Inside the Alterations of Circulating Metabolome in Antarctica: The Adaptation to Chronic Hypoxia

• Published in: Frontiers in Physiology
• Main Authors: M. Dei Cas, C. Morano, S. Ottolenghi, R. Dicasillati, G. Roda, M. Samaja, R. Paroni
• Other Authors: M. Dei Ca
• Format: Article in Journal/Newspaper
• Language: English
• Published: Frontiers Research Foundation 2022
• Subjects: adaptation; Antarctica; chronic hypoxia; lipidomic; metabolite; metabolomic; Settore BIO/10 - Biochimica; Settore BIO/12 - Biochimica Clinica e Biologia Molecolare Clinica; Concordia Station; Antarc*
• Online Access: http://hdl.handle.net/2434/899725; https://doi.org/10.3389/fphys.2022.819345

Although the human body may dynamically adapt to mild and brief oxygen shortages, there is a growing interest in understanding how the metabolic pathways are modified during sustained exposure to chronic hypoxia. Located at an equivalent altitude of approximately 3,800 m asl, the Concordia Station i...