Choline is an essential nutrient for post-smolt Atlantic salmon (Salmo salar L)
The aquaculture feed industry continuously works to decrease the share of marine ingredients in the diets by searching for alternative feed ingredients. The increased use of such ingredients, on one hand expose the fish for new components, and on the other hand reduce the levels of components typica...
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Norwegian University of Life Sciences, Ås
2020
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Online Access: | https://hdl.handle.net/11250/3017060 |
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ftunivmob:oai:nmbu.brage.unit.no:11250/3017060 2023-05-15T15:30:26+02:00 Choline is an essential nutrient for post-smolt Atlantic salmon (Salmo salar L) Kolin er et essensielt næringsstoff for post-smolt Atlantisk laks (Salmo salar L) Hansen, Anne Kristine Grostøl Krogdahl, Åshild Hillestad, Marie Denstadli, Vegard Kortner, Trond 2020 application/pdf https://hdl.handle.net/11250/3017060 eng eng Norwegian University of Life Sciences, Ås PhD Thesis;2020:27 urn:isbn:978-82-575-1690-1 urn:issn:1894-6402 https://hdl.handle.net/11250/3017060 Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal http://creativecommons.org/licenses/by-nc-nd/4.0/deed.no CC-BY-NC-ND Choline Atlantic salmon Lipid malabsorption Lipid transport Requirement Kolin Doctoral thesis 2020 ftunivmob 2022-09-14T22:42:26Z The aquaculture feed industry continuously works to decrease the share of marine ingredients in the diets by searching for alternative feed ingredients. The increased use of such ingredients, on one hand expose the fish for new components, and on the other hand reduce the levels of components typical for diets rich in marine ingredients. Salmon diets have, over the last decades, also changed regarding lipid content. The level has increased, whereas the proportion of n-3 fatty acids has decreased. These changes may present challenges for the aquaculture industry. Fish farmers have, since 2000, reported symptoms of lipid malabsorption (LMS) in young as well as more mature salmon. The typically characteristics of LMS are swollen, pale and coarse appearance of the pyloric and mid intestine as a result of lipid accumulation in the tissue, seen histologically as large vacuoles. Previous studies have indicated that impaired lipoprotein formation, as a result of lack of phosphatidylcholine, could be the cause of the formation of excessive intestinal lipid vacuolation. Phosphatidylcholine is not considered as an essential nutrient for any fish species as it can be synthesized if sufficient choline is present. However, essentiality of choline has been established for many animal species, including some fish species in particularly for early stages, but not for any life stages of Atlantic salmon. In this thesis, three separate experiments were conducted to increase knowledge on the effects of choline and other key components involved in lipid and sterol metabolism on the development of LMS in Atlantic salmon in seawater. The experiments included firstly investigating whether choline chloride could prevent LMS. Secondly, whether other key components in lipid and sterol metabolism may modify the development of symptoms of LMS. The goal of the last experiment was to define the dietary requirement of choline for Atlantic salmon in seawater. The results from the first experiment showed that fish fed a diet with a choline level ... Doctoral or Postdoctoral Thesis Atlantic salmon Salmo salar Open archive Norwegian University of Life Sciences: Brage NMBU |
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Open Polar |
collection |
Open archive Norwegian University of Life Sciences: Brage NMBU |
op_collection_id |
ftunivmob |
language |
English |
topic |
Choline Atlantic salmon Lipid malabsorption Lipid transport Requirement Kolin |
spellingShingle |
Choline Atlantic salmon Lipid malabsorption Lipid transport Requirement Kolin Hansen, Anne Kristine Grostøl Choline is an essential nutrient for post-smolt Atlantic salmon (Salmo salar L) |
topic_facet |
Choline Atlantic salmon Lipid malabsorption Lipid transport Requirement Kolin |
description |
The aquaculture feed industry continuously works to decrease the share of marine ingredients in the diets by searching for alternative feed ingredients. The increased use of such ingredients, on one hand expose the fish for new components, and on the other hand reduce the levels of components typical for diets rich in marine ingredients. Salmon diets have, over the last decades, also changed regarding lipid content. The level has increased, whereas the proportion of n-3 fatty acids has decreased. These changes may present challenges for the aquaculture industry. Fish farmers have, since 2000, reported symptoms of lipid malabsorption (LMS) in young as well as more mature salmon. The typically characteristics of LMS are swollen, pale and coarse appearance of the pyloric and mid intestine as a result of lipid accumulation in the tissue, seen histologically as large vacuoles. Previous studies have indicated that impaired lipoprotein formation, as a result of lack of phosphatidylcholine, could be the cause of the formation of excessive intestinal lipid vacuolation. Phosphatidylcholine is not considered as an essential nutrient for any fish species as it can be synthesized if sufficient choline is present. However, essentiality of choline has been established for many animal species, including some fish species in particularly for early stages, but not for any life stages of Atlantic salmon. In this thesis, three separate experiments were conducted to increase knowledge on the effects of choline and other key components involved in lipid and sterol metabolism on the development of LMS in Atlantic salmon in seawater. The experiments included firstly investigating whether choline chloride could prevent LMS. Secondly, whether other key components in lipid and sterol metabolism may modify the development of symptoms of LMS. The goal of the last experiment was to define the dietary requirement of choline for Atlantic salmon in seawater. The results from the first experiment showed that fish fed a diet with a choline level ... |
author2 |
Krogdahl, Åshild Hillestad, Marie Denstadli, Vegard Kortner, Trond |
format |
Doctoral or Postdoctoral Thesis |
author |
Hansen, Anne Kristine Grostøl |
author_facet |
Hansen, Anne Kristine Grostøl |
author_sort |
Hansen, Anne Kristine Grostøl |
title |
Choline is an essential nutrient for post-smolt Atlantic salmon (Salmo salar L) |
title_short |
Choline is an essential nutrient for post-smolt Atlantic salmon (Salmo salar L) |
title_full |
Choline is an essential nutrient for post-smolt Atlantic salmon (Salmo salar L) |
title_fullStr |
Choline is an essential nutrient for post-smolt Atlantic salmon (Salmo salar L) |
title_full_unstemmed |
Choline is an essential nutrient for post-smolt Atlantic salmon (Salmo salar L) |
title_sort |
choline is an essential nutrient for post-smolt atlantic salmon (salmo salar l) |
publisher |
Norwegian University of Life Sciences, Ås |
publishDate |
2020 |
url |
https://hdl.handle.net/11250/3017060 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_relation |
PhD Thesis;2020:27 urn:isbn:978-82-575-1690-1 urn:issn:1894-6402 https://hdl.handle.net/11250/3017060 |
op_rights |
Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal http://creativecommons.org/licenses/by-nc-nd/4.0/deed.no |
op_rightsnorm |
CC-BY-NC-ND |
_version_ |
1766360876425674752 |