Comparing toxicity and bioactivity of gold nanoparticles synthetized using two brown algae Cystoseira sp

• Published in: Frontiers in Marine Science
• Main Authors: Machado, Sofia, Gonçalves, Anabela Ferreira, González-Ballesteros, Noelia, Magalhães, Luana, Passos, Marisa Sárria Pereira, Rodríguez-Argüelles, Maria Carmen, Gomes, Andreia C
• Format: Other/Unknown Material
• Language: English
• Published: Frontiers Media 2019
• Subjects: Green synthesis and nanoparticles; Algae extracts; Zebrafish embryo acute toxicity test; Cell regeneration; Gold nanoparticles; North East Atlantic
• Online Access: http://hdl.handle.net/1822/61849; https://doi.org/10.3389/conf.fmars.2019.08.00155

The marine ecosystem has captured a major attention in recent years since various biologically active compounds have been isolated and screened for pharmacological activity from dissimilar marine provenience. Marine biological resources can be considered an essential for nanotechnology, researchers had been interested to synthesize metallic nanoparticles from marine source because it is thought to be ecofriendly, nontoxic, environmentally acceptable ‘‘green procedures”, reduces the down-streaming process making it very cost effective and the availableness of the source from the diverse marine ecosystem becomes a much easier task. The biosynthesized nanoparticles from marine compound offer stabilized nanoparticles through compounds present in the marine source that make them more efficient for both biomedical and industrial applications[1]. In this regard, we have focus our attention in two algae of Cystoseira. It is a genus of marine brown macroalgae composed of about 40 species. It is widely distributed in the North East Atlantic, the Baltic Sea and the Mediterranean. This genus contains a wide variety of secondary metabolites (e.g. terpenoids, steroids, phlorotannins, phenolic compounds, carbohydrates, triacylglycerols/fatty acids, pigments, vitamins) that are associated with pharmacological properties, such as antioxidant, anti-inflammatory, cytotoxicity, anticancer, cholinesterase inhibition and anti-diabetic activities but also antibacterial, antifungal and anti-parasitic activities [2]. Cystoseira baccata (CB) and Cystoseira tamariscifolia (CT) are two species of this genus that differ in geographic distribution, morphology and possibly content of secondary metabolites. Gold nanoparticles are presently under intensive study since they can be the remarkable scaffold for novel biological and chemical applications owing to their unique electrical, chemical and optical properties. Such as their easy synthesis and good biocompatibility due to the low reactivity of the golden core. Therefore presenting potential ...