Quantification of maxillary ontogenetic processes using surface histology and geometric morphometrics
This thesis investigates the variability of ontogenetic maxillary bone modeling patterns in humans (Homo sapiens) and chimpanzees (Pan troglodytes). Along with sutural growth, bone modeling is the microscopic process by which bones grow in size and model their shape. It results from the simultaneous...
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ftunivleipzig:oai:qucosa:de:qucosa:75913 2023-09-05T13:19:56+02:00 Quantification of maxillary ontogenetic processes using surface histology and geometric morphometrics Schuh, Alexandra Universität Leipzig 2020-11-25 https://nbn-resolving.org/urn:nbn:de:bsz:15-qucosa2-759133 https://ul.qucosa.de/id/qucosa%3A75913 https://ul.qucosa.de/api/qucosa%3A75913/attachment/ATT-0/ eng eng urn:nbn:de:bsz:15-qucosa2-759133 https://ul.qucosa.de/id/qucosa%3A75913 https://ul.qucosa.de/api/qucosa%3A75913/attachment/ATT-0/ info:eu-repo/semantics/openAccess Bone modeling ontogeny facial evolution info:eu-repo/classification/ddc/570 ddc:570 info:eu-repo/semantics/acceptedVersion doc-type:doctoralThesis info:eu-repo/semantics/doctoralThesis doc-type:Text 2020 ftunivleipzig 2023-08-11T13:58:47Z This thesis investigates the variability of ontogenetic maxillary bone modeling patterns in humans (Homo sapiens) and chimpanzees (Pan troglodytes). Along with sutural growth, bone modeling is the microscopic process by which bones grow in size and model their shape. It results from the simultaneous cellular activities of bone formation (produced by the osteoblasts) and bone resorption (produced by the osteoclasts) on bone surfaces. The study of these activities can bring new insights into our understanding of maxillary, and, more generally, facial ontogeny. However, bone modeling variability remains poorly understood. Using surface histology, we developed quantitative methods to objectively compare and visualize bone modeling patterns. In parallel, geometric morphometric methods were used to capture and quantify maxillary shape changes. Both methods were used for the first time together in an integrative approach. A large sample of H. sapiens individuals ranging from birth to adulthood, and originating from three geographically distinct areas (Greenland, Western Europe and South Africa), was used to infer the variation in maxillary bone modeling at the intraspecific level. We found that human populations express similar bone modeling patterns, with only subtle differences in the location of bone resorption. Moreover, differences in developmental trajectories were identified. This suggests that population differences in maxillary morphology stem from changes in timing and/or rates of the osteoblastic and osteoclastic activities. Adult individuals show similar maxillary bone modeling patterns to subadults, with both cellular activities expressed at reduced intensities. All human populations express high amounts of bone resorption throughout ontogeny, and high inter-individual variation. In contrast, we find low amounts of bone resorption and a low inter-individual variation in chimpanzees, which results in the anterior projection of their maxilla. In chimpanzees, resorption is predominant in the premaxilla, which ... Doctoral or Postdoctoral Thesis Greenland Universität Leipzig: Qucosa Greenland |
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Universität Leipzig: Qucosa |
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English |
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Bone modeling ontogeny facial evolution info:eu-repo/classification/ddc/570 ddc:570 |
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Bone modeling ontogeny facial evolution info:eu-repo/classification/ddc/570 ddc:570 Schuh, Alexandra Quantification of maxillary ontogenetic processes using surface histology and geometric morphometrics |
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Bone modeling ontogeny facial evolution info:eu-repo/classification/ddc/570 ddc:570 |
description |
This thesis investigates the variability of ontogenetic maxillary bone modeling patterns in humans (Homo sapiens) and chimpanzees (Pan troglodytes). Along with sutural growth, bone modeling is the microscopic process by which bones grow in size and model their shape. It results from the simultaneous cellular activities of bone formation (produced by the osteoblasts) and bone resorption (produced by the osteoclasts) on bone surfaces. The study of these activities can bring new insights into our understanding of maxillary, and, more generally, facial ontogeny. However, bone modeling variability remains poorly understood. Using surface histology, we developed quantitative methods to objectively compare and visualize bone modeling patterns. In parallel, geometric morphometric methods were used to capture and quantify maxillary shape changes. Both methods were used for the first time together in an integrative approach. A large sample of H. sapiens individuals ranging from birth to adulthood, and originating from three geographically distinct areas (Greenland, Western Europe and South Africa), was used to infer the variation in maxillary bone modeling at the intraspecific level. We found that human populations express similar bone modeling patterns, with only subtle differences in the location of bone resorption. Moreover, differences in developmental trajectories were identified. This suggests that population differences in maxillary morphology stem from changes in timing and/or rates of the osteoblastic and osteoclastic activities. Adult individuals show similar maxillary bone modeling patterns to subadults, with both cellular activities expressed at reduced intensities. All human populations express high amounts of bone resorption throughout ontogeny, and high inter-individual variation. In contrast, we find low amounts of bone resorption and a low inter-individual variation in chimpanzees, which results in the anterior projection of their maxilla. In chimpanzees, resorption is predominant in the premaxilla, which ... |
author2 |
Universität Leipzig |
format |
Doctoral or Postdoctoral Thesis |
author |
Schuh, Alexandra |
author_facet |
Schuh, Alexandra |
author_sort |
Schuh, Alexandra |
title |
Quantification of maxillary ontogenetic processes using surface histology and geometric morphometrics |
title_short |
Quantification of maxillary ontogenetic processes using surface histology and geometric morphometrics |
title_full |
Quantification of maxillary ontogenetic processes using surface histology and geometric morphometrics |
title_fullStr |
Quantification of maxillary ontogenetic processes using surface histology and geometric morphometrics |
title_full_unstemmed |
Quantification of maxillary ontogenetic processes using surface histology and geometric morphometrics |
title_sort |
quantification of maxillary ontogenetic processes using surface histology and geometric morphometrics |
publishDate |
2020 |
url |
https://nbn-resolving.org/urn:nbn:de:bsz:15-qucosa2-759133 https://ul.qucosa.de/id/qucosa%3A75913 https://ul.qucosa.de/api/qucosa%3A75913/attachment/ATT-0/ |
geographic |
Greenland |
geographic_facet |
Greenland |
genre |
Greenland |
genre_facet |
Greenland |
op_relation |
urn:nbn:de:bsz:15-qucosa2-759133 https://ul.qucosa.de/id/qucosa%3A75913 https://ul.qucosa.de/api/qucosa%3A75913/attachment/ATT-0/ |
op_rights |
info:eu-repo/semantics/openAccess |
_version_ |
1776200703836946432 |