Dioxin-like activities in serum across European and Inuit populations.

Persistent organic pollutants (POPs) such as polychlorinated dibenzo-p-dioxins/furans, polychlorinated biphenyls (PCBs) and organochlorine pesticides can cause a series of adverse effects on e.g. reproduction in animals and humans, many of which involve the aryl hydrocarbon receptor (AhR). The aim o...

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Bibliographic Details
Published in:Environmental Health
Main Authors: LONG M, ANDERSEN BS, LINDH CH, HAGMAR L, GIWERCMAN A, MANICARDI, Gian Carlo, BIZZARO D, SPAN M, TOFT G, PEDERSEN HS, ZVYEZDAY V, BONDE JP, BONEFELD JORGENSEN EC
Other Authors: Long, M, Andersen, B, Lindh, Ch, Hagmar, L, Giwercman, A, Manicardi, Gian Carlo, Bizzaro, D, Span, M, Toft, G, Pedersen, H, Zvyezday, V, Bonde, Jp, BONEFELD JORGENSEN, Ec
Format: Article in Journal/Newspaper
Language:English
Published: London : BioMed Central, [2002- 2006
Subjects:
POP
reproduction
aryl hydrocarbon receptor (AhR)
Inuit population
(CB-153)
(p
p'-DDE)
inuit
Online Access:http://hdl.handle.net/11380/455190
https://doi.org/10.1186/1476-069X-5-14
Description
Summary:Persistent organic pollutants (POPs) such as polychlorinated dibenzo-p-dioxins/furans, polychlorinated biphenyls (PCBs) and organochlorine pesticides can cause a series of adverse effects on e.g. reproduction in animals and humans, many of which involve the aryl hydrocarbon receptor (AhR). The aim of the present study was to compare the integrated serum level of AhR mediated activity among European and Inuit populations, and evaluate whether the activity was associated to the selected POP markers, 2,2',4,4',5,5'-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis(p-chlorophenyl)-ethylene (p,p'-DDE).

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