Acylation stimulating protein is higher in Inuit from Nunavik compared to a southern Quebec population
Objectives. The Inuit of Nunavik in northern Quebec have a lower risk for ischemic heart disease (IHD) compared to Caucasian populations. Acylation stimulating protein (ASP), which is involved in the storage of dietary fat, may play a role. The objective of the study was to determine plasma concentr...
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International Association of Circumpolar Health Publishers
2020
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ftunivlavalcorp:oai:corpus.ulaval.ca:20.500.11794/39873 2024-09-09T19:48:09+00:00 Acylation stimulating protein is higher in Inuit from Nunavik compared to a southern Quebec population Smith, Jessica Julien, Pierre Dewailly, Éric Cianflone, Katherine M. Vohl, Marie-Claude Chateau-Degat, Marie-Ludivine Québec (Province) 2020-07-28T16:34:21Z application/pdf https://hdl.handle.net/20.500.11794/39873 eng eng International Association of Circumpolar Health Publishers 1239-9736 http://hdl.handle.net/20.500.11794/39873 10.3402/ijch.v68i5.17385. 20044961 http://purl.org/coar/access_right/c_abf2 Acylation stimulating protein (ASP) Inuit Retinol Metabolic syndrome Acylation Vitamine A Syndrome métabolique Inuits -- Santé et hygiène Cœur -- Maladies -- Facteurs de risque article de recherche COAR1_1::Texte::Périodique::Revue::Contribution à un journal::Article::Article de recherche 2020 ftunivlavalcorp https://doi.org/20.500.11794/39873 2024-06-17T23:42:35Z Objectives. The Inuit of Nunavik in northern Quebec have a lower risk for ischemic heart disease (IHD) compared to Caucasian populations. Acylation stimulating protein (ASP), which is involved in the storage of dietary fat, may play a role. The objective of the study was to determine plasma concentration of ASP in an Inuit and a southern Quebec Caucasian population. Study design. This is a cross-sectional study evaluating the relationship between ASP and dietary factors, such as retinol, whose intake is higher in the Inuit. As well, concentrations of ASP were evaluated in relationship to components of the metabolic syndrome. Methods. Medical history was collected via a questionnaire and anthropometric measurements and blood samples were collected. Results. ASP was significantly higher in both the Inuit men and women compared to Caucasian men (66.1±4.1 nM vs 27.5±2.5 nM, p<0.0001) and women (71.8±3.8 nM vs 29.4±1.3 nM, p<0.0001). In addition, ASP significantly correlated with total retinol (r=0.17, p=0.02) and free retinol (r=0.15, p=0.04) in Inuit men but not with other distinctive dietary markers such as omega-3 fatty acids. Conclusions. Inuit men and women have higher ASP which was unrelated to the number of risk factors for IHD that were present. Other/Unknown Material inuit inuits Nunavik Université Laval: CorpusUL Nunavik |
institution |
Open Polar |
collection |
Université Laval: CorpusUL |
op_collection_id |
ftunivlavalcorp |
language |
English |
topic |
Acylation stimulating protein (ASP) Inuit Retinol Metabolic syndrome Acylation Vitamine A Syndrome métabolique Inuits -- Santé et hygiène Cœur -- Maladies -- Facteurs de risque |
spellingShingle |
Acylation stimulating protein (ASP) Inuit Retinol Metabolic syndrome Acylation Vitamine A Syndrome métabolique Inuits -- Santé et hygiène Cœur -- Maladies -- Facteurs de risque Smith, Jessica Julien, Pierre Dewailly, Éric Cianflone, Katherine M. Vohl, Marie-Claude Chateau-Degat, Marie-Ludivine Acylation stimulating protein is higher in Inuit from Nunavik compared to a southern Quebec population |
topic_facet |
Acylation stimulating protein (ASP) Inuit Retinol Metabolic syndrome Acylation Vitamine A Syndrome métabolique Inuits -- Santé et hygiène Cœur -- Maladies -- Facteurs de risque |
description |
Objectives. The Inuit of Nunavik in northern Quebec have a lower risk for ischemic heart disease (IHD) compared to Caucasian populations. Acylation stimulating protein (ASP), which is involved in the storage of dietary fat, may play a role. The objective of the study was to determine plasma concentration of ASP in an Inuit and a southern Quebec Caucasian population. Study design. This is a cross-sectional study evaluating the relationship between ASP and dietary factors, such as retinol, whose intake is higher in the Inuit. As well, concentrations of ASP were evaluated in relationship to components of the metabolic syndrome. Methods. Medical history was collected via a questionnaire and anthropometric measurements and blood samples were collected. Results. ASP was significantly higher in both the Inuit men and women compared to Caucasian men (66.1±4.1 nM vs 27.5±2.5 nM, p<0.0001) and women (71.8±3.8 nM vs 29.4±1.3 nM, p<0.0001). In addition, ASP significantly correlated with total retinol (r=0.17, p=0.02) and free retinol (r=0.15, p=0.04) in Inuit men but not with other distinctive dietary markers such as omega-3 fatty acids. Conclusions. Inuit men and women have higher ASP which was unrelated to the number of risk factors for IHD that were present. |
format |
Other/Unknown Material |
author |
Smith, Jessica Julien, Pierre Dewailly, Éric Cianflone, Katherine M. Vohl, Marie-Claude Chateau-Degat, Marie-Ludivine |
author_facet |
Smith, Jessica Julien, Pierre Dewailly, Éric Cianflone, Katherine M. Vohl, Marie-Claude Chateau-Degat, Marie-Ludivine |
author_sort |
Smith, Jessica |
title |
Acylation stimulating protein is higher in Inuit from Nunavik compared to a southern Quebec population |
title_short |
Acylation stimulating protein is higher in Inuit from Nunavik compared to a southern Quebec population |
title_full |
Acylation stimulating protein is higher in Inuit from Nunavik compared to a southern Quebec population |
title_fullStr |
Acylation stimulating protein is higher in Inuit from Nunavik compared to a southern Quebec population |
title_full_unstemmed |
Acylation stimulating protein is higher in Inuit from Nunavik compared to a southern Quebec population |
title_sort |
acylation stimulating protein is higher in inuit from nunavik compared to a southern quebec population |
publisher |
International Association of Circumpolar Health Publishers |
publishDate |
2020 |
url |
https://hdl.handle.net/20.500.11794/39873 |
op_coverage |
Québec (Province) |
geographic |
Nunavik |
geographic_facet |
Nunavik |
genre |
inuit inuits Nunavik |
genre_facet |
inuit inuits Nunavik |
op_relation |
1239-9736 http://hdl.handle.net/20.500.11794/39873 10.3402/ijch.v68i5.17385. 20044961 |
op_rights |
http://purl.org/coar/access_right/c_abf2 |
op_doi |
https://doi.org/20.500.11794/39873 |
_version_ |
1809917514114662400 |