Variation in the Innate and Acquired Arms of the Immune System Among Five Shorebird Species
To contribute to an understanding of the evolutionary processes that shape variation in immune responses, we compared several components of the innate and acquired arms of the immune system in five related, but ecologically diverse, migratory shorebirds (ruff Philomachus pugnax L., ruddy turnstone A...
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ftunivmissouriir:oai:irl.umsl.edu:biology-faculty-1031 2024-04-21T07:56:24+00:00 Variation in the Innate and Acquired Arms of the Immune System Among Five Shorebird Species Mendes, Luisa Piersma, Theunis Hasselquist, Dennis Matson, Kevin Ricklefs, Robert 2006-01-15T08:00:00Z application/pdf https://irl.umsl.edu/biology-faculty/32 https://doi.org/10.1242/jeb.02015 https://irl.umsl.edu/context/biology-faculty/article/1031/viewcontent/.pdf unknown IRL @ UMSL https://irl.umsl.edu/biology-faculty/32 doi:10.1242/jeb.02015 https://irl.umsl.edu/context/biology-faculty/article/1031/viewcontent/.pdf Biology Department Faculty Works Biology Immunology and Infectious Disease text 2006 ftunivmissouriir https://doi.org/10.1242/jeb.02015 2024-03-25T15:39:57Z To contribute to an understanding of the evolutionary processes that shape variation in immune responses, we compared several components of the innate and acquired arms of the immune system in five related, but ecologically diverse, migratory shorebirds (ruff Philomachus pugnax L., ruddy turnstone Arenaria interpres L., bar-tailed godwit Limosa lapponica L., sanderling Calidris alba Pallas and red knotC. canutus L.). We used a hemolysis-hemagglutination assay in free-living shorebirds to assess two of the innate components (natural antibodies and complement-mediated lysis), and a modified quantitative enzyme-linked immunosorbent assay in birds held in captivity to assess the acquired component (humoral antibodies against tetanus and diphtheria toxoid) of immunity. Ruddy turnstones showed the highest levels of both innate and acquired immune responses. We suggest that turnstones could have evolved strong immune responses because they scavenge among rotting organic material on the seashore, where they might be exposed to a particularly broad range of pathogens. Although ruffs stand out among shorebirds in having a high prevalence of avian malaria, they do not exhibit higher immune response levels. Our results indicate that relationships between immune response and infection are not likely to follow a broad general pattern, but instead depend on type of parasite exposure, among other factors. Text Arenaria interpres Calidris alba Philomachus pugnax Ruddy Turnstone Ruff Sanderling University of Missouri, St. Louis: IRL @ UMSL Journal of Experimental Biology 209 2 284 291 |
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University of Missouri, St. Louis: IRL @ UMSL |
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ftunivmissouriir |
language |
unknown |
topic |
Biology Immunology and Infectious Disease |
spellingShingle |
Biology Immunology and Infectious Disease Mendes, Luisa Piersma, Theunis Hasselquist, Dennis Matson, Kevin Ricklefs, Robert Variation in the Innate and Acquired Arms of the Immune System Among Five Shorebird Species |
topic_facet |
Biology Immunology and Infectious Disease |
description |
To contribute to an understanding of the evolutionary processes that shape variation in immune responses, we compared several components of the innate and acquired arms of the immune system in five related, but ecologically diverse, migratory shorebirds (ruff Philomachus pugnax L., ruddy turnstone Arenaria interpres L., bar-tailed godwit Limosa lapponica L., sanderling Calidris alba Pallas and red knotC. canutus L.). We used a hemolysis-hemagglutination assay in free-living shorebirds to assess two of the innate components (natural antibodies and complement-mediated lysis), and a modified quantitative enzyme-linked immunosorbent assay in birds held in captivity to assess the acquired component (humoral antibodies against tetanus and diphtheria toxoid) of immunity. Ruddy turnstones showed the highest levels of both innate and acquired immune responses. We suggest that turnstones could have evolved strong immune responses because they scavenge among rotting organic material on the seashore, where they might be exposed to a particularly broad range of pathogens. Although ruffs stand out among shorebirds in having a high prevalence of avian malaria, they do not exhibit higher immune response levels. Our results indicate that relationships between immune response and infection are not likely to follow a broad general pattern, but instead depend on type of parasite exposure, among other factors. |
format |
Text |
author |
Mendes, Luisa Piersma, Theunis Hasselquist, Dennis Matson, Kevin Ricklefs, Robert |
author_facet |
Mendes, Luisa Piersma, Theunis Hasselquist, Dennis Matson, Kevin Ricklefs, Robert |
author_sort |
Mendes, Luisa |
title |
Variation in the Innate and Acquired Arms of the Immune System Among Five Shorebird Species |
title_short |
Variation in the Innate and Acquired Arms of the Immune System Among Five Shorebird Species |
title_full |
Variation in the Innate and Acquired Arms of the Immune System Among Five Shorebird Species |
title_fullStr |
Variation in the Innate and Acquired Arms of the Immune System Among Five Shorebird Species |
title_full_unstemmed |
Variation in the Innate and Acquired Arms of the Immune System Among Five Shorebird Species |
title_sort |
variation in the innate and acquired arms of the immune system among five shorebird species |
publisher |
IRL @ UMSL |
publishDate |
2006 |
url |
https://irl.umsl.edu/biology-faculty/32 https://doi.org/10.1242/jeb.02015 https://irl.umsl.edu/context/biology-faculty/article/1031/viewcontent/.pdf |
genre |
Arenaria interpres Calidris alba Philomachus pugnax Ruddy Turnstone Ruff Sanderling |
genre_facet |
Arenaria interpres Calidris alba Philomachus pugnax Ruddy Turnstone Ruff Sanderling |
op_source |
Biology Department Faculty Works |
op_relation |
https://irl.umsl.edu/biology-faculty/32 doi:10.1242/jeb.02015 https://irl.umsl.edu/context/biology-faculty/article/1031/viewcontent/.pdf |
op_doi |
https://doi.org/10.1242/jeb.02015 |
container_title |
Journal of Experimental Biology |
container_volume |
209 |
container_issue |
2 |
container_start_page |
284 |
op_container_end_page |
291 |
_version_ |
1796938431451889664 |