Surveillance of anti-tuberculosis drug resistance in the world: an updated analysis, 2007-2010
Objective To present a global update of drug-resistant tuberculosis (TB) and explore trends in 1994-2010. Methods Data on drug resistance among new and previously treated TB patients, as reported by countries to the World Health Organization, were analysed. Such data are collected through surveys of...
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ftunivmilanoair:oai:air.unimi.it:2434/626545 2024-02-11T10:05:52+01:00 Surveillance of anti-tuberculosis drug resistance in the world: an updated analysis, 2007-2010 Matteo Zignol Wayne van Gemert Dennis Falzon Charalambos Sismanidis Philippe Glaziou Katherine Floyd Mario Raviglione M. Zignol W. van Gemert D. Falzon C. Sismanidi P. Glaziou K. Floyd M. Raviglione 2011 http://hdl.handle.net/2434/626545 https://doi.org/10.2471/blt.11.092585 eng eng info:eu-repo/semantics/altIdentifier/pmid/22423162 info:eu-repo/semantics/altIdentifier/wos/WOS:000299982200019 volume:90 issue:2 firstpage:111 lastpage:119 numberofpages:9 journal:BULLETIN OF THE WORLD HEALTH ORGANIZATION http://hdl.handle.net/2434/626545 doi:10.2471/blt.11.092585 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84856607254 info:eu-repo/semantics/openAccess Global surveillance tuberculosi project outbreak Settore MED/17 - Malattie Infettive info:eu-repo/semantics/article 2011 ftunivmilanoair https://doi.org/10.2471/blt.11.092585 2024-01-23T23:35:41Z Objective To present a global update of drug-resistant tuberculosis (TB) and explore trends in 1994-2010. Methods Data on drug resistance among new and previously treated TB patients, as reported by countries to the World Health Organization, were analysed. Such data are collected through surveys of a representative sample of TB patients or surveillance systems based on routine drug susceptibility testing. Associations between multidrug-resistant TB (MDR-TB) and human immunodeficiency virus (HIV) infection and sex were explored through logistic regression. Findings In 2007-2010, 80 countries and 8 territories reported surveillance data. MDR-TB among new and previously treated cases was highest in the Russian Federation (Murmansk oblast, 28.9%) and the Republic of Moldova (65.1%), respectively. In three former Soviet Union countries and South Africa, more than 10% of the cases of MDR-TB were extensively drug-resistant. Globally, in 1994 to 2010 multidrug resistance was observed in 3.4% (95% confidence interval, Cl: 1.9-5.0) of all new TB case's and in 19.8% (95% Cl: 14.4-25.1) of previously treated TB cases. No overall associations between MDR-TB and HIV infection (odds ratio, OR: 1.4; 95% Cl: 0.7-3.0) or sex (OR: 1.1; 95% Cl: 0.8-1.4) were found. Between 1994 and 2010, MDR-TB rates in the general population increased in Botswana, Peru, the Republic of Korea and declined in Estonia, Latvia and the United States of America. Conclusion The highest global rates of MDR-TB ever reported were documented in 2009 and 2010. Trends in MDR-TB are still unclear in most settings. Better surveillance or survey data are required, especially from Africa and India. Article in Journal/Newspaper Murmansk Oblast The University of Milan: Archivio Istituzionale della Ricerca (AIR) Murmansk Bulletin of the World Health Organization 90 2 111 119D |
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The University of Milan: Archivio Istituzionale della Ricerca (AIR) |
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ftunivmilanoair |
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English |
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Global surveillance tuberculosi project outbreak Settore MED/17 - Malattie Infettive |
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Global surveillance tuberculosi project outbreak Settore MED/17 - Malattie Infettive Matteo Zignol Wayne van Gemert Dennis Falzon Charalambos Sismanidis Philippe Glaziou Katherine Floyd Mario Raviglione Surveillance of anti-tuberculosis drug resistance in the world: an updated analysis, 2007-2010 |
topic_facet |
Global surveillance tuberculosi project outbreak Settore MED/17 - Malattie Infettive |
description |
Objective To present a global update of drug-resistant tuberculosis (TB) and explore trends in 1994-2010. Methods Data on drug resistance among new and previously treated TB patients, as reported by countries to the World Health Organization, were analysed. Such data are collected through surveys of a representative sample of TB patients or surveillance systems based on routine drug susceptibility testing. Associations between multidrug-resistant TB (MDR-TB) and human immunodeficiency virus (HIV) infection and sex were explored through logistic regression. Findings In 2007-2010, 80 countries and 8 territories reported surveillance data. MDR-TB among new and previously treated cases was highest in the Russian Federation (Murmansk oblast, 28.9%) and the Republic of Moldova (65.1%), respectively. In three former Soviet Union countries and South Africa, more than 10% of the cases of MDR-TB were extensively drug-resistant. Globally, in 1994 to 2010 multidrug resistance was observed in 3.4% (95% confidence interval, Cl: 1.9-5.0) of all new TB case's and in 19.8% (95% Cl: 14.4-25.1) of previously treated TB cases. No overall associations between MDR-TB and HIV infection (odds ratio, OR: 1.4; 95% Cl: 0.7-3.0) or sex (OR: 1.1; 95% Cl: 0.8-1.4) were found. Between 1994 and 2010, MDR-TB rates in the general population increased in Botswana, Peru, the Republic of Korea and declined in Estonia, Latvia and the United States of America. Conclusion The highest global rates of MDR-TB ever reported were documented in 2009 and 2010. Trends in MDR-TB are still unclear in most settings. Better surveillance or survey data are required, especially from Africa and India. |
author2 |
M. Zignol W. van Gemert D. Falzon C. Sismanidi P. Glaziou K. Floyd M. Raviglione |
format |
Article in Journal/Newspaper |
author |
Matteo Zignol Wayne van Gemert Dennis Falzon Charalambos Sismanidis Philippe Glaziou Katherine Floyd Mario Raviglione |
author_facet |
Matteo Zignol Wayne van Gemert Dennis Falzon Charalambos Sismanidis Philippe Glaziou Katherine Floyd Mario Raviglione |
author_sort |
Matteo Zignol |
title |
Surveillance of anti-tuberculosis drug resistance in the world: an updated analysis, 2007-2010 |
title_short |
Surveillance of anti-tuberculosis drug resistance in the world: an updated analysis, 2007-2010 |
title_full |
Surveillance of anti-tuberculosis drug resistance in the world: an updated analysis, 2007-2010 |
title_fullStr |
Surveillance of anti-tuberculosis drug resistance in the world: an updated analysis, 2007-2010 |
title_full_unstemmed |
Surveillance of anti-tuberculosis drug resistance in the world: an updated analysis, 2007-2010 |
title_sort |
surveillance of anti-tuberculosis drug resistance in the world: an updated analysis, 2007-2010 |
publishDate |
2011 |
url |
http://hdl.handle.net/2434/626545 https://doi.org/10.2471/blt.11.092585 |
geographic |
Murmansk |
geographic_facet |
Murmansk |
genre |
Murmansk Oblast |
genre_facet |
Murmansk Oblast |
op_relation |
info:eu-repo/semantics/altIdentifier/pmid/22423162 info:eu-repo/semantics/altIdentifier/wos/WOS:000299982200019 volume:90 issue:2 firstpage:111 lastpage:119 numberofpages:9 journal:BULLETIN OF THE WORLD HEALTH ORGANIZATION http://hdl.handle.net/2434/626545 doi:10.2471/blt.11.092585 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84856607254 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.2471/blt.11.092585 |
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Bulletin of the World Health Organization |
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90 |
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2 |
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111 |
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119D |
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1790603082833330176 |