Does prenatal methylmercury exposure from fish consumption affect blood pressure in childhood?
INTRODUCTION: Prenatal exposure to organic methylmercury (MeHg) from seafood consumption has been reported to increase children's blood pressure (BP). A report from the Faroe Islands noted significantly increased diastolic and systolic BP in 7-year-old children as prenatal MeHg exposure increas...
Published in: | NeuroToxicology |
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Online Access: | https://serval.unil.ch/notice/serval:BIB_FCABC1E23C21 https://doi.org/10.1016/j.neuro.2007.06.002 https://serval.unil.ch/resource/serval:BIB_FCABC1E23C21.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_FCABC1E23C213 |
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ftunivlausanne:oai:serval.unil.ch:BIB_FCABC1E23C21 2024-02-11T10:03:42+01:00 Does prenatal methylmercury exposure from fish consumption affect blood pressure in childhood? Thurston Sally, W. Bovet, Pascal Myers Gary, J. Davidson Philip, W. Georger Lesley, A. Shamlaye, Conrad Clarkson Thomas, W. 2007 application/pdf https://serval.unil.ch/notice/serval:BIB_FCABC1E23C21 https://doi.org/10.1016/j.neuro.2007.06.002 https://serval.unil.ch/resource/serval:BIB_FCABC1E23C21.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_FCABC1E23C213 eng eng info:eu-repo/semantics/altIdentifier/doi/10.1016/j.neuro.2007.06.002 info:eu-repo/semantics/altIdentifier/pmid/17659343 info:eu-repo/semantics/altIdentifier/pissn/0161-813X info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_FCABC1E23C213 https://serval.unil.ch/notice/serval:BIB_FCABC1E23C21 doi:10.1016/j.neuro.2007.06.002 https://serval.unil.ch/resource/serval:BIB_FCABC1E23C21.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_FCABC1E23C213 info:eu-repo/semantics/openAccess Copying allowed only for non-profit organizations https://serval.unil.ch/disclaimer Neurotoxicology, vol. 28, no. 5, pp. 924-930 Adolescent Adult Animals Blood Pressure Blood Pressure/drug effects Child Diet Diet/adverse effects Double-Blind Method Female Fishes Humans Longitudinal Studies Male Methylmercury Compounds Methylmercury Compounds/toxicity Models Statistical Pregnancy Prenatal Exposure Delayed Effects Prenatal Exposure Delayed Effects/physiopathology Prospective Studies Regression Analysis Seafood Seafood/adverse effects Seafood/analysis Sex Factors Seychelles info:eu-repo/semantics/article article info:eu-repo/semantics/submittedVersion 2007 ftunivlausanne https://doi.org/10.1016/j.neuro.2007.06.002 2024-01-22T00:54:08Z INTRODUCTION: Prenatal exposure to organic methylmercury (MeHg) from seafood consumption has been reported to increase children's blood pressure (BP). A report from the Faroe Islands noted significantly increased diastolic and systolic BP in 7-year-old children as prenatal MeHg exposure increased. The Faroese diet includes sea mammals that contain MeHg, cadmium, and other pollutants. We examined this relationship in the Seychelles Islands to determine if it was present in a society exposed primarily to MeHg from consuming ocean fish. METHODS: We obtained BP at ages 12 and 15 years on children with known prenatal MeHg exposure enrolled in the Seychelles Child Development Study (SCDS). We examined the association between prenatal MeHg exposure and BP using longitudinal models and linear regression adjusted for relevant covariates. RESULTS: Blood pressure at both ages was associated with BMI, height and maternal hypertension during pregnancy as expected. No association between prenatal MeHg exposure and BP was present in girls at either age or in either sex at age 12 years. At age 15 years diastolic BP in boys increased with increasing prenatal MeHg exposure, while systolic BP was unaffected. SUMMARY: It is unclear whether the association between prenatal MeHg exposure and diastolic BP seen in 15-year-old boys is of biological significance or if it is a chance finding. However, the finding is intriguing and deserves further study. Article in Journal/Newspaper Faroe Islands Université de Lausanne (UNIL): Serval - Serveur académique lausannois Faroe Islands NeuroToxicology 28 5 924 930 |
institution |
Open Polar |
collection |
Université de Lausanne (UNIL): Serval - Serveur académique lausannois |
op_collection_id |
ftunivlausanne |
language |
English |
topic |
Adolescent Adult Animals Blood Pressure Blood Pressure/drug effects Child Diet Diet/adverse effects Double-Blind Method Female Fishes Humans Longitudinal Studies Male Methylmercury Compounds Methylmercury Compounds/toxicity Models Statistical Pregnancy Prenatal Exposure Delayed Effects Prenatal Exposure Delayed Effects/physiopathology Prospective Studies Regression Analysis Seafood Seafood/adverse effects Seafood/analysis Sex Factors Seychelles |
spellingShingle |
Adolescent Adult Animals Blood Pressure Blood Pressure/drug effects Child Diet Diet/adverse effects Double-Blind Method Female Fishes Humans Longitudinal Studies Male Methylmercury Compounds Methylmercury Compounds/toxicity Models Statistical Pregnancy Prenatal Exposure Delayed Effects Prenatal Exposure Delayed Effects/physiopathology Prospective Studies Regression Analysis Seafood Seafood/adverse effects Seafood/analysis Sex Factors Seychelles Thurston Sally, W. Bovet, Pascal Myers Gary, J. Davidson Philip, W. Georger Lesley, A. Shamlaye, Conrad Clarkson Thomas, W. Does prenatal methylmercury exposure from fish consumption affect blood pressure in childhood? |
topic_facet |
Adolescent Adult Animals Blood Pressure Blood Pressure/drug effects Child Diet Diet/adverse effects Double-Blind Method Female Fishes Humans Longitudinal Studies Male Methylmercury Compounds Methylmercury Compounds/toxicity Models Statistical Pregnancy Prenatal Exposure Delayed Effects Prenatal Exposure Delayed Effects/physiopathology Prospective Studies Regression Analysis Seafood Seafood/adverse effects Seafood/analysis Sex Factors Seychelles |
description |
INTRODUCTION: Prenatal exposure to organic methylmercury (MeHg) from seafood consumption has been reported to increase children's blood pressure (BP). A report from the Faroe Islands noted significantly increased diastolic and systolic BP in 7-year-old children as prenatal MeHg exposure increased. The Faroese diet includes sea mammals that contain MeHg, cadmium, and other pollutants. We examined this relationship in the Seychelles Islands to determine if it was present in a society exposed primarily to MeHg from consuming ocean fish. METHODS: We obtained BP at ages 12 and 15 years on children with known prenatal MeHg exposure enrolled in the Seychelles Child Development Study (SCDS). We examined the association between prenatal MeHg exposure and BP using longitudinal models and linear regression adjusted for relevant covariates. RESULTS: Blood pressure at both ages was associated with BMI, height and maternal hypertension during pregnancy as expected. No association between prenatal MeHg exposure and BP was present in girls at either age or in either sex at age 12 years. At age 15 years diastolic BP in boys increased with increasing prenatal MeHg exposure, while systolic BP was unaffected. SUMMARY: It is unclear whether the association between prenatal MeHg exposure and diastolic BP seen in 15-year-old boys is of biological significance or if it is a chance finding. However, the finding is intriguing and deserves further study. |
format |
Article in Journal/Newspaper |
author |
Thurston Sally, W. Bovet, Pascal Myers Gary, J. Davidson Philip, W. Georger Lesley, A. Shamlaye, Conrad Clarkson Thomas, W. |
author_facet |
Thurston Sally, W. Bovet, Pascal Myers Gary, J. Davidson Philip, W. Georger Lesley, A. Shamlaye, Conrad Clarkson Thomas, W. |
author_sort |
Thurston Sally, W. |
title |
Does prenatal methylmercury exposure from fish consumption affect blood pressure in childhood? |
title_short |
Does prenatal methylmercury exposure from fish consumption affect blood pressure in childhood? |
title_full |
Does prenatal methylmercury exposure from fish consumption affect blood pressure in childhood? |
title_fullStr |
Does prenatal methylmercury exposure from fish consumption affect blood pressure in childhood? |
title_full_unstemmed |
Does prenatal methylmercury exposure from fish consumption affect blood pressure in childhood? |
title_sort |
does prenatal methylmercury exposure from fish consumption affect blood pressure in childhood? |
publishDate |
2007 |
url |
https://serval.unil.ch/notice/serval:BIB_FCABC1E23C21 https://doi.org/10.1016/j.neuro.2007.06.002 https://serval.unil.ch/resource/serval:BIB_FCABC1E23C21.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_FCABC1E23C213 |
geographic |
Faroe Islands |
geographic_facet |
Faroe Islands |
genre |
Faroe Islands |
genre_facet |
Faroe Islands |
op_source |
Neurotoxicology, vol. 28, no. 5, pp. 924-930 |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.neuro.2007.06.002 info:eu-repo/semantics/altIdentifier/pmid/17659343 info:eu-repo/semantics/altIdentifier/pissn/0161-813X info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_FCABC1E23C213 https://serval.unil.ch/notice/serval:BIB_FCABC1E23C21 doi:10.1016/j.neuro.2007.06.002 https://serval.unil.ch/resource/serval:BIB_FCABC1E23C21.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_FCABC1E23C213 |
op_rights |
info:eu-repo/semantics/openAccess Copying allowed only for non-profit organizations https://serval.unil.ch/disclaimer |
op_doi |
https://doi.org/10.1016/j.neuro.2007.06.002 |
container_title |
NeuroToxicology |
container_volume |
28 |
container_issue |
5 |
container_start_page |
924 |
op_container_end_page |
930 |
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1790600021141356544 |