Chikungunya Virus Infection: Why Should U.S. Geriatricians Be Aware of It?
Chikungunya virus (CHIKV) was until recently perceived only as a tropical disease. Since the first report of a case in Saint Martin Island in 2013, it has spread to South, Central, and North America. The first local transmission in the continental United States was reported in Florida in July 2014....
Published in: | Journal of the American Geriatrics Society |
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ftunivlausanne:oai:serval.unil.ch:BIB_7AC43F491DC1 2024-02-11T10:05:44+01:00 Chikungunya Virus Infection: Why Should U.S. Geriatricians Be Aware of It? Lang, P.O. Loulergue, P. Aspinall, R. 2017-11 https://serval.unil.ch/notice/serval:BIB_7AC43F491DC1 https://doi.org/10.1111/jgs.15104 eng eng info:eu-repo/semantics/altIdentifier/doi/10.1111/jgs.15104 info:eu-repo/semantics/altIdentifier/pmid/28940385 info:eu-repo/semantics/altIdentifier/eissn/1532-5415 https://serval.unil.ch/notice/serval:BIB_7AC43F491DC1 doi:10.1111/jgs.15104 urn:issn:0002-8614 Journal of the American Geriatrics Society, vol. 65, no. 11, pp. 2529-2534 Aged 80 and over Chikungunya Fever/epidemiology Chikungunya Fever/prevention & control Disease Outbreaks/prevention & control Female Geriatric Assessment/statistics & numerical data Geriatricians/standards Humans Male Practice Patterns Physicians'/standards United States aged people chikungunya virus infection clinical forms info:eu-repo/semantics/review article 2017 ftunivlausanne https://doi.org/10.1111/jgs.15104 2024-01-22T01:05:54Z Chikungunya virus (CHIKV) was until recently perceived only as a tropical disease. Since the first report of a case in Saint Martin Island in 2013, it has spread to South, Central, and North America. The first local transmission in the continental United States was reported in Florida in July 2014. CHIV infection is known to cause debilitating rheumatologic disease. Older adults are particularly susceptible to severe and chronic infection. Without an effective vaccine and antiviral therapy to prevent and control CHIKV, U.S. geriatricians could soon be confronted with major clinical, functional, and therapeutic challenges. After a general overview of CHIKV infection, this review will examine reasons why it has become such a threat to the United States and consider factors that contribute to the greater burden and effect of this disease in elderly adults. Consideration will be given to how aging and immunosenescence may contribute to CHIKV's atypical and more-severe clinical features in older adults. This review concludes with possible therapeutic approaches that best fit the unique needs of older adults, especially with regard to multimorbidity and polypharmacy. Article in Journal/Newspaper Martin Island Université de Lausanne (UNIL): Serval - Serveur académique lausannois Martin Island ENVELOPE(56.967,56.967,-66.733,-66.733) Journal of the American Geriatrics Society 65 11 2529 2534 |
institution |
Open Polar |
collection |
Université de Lausanne (UNIL): Serval - Serveur académique lausannois |
op_collection_id |
ftunivlausanne |
language |
English |
topic |
Aged 80 and over Chikungunya Fever/epidemiology Chikungunya Fever/prevention & control Disease Outbreaks/prevention & control Female Geriatric Assessment/statistics & numerical data Geriatricians/standards Humans Male Practice Patterns Physicians'/standards United States aged people chikungunya virus infection clinical forms |
spellingShingle |
Aged 80 and over Chikungunya Fever/epidemiology Chikungunya Fever/prevention & control Disease Outbreaks/prevention & control Female Geriatric Assessment/statistics & numerical data Geriatricians/standards Humans Male Practice Patterns Physicians'/standards United States aged people chikungunya virus infection clinical forms Lang, P.O. Loulergue, P. Aspinall, R. Chikungunya Virus Infection: Why Should U.S. Geriatricians Be Aware of It? |
topic_facet |
Aged 80 and over Chikungunya Fever/epidemiology Chikungunya Fever/prevention & control Disease Outbreaks/prevention & control Female Geriatric Assessment/statistics & numerical data Geriatricians/standards Humans Male Practice Patterns Physicians'/standards United States aged people chikungunya virus infection clinical forms |
description |
Chikungunya virus (CHIKV) was until recently perceived only as a tropical disease. Since the first report of a case in Saint Martin Island in 2013, it has spread to South, Central, and North America. The first local transmission in the continental United States was reported in Florida in July 2014. CHIV infection is known to cause debilitating rheumatologic disease. Older adults are particularly susceptible to severe and chronic infection. Without an effective vaccine and antiviral therapy to prevent and control CHIKV, U.S. geriatricians could soon be confronted with major clinical, functional, and therapeutic challenges. After a general overview of CHIKV infection, this review will examine reasons why it has become such a threat to the United States and consider factors that contribute to the greater burden and effect of this disease in elderly adults. Consideration will be given to how aging and immunosenescence may contribute to CHIKV's atypical and more-severe clinical features in older adults. This review concludes with possible therapeutic approaches that best fit the unique needs of older adults, especially with regard to multimorbidity and polypharmacy. |
format |
Article in Journal/Newspaper |
author |
Lang, P.O. Loulergue, P. Aspinall, R. |
author_facet |
Lang, P.O. Loulergue, P. Aspinall, R. |
author_sort |
Lang, P.O. |
title |
Chikungunya Virus Infection: Why Should U.S. Geriatricians Be Aware of It? |
title_short |
Chikungunya Virus Infection: Why Should U.S. Geriatricians Be Aware of It? |
title_full |
Chikungunya Virus Infection: Why Should U.S. Geriatricians Be Aware of It? |
title_fullStr |
Chikungunya Virus Infection: Why Should U.S. Geriatricians Be Aware of It? |
title_full_unstemmed |
Chikungunya Virus Infection: Why Should U.S. Geriatricians Be Aware of It? |
title_sort |
chikungunya virus infection: why should u.s. geriatricians be aware of it? |
publishDate |
2017 |
url |
https://serval.unil.ch/notice/serval:BIB_7AC43F491DC1 https://doi.org/10.1111/jgs.15104 |
long_lat |
ENVELOPE(56.967,56.967,-66.733,-66.733) |
geographic |
Martin Island |
geographic_facet |
Martin Island |
genre |
Martin Island |
genre_facet |
Martin Island |
op_source |
Journal of the American Geriatrics Society, vol. 65, no. 11, pp. 2529-2534 |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1111/jgs.15104 info:eu-repo/semantics/altIdentifier/pmid/28940385 info:eu-repo/semantics/altIdentifier/eissn/1532-5415 https://serval.unil.ch/notice/serval:BIB_7AC43F491DC1 doi:10.1111/jgs.15104 urn:issn:0002-8614 |
op_doi |
https://doi.org/10.1111/jgs.15104 |
container_title |
Journal of the American Geriatrics Society |
container_volume |
65 |
container_issue |
11 |
container_start_page |
2529 |
op_container_end_page |
2534 |
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1790602885814288384 |