How Cadmium could compromise the completion of the European eel's reproductive migration

International audience The European eel (Anguilla anguilla L.) is severely threatened with extinction. Surprisingly, even though their unusual life cycle makes them particularly vulnerable to pollution, the possible contribution of contamination remains especially poorly known. Here we have investig...

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Published in:Environmental Science & Technology
Main Authors: Pierron, Fabien, Baudrimont, Magalie, Dufour, Sylvie, Elie, Pierre, Bossy, Angélique, Baloche, Sylvie, Mesmer-Dudons, Nathalie, Gonzalez, Patrice, Bourdineaud, Jean-Paul, Massabuau, Jean-Charles
Other Authors: Biologie des organismes marins et écosystèmes (BOME), Muséum national d'Histoire naturelle (MNHN)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)
Format: Article in Journal/Newspaper
Language:English
Published: HAL CCSD 2008
Subjects:
Online Access:https://hal.science/hal-00384733
https://doi.org/10.1021/es703127c
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spelling ftunivnantes:oai:HAL:hal-00384733v1 2023-05-15T13:28:01+02:00 How Cadmium could compromise the completion of the European eel's reproductive migration Pierron, Fabien Baudrimont, Magalie Dufour, Sylvie Elie, Pierre Bossy, Angélique Baloche, Sylvie Mesmer-Dudons, Nathalie Gonzalez, Patrice Bourdineaud, Jean-Paul Massabuau, Jean-Charles Biologie des organismes marins et écosystèmes (BOME) Muséum national d'Histoire naturelle (MNHN)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS) 2008 https://hal.science/hal-00384733 https://doi.org/10.1021/es703127c en eng HAL CCSD American Chemical Society info:eu-repo/semantics/altIdentifier/doi/10.1021/es703127c hal-00384733 https://hal.science/hal-00384733 doi:10.1021/es703127c ISSN: 0013-936X EISSN: 1520-5851 Environmental Science and Technology https://hal.science/hal-00384733 Environmental Science and Technology, 2008, 42, pp.4607-4612. ⟨10.1021/es703127c⟩ [SDV.BDLR]Life Sciences [q-bio]/Reproductive Biology [SDV.TOX]Life Sciences [q-bio]/Toxicology [SDV.EE]Life Sciences [q-bio]/Ecology environment info:eu-repo/semantics/article Journal articles 2008 ftunivnantes https://doi.org/10.1021/es703127c 2023-02-08T02:12:26Z International audience The European eel (Anguilla anguilla L.) is severely threatened with extinction. Surprisingly, even though their unusual life cycle makes them particularly vulnerable to pollution, the possible contribution of contamination remains especially poorly known. Here we have investigated the possible effect of cadmium (Cd), a widespread nonessential metal, on eel reproductive capacities. Both control and Cd precontaminated female silver eels were experimentally matured and forced to swim in metal-free conditions to mimic their reproductive migration. Cd pre-exposure was found to strongly stimulate the pituitary−gonad−liver axis of maturing female silver eels leading to early and enhanced vitellogenesis. This was followed by a strong phenomenon of oocyte atresia and eel mortality. These phenomena occurred before oocytes could reach full maturation and were associated with a large entry of both vitellogenin and Cd into the ovaries. Indeed, a redistribution of previously stored cadmium, even from the low Cd levels of control eels, was observed during sexual maturation. Atresia and mortality phenomena were also associated with an overexpression of the pituitary gene encoding the growth hormone, a marker of physiological stress and energy reserves exhaustion. Significantly, these devastating effects of Cd were observed in organisms that presented liver and kidney Cd concentrations still below those observed in eels from Cd contaminated hydrosystems. Our research shows how common levels of cadmium contamination could disrupt endocrine pathways implicated in gonad maturation and subsequently impair reproductive capacity of eel future genitors Article in Journal/Newspaper Anguilla anguilla Université de Nantes: HAL-UNIV-NANTES Environmental Science & Technology 42 12 4607 4612
institution Open Polar
collection Université de Nantes: HAL-UNIV-NANTES
op_collection_id ftunivnantes
language English
topic [SDV.BDLR]Life Sciences [q-bio]/Reproductive Biology
[SDV.TOX]Life Sciences [q-bio]/Toxicology
[SDV.EE]Life Sciences [q-bio]/Ecology
environment
spellingShingle [SDV.BDLR]Life Sciences [q-bio]/Reproductive Biology
[SDV.TOX]Life Sciences [q-bio]/Toxicology
[SDV.EE]Life Sciences [q-bio]/Ecology
environment
Pierron, Fabien
Baudrimont, Magalie
Dufour, Sylvie
Elie, Pierre
Bossy, Angélique
Baloche, Sylvie
Mesmer-Dudons, Nathalie
Gonzalez, Patrice
Bourdineaud, Jean-Paul
Massabuau, Jean-Charles
How Cadmium could compromise the completion of the European eel's reproductive migration
topic_facet [SDV.BDLR]Life Sciences [q-bio]/Reproductive Biology
[SDV.TOX]Life Sciences [q-bio]/Toxicology
[SDV.EE]Life Sciences [q-bio]/Ecology
environment
description International audience The European eel (Anguilla anguilla L.) is severely threatened with extinction. Surprisingly, even though their unusual life cycle makes them particularly vulnerable to pollution, the possible contribution of contamination remains especially poorly known. Here we have investigated the possible effect of cadmium (Cd), a widespread nonessential metal, on eel reproductive capacities. Both control and Cd precontaminated female silver eels were experimentally matured and forced to swim in metal-free conditions to mimic their reproductive migration. Cd pre-exposure was found to strongly stimulate the pituitary−gonad−liver axis of maturing female silver eels leading to early and enhanced vitellogenesis. This was followed by a strong phenomenon of oocyte atresia and eel mortality. These phenomena occurred before oocytes could reach full maturation and were associated with a large entry of both vitellogenin and Cd into the ovaries. Indeed, a redistribution of previously stored cadmium, even from the low Cd levels of control eels, was observed during sexual maturation. Atresia and mortality phenomena were also associated with an overexpression of the pituitary gene encoding the growth hormone, a marker of physiological stress and energy reserves exhaustion. Significantly, these devastating effects of Cd were observed in organisms that presented liver and kidney Cd concentrations still below those observed in eels from Cd contaminated hydrosystems. Our research shows how common levels of cadmium contamination could disrupt endocrine pathways implicated in gonad maturation and subsequently impair reproductive capacity of eel future genitors
author2 Biologie des organismes marins et écosystèmes (BOME)
Muséum national d'Histoire naturelle (MNHN)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)
format Article in Journal/Newspaper
author Pierron, Fabien
Baudrimont, Magalie
Dufour, Sylvie
Elie, Pierre
Bossy, Angélique
Baloche, Sylvie
Mesmer-Dudons, Nathalie
Gonzalez, Patrice
Bourdineaud, Jean-Paul
Massabuau, Jean-Charles
author_facet Pierron, Fabien
Baudrimont, Magalie
Dufour, Sylvie
Elie, Pierre
Bossy, Angélique
Baloche, Sylvie
Mesmer-Dudons, Nathalie
Gonzalez, Patrice
Bourdineaud, Jean-Paul
Massabuau, Jean-Charles
author_sort Pierron, Fabien
title How Cadmium could compromise the completion of the European eel's reproductive migration
title_short How Cadmium could compromise the completion of the European eel's reproductive migration
title_full How Cadmium could compromise the completion of the European eel's reproductive migration
title_fullStr How Cadmium could compromise the completion of the European eel's reproductive migration
title_full_unstemmed How Cadmium could compromise the completion of the European eel's reproductive migration
title_sort how cadmium could compromise the completion of the european eel's reproductive migration
publisher HAL CCSD
publishDate 2008
url https://hal.science/hal-00384733
https://doi.org/10.1021/es703127c
genre Anguilla anguilla
genre_facet Anguilla anguilla
op_source ISSN: 0013-936X
EISSN: 1520-5851
Environmental Science and Technology
https://hal.science/hal-00384733
Environmental Science and Technology, 2008, 42, pp.4607-4612. ⟨10.1021/es703127c⟩
op_relation info:eu-repo/semantics/altIdentifier/doi/10.1021/es703127c
hal-00384733
https://hal.science/hal-00384733
doi:10.1021/es703127c
op_doi https://doi.org/10.1021/es703127c
container_title Environmental Science & Technology
container_volume 42
container_issue 12
container_start_page 4607
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