Morphological and Immunohistochemical Description of a Splenic Haemangioma in a Captive European Wolf ( Canis lupus lupus ) and a Review of the Current Literature
Neoplastic diseases are rarely described in wild carnivores; only a few reports have been published on this topic. Here, we describe the histological and immunohistochemical features of a haemangioma in the spleen of a grey wolf ( Canis lupus lupus ) and we compare the results with the dog ( Canis l...
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Language: | English |
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2020
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Online Access: | https://livrepository.liverpool.ac.uk/3096882/ https://doi.org/10.3390/vetsci7030102 https://livrepository.liverpool.ac.uk/3096882/1/VET%20SCI%20Splenic%20haemangioma%20wolf.pdf |
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ftunivliverpool:oai:livrepository.liverpool.ac.uk:3096882 2024-09-09T19:35:19+00:00 Morphological and Immunohistochemical Description of a Splenic Haemangioma in a Captive European Wolf ( Canis lupus lupus ) and a Review of the Current Literature Monne Rodriguez, Josep Maria Morandi, Federico Cavicchio, Paolo Poli, Alessandro Verin, Ranieri 2020 text https://livrepository.liverpool.ac.uk/3096882/ https://doi.org/10.3390/vetsci7030102 https://livrepository.liverpool.ac.uk/3096882/1/VET%20SCI%20Splenic%20haemangioma%20wolf.pdf en eng eng MDPI AG https://livrepository.liverpool.ac.uk/3096882/1/VET%20SCI%20Splenic%20haemangioma%20wolf.pdf Monne Rodriguez, Josep Maria, Morandi, Federico, Cavicchio, Paolo, Poli, Alessandro and Verin, Ranieri orcid:0000-0001-9366-5682 (2020) Morphological and Immunohistochemical Description of a Splenic Haemangioma in a Captive European Wolf ( Canis lupus lupus ) and a Review of the Current Literature. VETERINARY SCIENCES, 7 (3). E102-. Article NonPeerReviewed 2020 ftunivliverpool https://doi.org/10.3390/vetsci7030102 2024-07-08T14:17:39Z Neoplastic diseases are rarely described in wild carnivores; only a few reports have been published on this topic. Here, we describe the histological and immunohistochemical features of a haemangioma in the spleen of a grey wolf ( Canis lupus lupus ) and we compare the results with the dog ( Canis lupus familiaris ). Additionally, we list the different publications found in the literature with neoplastic lesions in wolves. Our results show similar immunohistochemical features to dogs, in which neoplastic cells express Vimentin, von Willebrand factor, alpha smooth muscle actin antibody, vascular endothelial growth factor C and low vascular endothelial growth factor receptor 3. Toluidine blue special stain shows moderated increased numbers of mast cells infiltrating the tumor, a feature observed in benign vascular tumors in domestic dogs, but not in the malignant counterparts. To our knowledge, this is the first article describing the gross, histological and immunohistochemical features of a splenic haemangioma in a wolf. Article in Journal/Newspaper Canis lupus The University of Liverpool Repository Veterinary Sciences 7 3 102 |
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Open Polar |
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The University of Liverpool Repository |
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ftunivliverpool |
language |
English |
description |
Neoplastic diseases are rarely described in wild carnivores; only a few reports have been published on this topic. Here, we describe the histological and immunohistochemical features of a haemangioma in the spleen of a grey wolf ( Canis lupus lupus ) and we compare the results with the dog ( Canis lupus familiaris ). Additionally, we list the different publications found in the literature with neoplastic lesions in wolves. Our results show similar immunohistochemical features to dogs, in which neoplastic cells express Vimentin, von Willebrand factor, alpha smooth muscle actin antibody, vascular endothelial growth factor C and low vascular endothelial growth factor receptor 3. Toluidine blue special stain shows moderated increased numbers of mast cells infiltrating the tumor, a feature observed in benign vascular tumors in domestic dogs, but not in the malignant counterparts. To our knowledge, this is the first article describing the gross, histological and immunohistochemical features of a splenic haemangioma in a wolf. |
format |
Article in Journal/Newspaper |
author |
Monne Rodriguez, Josep Maria Morandi, Federico Cavicchio, Paolo Poli, Alessandro Verin, Ranieri |
spellingShingle |
Monne Rodriguez, Josep Maria Morandi, Federico Cavicchio, Paolo Poli, Alessandro Verin, Ranieri Morphological and Immunohistochemical Description of a Splenic Haemangioma in a Captive European Wolf ( Canis lupus lupus ) and a Review of the Current Literature |
author_facet |
Monne Rodriguez, Josep Maria Morandi, Federico Cavicchio, Paolo Poli, Alessandro Verin, Ranieri |
author_sort |
Monne Rodriguez, Josep Maria |
title |
Morphological and Immunohistochemical Description of a Splenic Haemangioma in a Captive European Wolf ( Canis lupus lupus ) and a Review of the Current Literature |
title_short |
Morphological and Immunohistochemical Description of a Splenic Haemangioma in a Captive European Wolf ( Canis lupus lupus ) and a Review of the Current Literature |
title_full |
Morphological and Immunohistochemical Description of a Splenic Haemangioma in a Captive European Wolf ( Canis lupus lupus ) and a Review of the Current Literature |
title_fullStr |
Morphological and Immunohistochemical Description of a Splenic Haemangioma in a Captive European Wolf ( Canis lupus lupus ) and a Review of the Current Literature |
title_full_unstemmed |
Morphological and Immunohistochemical Description of a Splenic Haemangioma in a Captive European Wolf ( Canis lupus lupus ) and a Review of the Current Literature |
title_sort |
morphological and immunohistochemical description of a splenic haemangioma in a captive european wolf ( canis lupus lupus ) and a review of the current literature |
publisher |
MDPI AG |
publishDate |
2020 |
url |
https://livrepository.liverpool.ac.uk/3096882/ https://doi.org/10.3390/vetsci7030102 https://livrepository.liverpool.ac.uk/3096882/1/VET%20SCI%20Splenic%20haemangioma%20wolf.pdf |
genre |
Canis lupus |
genre_facet |
Canis lupus |
op_relation |
https://livrepository.liverpool.ac.uk/3096882/1/VET%20SCI%20Splenic%20haemangioma%20wolf.pdf Monne Rodriguez, Josep Maria, Morandi, Federico, Cavicchio, Paolo, Poli, Alessandro and Verin, Ranieri orcid:0000-0001-9366-5682 (2020) Morphological and Immunohistochemical Description of a Splenic Haemangioma in a Captive European Wolf ( Canis lupus lupus ) and a Review of the Current Literature. VETERINARY SCIENCES, 7 (3). E102-. |
op_doi |
https://doi.org/10.3390/vetsci7030102 |
container_title |
Veterinary Sciences |
container_volume |
7 |
container_issue |
3 |
container_start_page |
102 |
_version_ |
1809904699643527168 |