
container_volume |
7 |
container_issue |
6 |
container_start_page |
663 |
op_container_end_page |
681 |
_version_ |
1766362055603912704 |