Longevity differs among sexes but is not affected by repeated immune activation in voles (Microtus arvalis)
Investment of resources in immune defences, despite obvious short-term benefits, may be detrimental to long-term maintenance and thus decrease longevity in absence of parasites. In addition, females and males may differ in immune investment and intrinsic longevity because they are subjected to diffe...
Published in: | Biological Journal of the Linnean Society |
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Format: | Article in Journal/Newspaper |
Language: | English |
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2009
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Online Access: | https://serval.unil.ch/notice/serval:BIB_C0D24004FEA5 https://doi.org/10.1111/j.1095-8312.2009.01216.x https://serval.unil.ch/resource/serval:BIB_C0D24004FEA5.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_C0D24004FEA56 |
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ftunivlausanne:oai:serval.unil.ch:BIB_C0D24004FEA5 2024-02-11T10:05:50+01:00 Longevity differs among sexes but is not affected by repeated immune activation in voles (Microtus arvalis) Devevey, G. Chapuisat, M. Christe, P. 2009 application/pdf https://serval.unil.ch/notice/serval:BIB_C0D24004FEA5 https://doi.org/10.1111/j.1095-8312.2009.01216.x https://serval.unil.ch/resource/serval:BIB_C0D24004FEA5.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_C0D24004FEA56 eng eng info:eu-repo/semantics/altIdentifier/doi/10.1111/j.1095-8312.2009.01216.x info:eu-repo/semantics/altIdentifier/pissn/0024-4066 info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_C0D24004FEA56 https://serval.unil.ch/notice/serval:BIB_C0D24004FEA5 doi:10.1111/j.1095-8312.2009.01216.x https://serval.unil.ch/resource/serval:BIB_C0D24004FEA5.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_C0D24004FEA56 info:eu-repo/semantics/openAccess Copying allowed only for non-profit organizations https://serval.unil.ch/disclaimer Biological Journal of the Linnean Society, vol. 97, no. 2, pp. 328-333 ageing cost of immunity intrinsic mortality keyhole limpet haemocyanin lifespan sex-biased longevity info:eu-repo/semantics/article article info:eu-repo/semantics/publishedVersion 2009 ftunivlausanne https://doi.org/10.1111/j.1095-8312.2009.01216.x 2024-01-22T01:00:03Z Investment of resources in immune defences, despite obvious short-term benefits, may be detrimental to long-term maintenance and thus decrease longevity in absence of parasites. In addition, females and males may differ in immune investment and intrinsic longevity because they are subjected to different degrees of sexual competition and extrinsic mortality. In order to test if sex-specific investment in mounting an immune response reduced longevity, we compared the longevity of captive male and female common voles Microtus arvalis regularly challenged with keyhole limpet haemocyanin, an antigen which elicits the production of antibodies, to the longevity of voles injected with the corresponding antigen-free buffer (phosphate-buffered saline). Injections were repeated every 28 days to mimic a chronic infection. The magnitude of immune response did not vary between males and females and did not affect longevity. Overall, females lived longer than males, independently of the immune challenge. Thus, the long-term costs of immunity seem small in voles. The longevity pattern is consistent with the prediction that male-biased predation or parasitism in the wild causes reduced intrinsic lifespan, but this reduction is not mediated by a decrease in male immunity Article in Journal/Newspaper Microtus arvalis Université de Lausanne (UNIL): Serval - Serveur académique lausannois Keyhole ENVELOPE(-67.338,-67.338,-68.785,-68.785) Biological Journal of the Linnean Society 97 2 328 333 |
institution |
Open Polar |
collection |
Université de Lausanne (UNIL): Serval - Serveur académique lausannois |
op_collection_id |
ftunivlausanne |
language |
English |
topic |
ageing cost of immunity intrinsic mortality keyhole limpet haemocyanin lifespan sex-biased longevity |
spellingShingle |
ageing cost of immunity intrinsic mortality keyhole limpet haemocyanin lifespan sex-biased longevity Devevey, G. Chapuisat, M. Christe, P. Longevity differs among sexes but is not affected by repeated immune activation in voles (Microtus arvalis) |
topic_facet |
ageing cost of immunity intrinsic mortality keyhole limpet haemocyanin lifespan sex-biased longevity |
description |
Investment of resources in immune defences, despite obvious short-term benefits, may be detrimental to long-term maintenance and thus decrease longevity in absence of parasites. In addition, females and males may differ in immune investment and intrinsic longevity because they are subjected to different degrees of sexual competition and extrinsic mortality. In order to test if sex-specific investment in mounting an immune response reduced longevity, we compared the longevity of captive male and female common voles Microtus arvalis regularly challenged with keyhole limpet haemocyanin, an antigen which elicits the production of antibodies, to the longevity of voles injected with the corresponding antigen-free buffer (phosphate-buffered saline). Injections were repeated every 28 days to mimic a chronic infection. The magnitude of immune response did not vary between males and females and did not affect longevity. Overall, females lived longer than males, independently of the immune challenge. Thus, the long-term costs of immunity seem small in voles. The longevity pattern is consistent with the prediction that male-biased predation or parasitism in the wild causes reduced intrinsic lifespan, but this reduction is not mediated by a decrease in male immunity |
format |
Article in Journal/Newspaper |
author |
Devevey, G. Chapuisat, M. Christe, P. |
author_facet |
Devevey, G. Chapuisat, M. Christe, P. |
author_sort |
Devevey, G. |
title |
Longevity differs among sexes but is not affected by repeated immune activation in voles (Microtus arvalis) |
title_short |
Longevity differs among sexes but is not affected by repeated immune activation in voles (Microtus arvalis) |
title_full |
Longevity differs among sexes but is not affected by repeated immune activation in voles (Microtus arvalis) |
title_fullStr |
Longevity differs among sexes but is not affected by repeated immune activation in voles (Microtus arvalis) |
title_full_unstemmed |
Longevity differs among sexes but is not affected by repeated immune activation in voles (Microtus arvalis) |
title_sort |
longevity differs among sexes but is not affected by repeated immune activation in voles (microtus arvalis) |
publishDate |
2009 |
url |
https://serval.unil.ch/notice/serval:BIB_C0D24004FEA5 https://doi.org/10.1111/j.1095-8312.2009.01216.x https://serval.unil.ch/resource/serval:BIB_C0D24004FEA5.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_C0D24004FEA56 |
long_lat |
ENVELOPE(-67.338,-67.338,-68.785,-68.785) |
geographic |
Keyhole |
geographic_facet |
Keyhole |
genre |
Microtus arvalis |
genre_facet |
Microtus arvalis |
op_source |
Biological Journal of the Linnean Society, vol. 97, no. 2, pp. 328-333 |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1111/j.1095-8312.2009.01216.x info:eu-repo/semantics/altIdentifier/pissn/0024-4066 info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_C0D24004FEA56 https://serval.unil.ch/notice/serval:BIB_C0D24004FEA5 doi:10.1111/j.1095-8312.2009.01216.x https://serval.unil.ch/resource/serval:BIB_C0D24004FEA5.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_C0D24004FEA56 |
op_rights |
info:eu-repo/semantics/openAccess Copying allowed only for non-profit organizations https://serval.unil.ch/disclaimer |
op_doi |
https://doi.org/10.1111/j.1095-8312.2009.01216.x |
container_title |
Biological Journal of the Linnean Society |
container_volume |
97 |
container_issue |
2 |
container_start_page |
328 |
op_container_end_page |
333 |
_version_ |
1790603029705129984 |