Genetically modified attenuated salmonid alphavirus: A potential strategy for immunization of Atlantic salmon

• Published in: Journal of Fish Diseases
• Main Authors: Aksnes, Ida, Braaen, Stine, Markussen, Turhan Ali Dadasbilge, Åkesson, Caroline Piercey, Villoing, Stephane, Rimstad, Espen
• Format: Article in Journal/Newspaper
• Language: English
• Published: 2021
• Subjects: Sav’; Atlantic salmon
• Online Access: https://hdl.handle.net/11250/2787008; https://doi.org/10.1111/jfd.13352

Pancreas disease (PD) is a serious challenge in European salmonid aquaculture caused by salmonid alphavirus (SAV). In this study, we report the effect of immunization of Atlantic salmon with three attenuated infectious SAV3 strains with targeted mutations in a glycosylation site of the envelope E2 p...