Accumulation of neurotoxic organochlorines and trace elements in brain of female European eel (Anguilla anguilla)
Xenobiotics such as organochlorine compounds (OCs) and metals have been suggested to play a significant role in the collapse of European eel stocks in the last decades. Several of these pollutants could affect functioning of the nervous system. Still, no information is so far available on levels of...
Published in: | Environmental Toxicology and Pharmacology |
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Language: | English |
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2016
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Online Access: | https://researchportal.unamur.be/en/publications/accumulation-of-neurotoxic-organochlorines-and-trace-elements-in-brain-of-female-european-eel-anguilla-anguilla(d76975ef-73f8-493c-acd3-bf3553010b2f).html https://doi.org/10.1016/j.etap.2016.06.009 http://www.scopus.com/inward/record.url?scp=84976353356&partnerID=8YFLogxK |
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ftunivnamurcrisp:oai:pure.unamur.be:publications/d76975ef-73f8-493c-acd3-bf3553010b2f 2023-05-15T13:28:02+02:00 Accumulation of neurotoxic organochlorines and trace elements in brain of female European eel (Anguilla anguilla) Bonnineau, C. Scaion, D. Lemaire, B. Belpaire, Claude THOMÉ, Jean-Pierre Thonon, M. Leermaker, M. Gao, Y. Debier, C. Silvestre, F. Kestemont, P. Rees, Jean-François 2016-07-01 https://researchportal.unamur.be/en/publications/accumulation-of-neurotoxic-organochlorines-and-trace-elements-in-brain-of-female-european-eel-anguilla-anguilla(d76975ef-73f8-493c-acd3-bf3553010b2f).html https://doi.org/10.1016/j.etap.2016.06.009 http://www.scopus.com/inward/record.url?scp=84976353356&partnerID=8YFLogxK eng eng info:eu-repo/semantics/closedAccess Bonnineau , C , Scaion , D , Lemaire , B , Belpaire , C , THOMÉ , J-P , Thonon , M , Leermaker , M , Gao , Y , Debier , C , Silvestre , F , Kestemont , P & Rees , J-F 2016 , ' Accumulation of neurotoxic organochlorines and trace elements in brain of female European eel (Anguilla anguilla) ' , Environmental Toxicology and Pharmacology , vol. 45 , pp. 346-355 . https://doi.org/10.1016/j.etap.2016.06.009 Brain Eel Mercury Metals Organochlorine pesticides PCBs Toxicology /dk/atira/pure/subjectarea/asjc/3000/3005 /dk/atira/pure/subjectarea/asjc/2300/2307 Health Toxicology and Mutagenesis /dk/atira/pure/subjectarea/asjc/3000/3004 Pharmacology article 2016 ftunivnamurcrisp https://doi.org/10.1016/j.etap.2016.06.009 2020-03-22T10:08:21Z Xenobiotics such as organochlorine compounds (OCs) and metals have been suggested to play a significant role in the collapse of European eel stocks in the last decades. Several of these pollutants could affect functioning of the nervous system. Still, no information is so far available on levels of potentially neurotoxic pollutants in eel brain. In present study, carried out on female eels caught in Belgian rivers and canals, we analyzed brain levels of potentially-neurotoxic trace elements (Ag, Al, As, Cd, Co, Cr, Cu, Fe, Hg, MeHg, Mn, Ni, Pb, Sn, Sb, Zn) and OCs (Polychlorinated biphenyls, PCBs; Hexachlorocyclohexanes, HCHs; Dichlorodiphenyltrichloroethane and its metabolites, DDTs). Data were compared to levels in liver and muscle tissues. Eel brain contained very high amounts of OCs, superior to those found in the two other tissues. Interestingly, the relative abundance of PCB congeners markedly differed between tissues. In brain, a predominance of low chlorinated PCBs was noted, whereas highly chlorinated congeners prevailed in muscle and liver. HCHs were particularly abundant in brain, which contains the highest amounts of β-HCH and Υ-HCH. p,p'-DDTs concentration was similar between brain and muscle (i.e., about twice that of liver). A higher proportion of p,p'-DDT was noticed in brain. Except for Cr and inorganic Hg, all potentially neurotoxic metals accumulated in brain to levels equal to or lower than hepatic levels. Altogether, results indicate that eel brain is an important target for organic and, to a lesser extent, for inorganic neurotoxic pollutants. Article in Journal/Newspaper Anguilla anguilla Research Portal - University of Namur Environmental Toxicology and Pharmacology 45 346 355 |
institution |
Open Polar |
collection |
Research Portal - University of Namur |
op_collection_id |
ftunivnamurcrisp |
language |
English |
topic |
Brain Eel Mercury Metals Organochlorine pesticides PCBs Toxicology /dk/atira/pure/subjectarea/asjc/3000/3005 /dk/atira/pure/subjectarea/asjc/2300/2307 Health Toxicology and Mutagenesis /dk/atira/pure/subjectarea/asjc/3000/3004 Pharmacology |
spellingShingle |
Brain Eel Mercury Metals Organochlorine pesticides PCBs Toxicology /dk/atira/pure/subjectarea/asjc/3000/3005 /dk/atira/pure/subjectarea/asjc/2300/2307 Health Toxicology and Mutagenesis /dk/atira/pure/subjectarea/asjc/3000/3004 Pharmacology Bonnineau, C. Scaion, D. Lemaire, B. Belpaire, Claude THOMÉ, Jean-Pierre Thonon, M. Leermaker, M. Gao, Y. Debier, C. Silvestre, F. Kestemont, P. Rees, Jean-François Accumulation of neurotoxic organochlorines and trace elements in brain of female European eel (Anguilla anguilla) |
topic_facet |
Brain Eel Mercury Metals Organochlorine pesticides PCBs Toxicology /dk/atira/pure/subjectarea/asjc/3000/3005 /dk/atira/pure/subjectarea/asjc/2300/2307 Health Toxicology and Mutagenesis /dk/atira/pure/subjectarea/asjc/3000/3004 Pharmacology |
description |
Xenobiotics such as organochlorine compounds (OCs) and metals have been suggested to play a significant role in the collapse of European eel stocks in the last decades. Several of these pollutants could affect functioning of the nervous system. Still, no information is so far available on levels of potentially neurotoxic pollutants in eel brain. In present study, carried out on female eels caught in Belgian rivers and canals, we analyzed brain levels of potentially-neurotoxic trace elements (Ag, Al, As, Cd, Co, Cr, Cu, Fe, Hg, MeHg, Mn, Ni, Pb, Sn, Sb, Zn) and OCs (Polychlorinated biphenyls, PCBs; Hexachlorocyclohexanes, HCHs; Dichlorodiphenyltrichloroethane and its metabolites, DDTs). Data were compared to levels in liver and muscle tissues. Eel brain contained very high amounts of OCs, superior to those found in the two other tissues. Interestingly, the relative abundance of PCB congeners markedly differed between tissues. In brain, a predominance of low chlorinated PCBs was noted, whereas highly chlorinated congeners prevailed in muscle and liver. HCHs were particularly abundant in brain, which contains the highest amounts of β-HCH and Υ-HCH. p,p'-DDTs concentration was similar between brain and muscle (i.e., about twice that of liver). A higher proportion of p,p'-DDT was noticed in brain. Except for Cr and inorganic Hg, all potentially neurotoxic metals accumulated in brain to levels equal to or lower than hepatic levels. Altogether, results indicate that eel brain is an important target for organic and, to a lesser extent, for inorganic neurotoxic pollutants. |
format |
Article in Journal/Newspaper |
author |
Bonnineau, C. Scaion, D. Lemaire, B. Belpaire, Claude THOMÉ, Jean-Pierre Thonon, M. Leermaker, M. Gao, Y. Debier, C. Silvestre, F. Kestemont, P. Rees, Jean-François |
author_facet |
Bonnineau, C. Scaion, D. Lemaire, B. Belpaire, Claude THOMÉ, Jean-Pierre Thonon, M. Leermaker, M. Gao, Y. Debier, C. Silvestre, F. Kestemont, P. Rees, Jean-François |
author_sort |
Bonnineau, C. |
title |
Accumulation of neurotoxic organochlorines and trace elements in brain of female European eel (Anguilla anguilla) |
title_short |
Accumulation of neurotoxic organochlorines and trace elements in brain of female European eel (Anguilla anguilla) |
title_full |
Accumulation of neurotoxic organochlorines and trace elements in brain of female European eel (Anguilla anguilla) |
title_fullStr |
Accumulation of neurotoxic organochlorines and trace elements in brain of female European eel (Anguilla anguilla) |
title_full_unstemmed |
Accumulation of neurotoxic organochlorines and trace elements in brain of female European eel (Anguilla anguilla) |
title_sort |
accumulation of neurotoxic organochlorines and trace elements in brain of female european eel (anguilla anguilla) |
publishDate |
2016 |
url |
https://researchportal.unamur.be/en/publications/accumulation-of-neurotoxic-organochlorines-and-trace-elements-in-brain-of-female-european-eel-anguilla-anguilla(d76975ef-73f8-493c-acd3-bf3553010b2f).html https://doi.org/10.1016/j.etap.2016.06.009 http://www.scopus.com/inward/record.url?scp=84976353356&partnerID=8YFLogxK |
genre |
Anguilla anguilla |
genre_facet |
Anguilla anguilla |
op_source |
Bonnineau , C , Scaion , D , Lemaire , B , Belpaire , C , THOMÉ , J-P , Thonon , M , Leermaker , M , Gao , Y , Debier , C , Silvestre , F , Kestemont , P & Rees , J-F 2016 , ' Accumulation of neurotoxic organochlorines and trace elements in brain of female European eel (Anguilla anguilla) ' , Environmental Toxicology and Pharmacology , vol. 45 , pp. 346-355 . https://doi.org/10.1016/j.etap.2016.06.009 |
op_rights |
info:eu-repo/semantics/closedAccess |
op_doi |
https://doi.org/10.1016/j.etap.2016.06.009 |
container_title |
Environmental Toxicology and Pharmacology |
container_volume |
45 |
container_start_page |
346 |
op_container_end_page |
355 |
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1766401885503225856 |