Stress cardiomyopathy in stranded cetaceans: a histological, histochemical and immunohistochemical study
BACKGROUND: Free-living cetaceans are exposed to a wide variety of stressful situations, including live stranding and interaction with human beings (capture myopathy), vessel strikes, and fishing activities (bycatch), which affect their wellbeing and potentially lead to stress cardiomyopathy (SCMP)....
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Online Access: | http://hdl.handle.net/10553/59990 https://doi.org/10.1136/vr.105562 |
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ftunivlaspalmas:oai:accedacris.ulpgc.es:10553/59990 2023-05-15T15:41:53+02:00 Stress cardiomyopathy in stranded cetaceans: a histological, histochemical and immunohistochemical study Câmara, Nakita Sierra, Eva Fernández-Maldonado, Carolina Espinosa de los Monteros, A. Arbelo, Manuel Fernández, Antonio Herráez, Pedro 57191486481 15742962600 55496133700 36928058400 6603561403 57212084410 57194503614 12624727 30396242 5009228 700159 667707 32111845 30335206 WOS:Camara, N WOS:Sierra, E WOS:Fernandez-Maldonado, C WOS:de los Monteros, AE WOS:Arbelo, M WOS:Fernandez, A WOS:Herraez, P 2019 http://hdl.handle.net/10553/59990 https://doi.org/10.1136/vr.105562 eng eng Veterinary Record 185 0042-4900 Scopus http://hdl.handle.net/10553/59990 doi:10.1136/vr.105562 85076325356 000503797400023 2042-7670 22 The Veterinary record [ISSN 0042-4900], v. 185 (22), p. 694 Investigación Takotsubo Cardiomyopathy Cardiac Troponin Capture Myopathy Beluga Whales Tako-Tsubo Pathology Features Disease Marker Death info:eu-repo/semantics/article Article 2019 ftunivlaspalmas https://doi.org/10.1136/vr.105562 2020-06-02T23:08:24Z BACKGROUND: Free-living cetaceans are exposed to a wide variety of stressful situations, including live stranding and interaction with human beings (capture myopathy), vessel strikes, and fishing activities (bycatch), which affect their wellbeing and potentially lead to stress cardiomyopathy (SCMP). METHODS: Here, the authors aimed to characterise SCMP of stranded cetaceans as an injury resulting from extreme stress responses, based on pathological analyses (histological, histochemical and immunohistochemical). Specifically, the authors examined heart samples from 67 cetaceans found ashore (48 live strandings, seven dead from ship collision and 12 dead from bycatch) on the coast of Spain, more specifically in the Canary Islands from 2000 to 2016 and Andalusia from 2011 to 2014. RESULTS: The microscopic findings were characterised by vascular changes, acute or subacute cardiac degenerative necrotic lesions, interstitial myoglobin globules, and infiltration of inflammatory cells. Immunohistochemically, cardiac troponin I, cardiac troponin C and myoglobin were depleted, along with fibrinogen being expressed in the degenerated/necrotic cardiomyocytes. A perivascular pattern was also identified and described in the damaged cardiomyocytes. CONCLUSIONS: This study advances current knowledge about the pathologies of cetaceans and their implications on conserving this group of animals by reducing mortality and enhancing their treatment and subsequent rehabilitation to the marine environment. 694 694 11 Article in Journal/Newspaper Beluga Beluga* Universidad de Las Palmas de Gran Canaria: Acceda Veterinary Record 185 22 694 694 |
institution |
Open Polar |
collection |
Universidad de Las Palmas de Gran Canaria: Acceda |
op_collection_id |
ftunivlaspalmas |
language |
English |
topic |
Investigación Takotsubo Cardiomyopathy Cardiac Troponin Capture Myopathy Beluga Whales Tako-Tsubo Pathology Features Disease Marker Death |
spellingShingle |
Investigación Takotsubo Cardiomyopathy Cardiac Troponin Capture Myopathy Beluga Whales Tako-Tsubo Pathology Features Disease Marker Death Câmara, Nakita Sierra, Eva Fernández-Maldonado, Carolina Espinosa de los Monteros, A. Arbelo, Manuel Fernández, Antonio Herráez, Pedro Stress cardiomyopathy in stranded cetaceans: a histological, histochemical and immunohistochemical study |
topic_facet |
Investigación Takotsubo Cardiomyopathy Cardiac Troponin Capture Myopathy Beluga Whales Tako-Tsubo Pathology Features Disease Marker Death |
description |
BACKGROUND: Free-living cetaceans are exposed to a wide variety of stressful situations, including live stranding and interaction with human beings (capture myopathy), vessel strikes, and fishing activities (bycatch), which affect their wellbeing and potentially lead to stress cardiomyopathy (SCMP). METHODS: Here, the authors aimed to characterise SCMP of stranded cetaceans as an injury resulting from extreme stress responses, based on pathological analyses (histological, histochemical and immunohistochemical). Specifically, the authors examined heart samples from 67 cetaceans found ashore (48 live strandings, seven dead from ship collision and 12 dead from bycatch) on the coast of Spain, more specifically in the Canary Islands from 2000 to 2016 and Andalusia from 2011 to 2014. RESULTS: The microscopic findings were characterised by vascular changes, acute or subacute cardiac degenerative necrotic lesions, interstitial myoglobin globules, and infiltration of inflammatory cells. Immunohistochemically, cardiac troponin I, cardiac troponin C and myoglobin were depleted, along with fibrinogen being expressed in the degenerated/necrotic cardiomyocytes. A perivascular pattern was also identified and described in the damaged cardiomyocytes. CONCLUSIONS: This study advances current knowledge about the pathologies of cetaceans and their implications on conserving this group of animals by reducing mortality and enhancing their treatment and subsequent rehabilitation to the marine environment. 694 694 11 |
author2 |
57191486481 15742962600 55496133700 36928058400 6603561403 57212084410 57194503614 12624727 30396242 5009228 700159 667707 32111845 30335206 WOS:Camara, N WOS:Sierra, E WOS:Fernandez-Maldonado, C WOS:de los Monteros, AE WOS:Arbelo, M WOS:Fernandez, A WOS:Herraez, P |
format |
Article in Journal/Newspaper |
author |
Câmara, Nakita Sierra, Eva Fernández-Maldonado, Carolina Espinosa de los Monteros, A. Arbelo, Manuel Fernández, Antonio Herráez, Pedro |
author_facet |
Câmara, Nakita Sierra, Eva Fernández-Maldonado, Carolina Espinosa de los Monteros, A. Arbelo, Manuel Fernández, Antonio Herráez, Pedro |
author_sort |
Câmara, Nakita |
title |
Stress cardiomyopathy in stranded cetaceans: a histological, histochemical and immunohistochemical study |
title_short |
Stress cardiomyopathy in stranded cetaceans: a histological, histochemical and immunohistochemical study |
title_full |
Stress cardiomyopathy in stranded cetaceans: a histological, histochemical and immunohistochemical study |
title_fullStr |
Stress cardiomyopathy in stranded cetaceans: a histological, histochemical and immunohistochemical study |
title_full_unstemmed |
Stress cardiomyopathy in stranded cetaceans: a histological, histochemical and immunohistochemical study |
title_sort |
stress cardiomyopathy in stranded cetaceans: a histological, histochemical and immunohistochemical study |
publishDate |
2019 |
url |
http://hdl.handle.net/10553/59990 https://doi.org/10.1136/vr.105562 |
genre |
Beluga Beluga* |
genre_facet |
Beluga Beluga* |
op_source |
The Veterinary record [ISSN 0042-4900], v. 185 (22), p. 694 |
op_relation |
Veterinary Record 185 0042-4900 Scopus http://hdl.handle.net/10553/59990 doi:10.1136/vr.105562 85076325356 000503797400023 2042-7670 22 |
op_doi |
https://doi.org/10.1136/vr.105562 |
container_title |
Veterinary Record |
container_volume |
185 |
container_issue |
22 |
container_start_page |
694 |
op_container_end_page |
694 |
_version_ |
1766374763494637568 |