Polychlorinated biphenyls (PCBs) and their hydroxylated metabolites (OH-PCBs) in harbor seal () livers from San Francisco Bay, California and Gulf of Maine
International audience Bioaccumulation of endocrine disruptors in marine mammals positioned at the top of the food chain is of toxicological concern. Stranded four pup and ten adult harbor seal () livers were collected from San Francisco Bay and the Gulf of Maine and analyzed for polychlorinated bip...
Published in: | Marine Environmental Research |
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Online Access: | https://hal.archives-ouvertes.fr/hal-00563064 https://hal.archives-ouvertes.fr/hal-00563064/document https://hal.archives-ouvertes.fr/hal-00563064/file/PEER_stage2_10.1016%252Fj.marenvres.2008.12.003.pdf https://doi.org/10.1016/j.marenvres.2008.12.003 |
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ftunivnantes:oai:HAL:hal-00563064v1 2023-05-15T15:41:54+02:00 Polychlorinated biphenyls (PCBs) and their hydroxylated metabolites (OH-PCBs) in harbor seal () livers from San Francisco Bay, California and Gulf of Maine Park, June-Soo Kalantzi, Olga Ioanna Kopec, Dianne Petreas, Myrto Department of Toxic Substances Control California Environmental Protection Agency Department of Biological Sciences Portland University of Southern Maine 2009-02-20 https://hal.archives-ouvertes.fr/hal-00563064 https://hal.archives-ouvertes.fr/hal-00563064/document https://hal.archives-ouvertes.fr/hal-00563064/file/PEER_stage2_10.1016%252Fj.marenvres.2008.12.003.pdf https://doi.org/10.1016/j.marenvres.2008.12.003 en eng HAL CCSD Elsevier science info:eu-repo/semantics/altIdentifier/doi/10.1016/j.marenvres.2008.12.003 hal-00563064 https://hal.archives-ouvertes.fr/hal-00563064 https://hal.archives-ouvertes.fr/hal-00563064/document https://hal.archives-ouvertes.fr/hal-00563064/file/PEER_stage2_10.1016%252Fj.marenvres.2008.12.003.pdf doi:10.1016/j.marenvres.2008.12.003 info:eu-repo/semantics/OpenAccess ISSN: 0141-1136 EISSN: 1879-0291 Marine Environmental Research https://hal.archives-ouvertes.fr/hal-00563064 Marine Environmental Research, 2009, 67 (3), pp.129. ⟨10.1016/j.marenvres.2008.12.003⟩ Hydroxylated PCB metabolites Polychlorinated biphenyls Harbor seal liver San Francisco Bay Gulf of Maine info:eu-repo/semantics/article Journal articles 2009 ftunivnantes https://doi.org/10.1016/j.marenvres.2008.12.003 2022-12-13T23:44:29Z International audience Bioaccumulation of endocrine disruptors in marine mammals positioned at the top of the food chain is of toxicological concern. Stranded four pup and ten adult harbor seal () livers were collected from San Francisco Bay and the Gulf of Maine and analyzed for polychlorinated biphenyls (PCBs) and their hydroxylated metabolites (OH-PCBs). We used GC-ECD and GC-NCI/MS to investigate the presence of 28 PCBs and 8 OH-PCB metabolites, respectively. ΣPCB concentrations (di- to octa-CBs) ranged from 1.81 to 35.9 μg/g lipid with a median of 6.53 for the seal pups and 2.31 to 249 μg/g lipid with a median of 28.9 for the adult seals. ΣOH-PCB concentrations (penta- to hepta-OH-PCBs) ranged from 0.02 to 0.69 μg/g lipid with a median of 0.04 for the adult seals, i.e., at much lower concentrations than those for PCBs. Ratios of OH-PCBs to PCBs (0.24% on average) were comparable to those in beluga whale, but were lower than ratios in human livers. The OH-PCB profiles were slightly different between SFB and GOM seal livers although similar PCB congener patterns were observed. Generally, 4-OH-CB107 was found predominantly in seal livers and was the only OH-PCB detectable in most of seal pup livers. This study provides information on OH-PCBs in seals, adding to the scarce exposure data for these chemicals. Article in Journal/Newspaper Beluga Beluga whale Beluga* harbor seal Université de Nantes: HAL-UNIV-NANTES Marine Environmental Research 67 3 129 135 |
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Open Polar |
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Université de Nantes: HAL-UNIV-NANTES |
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ftunivnantes |
language |
English |
topic |
Hydroxylated PCB metabolites Polychlorinated biphenyls Harbor seal liver San Francisco Bay Gulf of Maine |
spellingShingle |
Hydroxylated PCB metabolites Polychlorinated biphenyls Harbor seal liver San Francisco Bay Gulf of Maine Park, June-Soo Kalantzi, Olga Ioanna Kopec, Dianne Petreas, Myrto Polychlorinated biphenyls (PCBs) and their hydroxylated metabolites (OH-PCBs) in harbor seal () livers from San Francisco Bay, California and Gulf of Maine |
topic_facet |
Hydroxylated PCB metabolites Polychlorinated biphenyls Harbor seal liver San Francisco Bay Gulf of Maine |
description |
International audience Bioaccumulation of endocrine disruptors in marine mammals positioned at the top of the food chain is of toxicological concern. Stranded four pup and ten adult harbor seal () livers were collected from San Francisco Bay and the Gulf of Maine and analyzed for polychlorinated biphenyls (PCBs) and their hydroxylated metabolites (OH-PCBs). We used GC-ECD and GC-NCI/MS to investigate the presence of 28 PCBs and 8 OH-PCB metabolites, respectively. ΣPCB concentrations (di- to octa-CBs) ranged from 1.81 to 35.9 μg/g lipid with a median of 6.53 for the seal pups and 2.31 to 249 μg/g lipid with a median of 28.9 for the adult seals. ΣOH-PCB concentrations (penta- to hepta-OH-PCBs) ranged from 0.02 to 0.69 μg/g lipid with a median of 0.04 for the adult seals, i.e., at much lower concentrations than those for PCBs. Ratios of OH-PCBs to PCBs (0.24% on average) were comparable to those in beluga whale, but were lower than ratios in human livers. The OH-PCB profiles were slightly different between SFB and GOM seal livers although similar PCB congener patterns were observed. Generally, 4-OH-CB107 was found predominantly in seal livers and was the only OH-PCB detectable in most of seal pup livers. This study provides information on OH-PCBs in seals, adding to the scarce exposure data for these chemicals. |
author2 |
Department of Toxic Substances Control California Environmental Protection Agency Department of Biological Sciences Portland University of Southern Maine |
format |
Article in Journal/Newspaper |
author |
Park, June-Soo Kalantzi, Olga Ioanna Kopec, Dianne Petreas, Myrto |
author_facet |
Park, June-Soo Kalantzi, Olga Ioanna Kopec, Dianne Petreas, Myrto |
author_sort |
Park, June-Soo |
title |
Polychlorinated biphenyls (PCBs) and their hydroxylated metabolites (OH-PCBs) in harbor seal () livers from San Francisco Bay, California and Gulf of Maine |
title_short |
Polychlorinated biphenyls (PCBs) and their hydroxylated metabolites (OH-PCBs) in harbor seal () livers from San Francisco Bay, California and Gulf of Maine |
title_full |
Polychlorinated biphenyls (PCBs) and their hydroxylated metabolites (OH-PCBs) in harbor seal () livers from San Francisco Bay, California and Gulf of Maine |
title_fullStr |
Polychlorinated biphenyls (PCBs) and their hydroxylated metabolites (OH-PCBs) in harbor seal () livers from San Francisco Bay, California and Gulf of Maine |
title_full_unstemmed |
Polychlorinated biphenyls (PCBs) and their hydroxylated metabolites (OH-PCBs) in harbor seal () livers from San Francisco Bay, California and Gulf of Maine |
title_sort |
polychlorinated biphenyls (pcbs) and their hydroxylated metabolites (oh-pcbs) in harbor seal () livers from san francisco bay, california and gulf of maine |
publisher |
HAL CCSD |
publishDate |
2009 |
url |
https://hal.archives-ouvertes.fr/hal-00563064 https://hal.archives-ouvertes.fr/hal-00563064/document https://hal.archives-ouvertes.fr/hal-00563064/file/PEER_stage2_10.1016%252Fj.marenvres.2008.12.003.pdf https://doi.org/10.1016/j.marenvres.2008.12.003 |
genre |
Beluga Beluga whale Beluga* harbor seal |
genre_facet |
Beluga Beluga whale Beluga* harbor seal |
op_source |
ISSN: 0141-1136 EISSN: 1879-0291 Marine Environmental Research https://hal.archives-ouvertes.fr/hal-00563064 Marine Environmental Research, 2009, 67 (3), pp.129. ⟨10.1016/j.marenvres.2008.12.003⟩ |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.marenvres.2008.12.003 hal-00563064 https://hal.archives-ouvertes.fr/hal-00563064 https://hal.archives-ouvertes.fr/hal-00563064/document https://hal.archives-ouvertes.fr/hal-00563064/file/PEER_stage2_10.1016%252Fj.marenvres.2008.12.003.pdf doi:10.1016/j.marenvres.2008.12.003 |
op_rights |
info:eu-repo/semantics/OpenAccess |
op_doi |
https://doi.org/10.1016/j.marenvres.2008.12.003 |
container_title |
Marine Environmental Research |
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67 |
container_issue |
3 |
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129 |
op_container_end_page |
135 |
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