The Prevalence of Chronic Obstructive Pulmonary Disease by the Global Lung Initiative Equations in North-Western Russia.
BACKGROUND: The prevalence of chronic obstructive pulmonary disease (COPD) varies in different countries, while the cut-off for airflow obstruction (AO) is still contested. No COPD prevalence data based on the Global Lung Initiative (GLI) 2012 equations are available in Russia. OBJECTIVES: This stud...
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Online Access: | http://hdl.handle.net/2078.1/169598 https://doi.org/10.1159/000442887 |
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ftunivlouvain:oai:dial.uclouvain.be:boreal:169598 2024-05-19T07:45:44+00:00 The Prevalence of Chronic Obstructive Pulmonary Disease by the Global Lung Initiative Equations in North-Western Russia. Andreeva, Elena Pokhaznikova, Marina Lebedev, Anatoly Moiseeva, Irina Kutznetsova, Olga Degryse, Jean-Marie UCL - SSS/IRSS - Institut de recherche santé et société 2016 http://hdl.handle.net/2078.1/169598 https://doi.org/10.1159/000442887 eng eng S.Karger AG boreal:169598 http://hdl.handle.net/2078.1/169598 doi:10.1159/000442887 info:pmid/26727503 urn:ISSN:0025-7931 urn:EISSN:1423-0356 info:eu-repo/semantics/closedAccess Respiration (English Edition) : international journal of thoracic medicine, Vol. 91, no.1, p. 20-28 (2016) info:eu-repo/semantics/article 2016 ftunivlouvain https://doi.org/10.1159/000442887 2024-04-24T01:26:16Z BACKGROUND: The prevalence of chronic obstructive pulmonary disease (COPD) varies in different countries, while the cut-off for airflow obstruction (AO) is still contested. No COPD prevalence data based on the Global Lung Initiative (GLI) 2012 equations are available in Russia. OBJECTIVES: This study aims to assess AO prevalence by the GLI lower limit of normal (GLI-LLN) and the fixed cut-off, to identify AO risk factors and to assess the diagnostic value of respiratory symptoms in north-western Russia. METHODS: In a north-western Russian population-based sample of 2,974 adults aged 35-70 years, data on socio-demographics, smoking, occupational exposures and respiratory symptoms were collected, and spirometry was performed before and after bronchodilator (BD) administration. RESULTS: The AO prevalence was 6.8% (95% CI 5.8-7.9) based on the fixed and 4.8% (95% CI 3.9-5.7) based on the GLI-LLN cut-off. 22.5% of the participants with post-BD AO had a positive bronchodilator test, and 1% showed a paradoxical BD response. Of the environmental factors studied, only smoking was independently associated with AO (odds ratio 2.47, 95% CI 1.60-3.82). The positive predictive value of respiratory symptoms for AO was 11% based on the fixed and 8% based on the GLI-LLN cut-off. CONCLUSIONS: In a sample of adults in north-western Russia, the AO prevalence by the GLI-LLN cut-off was lower than that by the fixed cut-off. The predictive value of respiratory symptoms was low. Article in Journal/Newspaper North-Western Russia DIAL@UCLouvain (Université catholique de Louvain) Respiration 91 1 43 55 |
institution |
Open Polar |
collection |
DIAL@UCLouvain (Université catholique de Louvain) |
op_collection_id |
ftunivlouvain |
language |
English |
description |
BACKGROUND: The prevalence of chronic obstructive pulmonary disease (COPD) varies in different countries, while the cut-off for airflow obstruction (AO) is still contested. No COPD prevalence data based on the Global Lung Initiative (GLI) 2012 equations are available in Russia. OBJECTIVES: This study aims to assess AO prevalence by the GLI lower limit of normal (GLI-LLN) and the fixed cut-off, to identify AO risk factors and to assess the diagnostic value of respiratory symptoms in north-western Russia. METHODS: In a north-western Russian population-based sample of 2,974 adults aged 35-70 years, data on socio-demographics, smoking, occupational exposures and respiratory symptoms were collected, and spirometry was performed before and after bronchodilator (BD) administration. RESULTS: The AO prevalence was 6.8% (95% CI 5.8-7.9) based on the fixed and 4.8% (95% CI 3.9-5.7) based on the GLI-LLN cut-off. 22.5% of the participants with post-BD AO had a positive bronchodilator test, and 1% showed a paradoxical BD response. Of the environmental factors studied, only smoking was independently associated with AO (odds ratio 2.47, 95% CI 1.60-3.82). The positive predictive value of respiratory symptoms for AO was 11% based on the fixed and 8% based on the GLI-LLN cut-off. CONCLUSIONS: In a sample of adults in north-western Russia, the AO prevalence by the GLI-LLN cut-off was lower than that by the fixed cut-off. The predictive value of respiratory symptoms was low. |
author2 |
UCL - SSS/IRSS - Institut de recherche santé et société |
format |
Article in Journal/Newspaper |
author |
Andreeva, Elena Pokhaznikova, Marina Lebedev, Anatoly Moiseeva, Irina Kutznetsova, Olga Degryse, Jean-Marie |
spellingShingle |
Andreeva, Elena Pokhaznikova, Marina Lebedev, Anatoly Moiseeva, Irina Kutznetsova, Olga Degryse, Jean-Marie The Prevalence of Chronic Obstructive Pulmonary Disease by the Global Lung Initiative Equations in North-Western Russia. |
author_facet |
Andreeva, Elena Pokhaznikova, Marina Lebedev, Anatoly Moiseeva, Irina Kutznetsova, Olga Degryse, Jean-Marie |
author_sort |
Andreeva, Elena |
title |
The Prevalence of Chronic Obstructive Pulmonary Disease by the Global Lung Initiative Equations in North-Western Russia. |
title_short |
The Prevalence of Chronic Obstructive Pulmonary Disease by the Global Lung Initiative Equations in North-Western Russia. |
title_full |
The Prevalence of Chronic Obstructive Pulmonary Disease by the Global Lung Initiative Equations in North-Western Russia. |
title_fullStr |
The Prevalence of Chronic Obstructive Pulmonary Disease by the Global Lung Initiative Equations in North-Western Russia. |
title_full_unstemmed |
The Prevalence of Chronic Obstructive Pulmonary Disease by the Global Lung Initiative Equations in North-Western Russia. |
title_sort |
prevalence of chronic obstructive pulmonary disease by the global lung initiative equations in north-western russia. |
publisher |
S.Karger AG |
publishDate |
2016 |
url |
http://hdl.handle.net/2078.1/169598 https://doi.org/10.1159/000442887 |
genre |
North-Western Russia |
genre_facet |
North-Western Russia |
op_source |
Respiration (English Edition) : international journal of thoracic medicine, Vol. 91, no.1, p. 20-28 (2016) |
op_relation |
boreal:169598 http://hdl.handle.net/2078.1/169598 doi:10.1159/000442887 info:pmid/26727503 urn:ISSN:0025-7931 urn:EISSN:1423-0356 |
op_rights |
info:eu-repo/semantics/closedAccess |
op_doi |
https://doi.org/10.1159/000442887 |
container_title |
Respiration |
container_volume |
91 |
container_issue |
1 |
container_start_page |
43 |
op_container_end_page |
55 |
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1799485833173008384 |