Long-chain PUFA profiles in parental diets induce long-term effects on growth, fatty acid profiles, expression of fatty acid desaturase 2 and selected immune system-related genes in the offspring of gilthead seabream
The present study investigated the effects of nutritional programming through parental feeding on offspring performance and expression of selected genes related to stress resistance in a marine teleost. Gilthead seabream broodstock were fed diets containing various fish oil (FO)/vegetable oil ratios...
Published in: | British Journal of Nutrition |
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Format: | Article in Journal/Newspaper |
Language: | English |
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2019
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Online Access: | http://hdl.handle.net/10553/58369 https://doi.org/10.1017/S0007114519000977 |
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ftunivlaspalmas:oai:accedacris.ulpgc.es:10553/58369 2023-05-15T18:09:59+02:00 Long-chain PUFA profiles in parental diets induce long-term effects on growth, fatty acid profiles, expression of fatty acid desaturase 2 and selected immune system-related genes in the offspring of gilthead seabream Turkmen, Serhat Hernández Cruz, Carmen María Zamorano, Maria J. Fernandez-Palacios, Hipolito Montero, Daniel Afonso, Juan M. Izquierdo, Marisol 36150331400 55935009000 6701451831 6603285180 35605929400 57201126472 7103111891 31655267 1081294 21764463 1055780 233847 1136306 31444473 WOS:Turkmen, S WOS:Hernandez-Cruz, CM WOS:Zamorano, MJ WOS:Fernandez-Palacios, H WOS:Montero, D WOS:Afonso, JM WOS:Izquierdo, M BU-BAS 2019 http://hdl.handle.net/10553/58369 https://doi.org/10.1017/S0007114519000977 eng eng Advanced Research Initiatives For Nutrition & Aquaculture British Journal of Nutrition 122 0007-1145 WoS http://hdl.handle.net/10553/58369 doi:10.1017/S0007114519000977 85068515269 000480528200003 1475-2662 1 Sí British Journal of Nutrition [ISSN 0007-1145], v. 122 (1), p. 25-38 (julio 2019) 310502 Piscicultura Salmon Salmo-Salar Sparus Aurata Marine Teleost Fresh-Water Lipid-Metabolism Fish N-3 Performance Cloning Biosynthesis info:eu-repo/semantics/Article Article 2019 ftunivlaspalmas https://doi.org/10.1017/S0007114519000977 2021-05-04T23:10:20Z The present study investigated the effects of nutritional programming through parental feeding on offspring performance and expression of selected genes related to stress resistance in a marine teleost. Gilthead seabream broodstock were fed diets containing various fish oil (FO)/vegetable oil ratios to determine their effects on offspring performance along embryogenesis, larval development and juvenile on-growing periods. Increased substitution of dietary FO by linseed oil (LO) up to 80 % LO significantly reduced the total number of eggs produced by kg per female per spawn. Moreover, at 30 d after hatching, parental feeding with increasing LO up to 80 % led to up-regulation of the fatty acyl desaturase 2 gene (fads2) that was correlated with the increase in conversion rates of related PUFA. Besides, cyclo-oxygenase 2 (cox2) and TNF-alpha (tnf-alpha) gene expression was also up-regulated by the increase in LO in broodstock diets up to 60 or 80 %, respectively. When 4-month-old offspring were challenged with diets having different levels of FO, the lowest growth was found in juveniles from broodstock fed 100 % FO. An increase in LO levels in the broodstock diet up to 60LO raised LC-PUFA levels in the juveniles, regardless of the juvenile's diet. The results showed that it is possible to nutritionally programme gilthead seabream offspring through the modification of the fatty acid profiles of parental diets to improve the growth performance of juveniles fed low FO diets, inducing long-term changes in PUFA metabolism with up-regulation of fads2 expression. The present study provided the first pieces of evidence of the up-regulation of immune system-related genes in the offspring of parents fed increased FO replacement by LO. 38 25 14 Article in Journal/Newspaper Salmo salar Universidad de Las Palmas de Gran Canaria: Acceda British Journal of Nutrition 122 1 25 38 |
institution |
Open Polar |
collection |
Universidad de Las Palmas de Gran Canaria: Acceda |
op_collection_id |
ftunivlaspalmas |
language |
English |
topic |
310502 Piscicultura Salmon Salmo-Salar Sparus Aurata Marine Teleost Fresh-Water Lipid-Metabolism Fish N-3 Performance Cloning Biosynthesis |
spellingShingle |
310502 Piscicultura Salmon Salmo-Salar Sparus Aurata Marine Teleost Fresh-Water Lipid-Metabolism Fish N-3 Performance Cloning Biosynthesis Turkmen, Serhat Hernández Cruz, Carmen María Zamorano, Maria J. Fernandez-Palacios, Hipolito Montero, Daniel Afonso, Juan M. Izquierdo, Marisol Long-chain PUFA profiles in parental diets induce long-term effects on growth, fatty acid profiles, expression of fatty acid desaturase 2 and selected immune system-related genes in the offspring of gilthead seabream |
topic_facet |
310502 Piscicultura Salmon Salmo-Salar Sparus Aurata Marine Teleost Fresh-Water Lipid-Metabolism Fish N-3 Performance Cloning Biosynthesis |
description |
The present study investigated the effects of nutritional programming through parental feeding on offspring performance and expression of selected genes related to stress resistance in a marine teleost. Gilthead seabream broodstock were fed diets containing various fish oil (FO)/vegetable oil ratios to determine their effects on offspring performance along embryogenesis, larval development and juvenile on-growing periods. Increased substitution of dietary FO by linseed oil (LO) up to 80 % LO significantly reduced the total number of eggs produced by kg per female per spawn. Moreover, at 30 d after hatching, parental feeding with increasing LO up to 80 % led to up-regulation of the fatty acyl desaturase 2 gene (fads2) that was correlated with the increase in conversion rates of related PUFA. Besides, cyclo-oxygenase 2 (cox2) and TNF-alpha (tnf-alpha) gene expression was also up-regulated by the increase in LO in broodstock diets up to 60 or 80 %, respectively. When 4-month-old offspring were challenged with diets having different levels of FO, the lowest growth was found in juveniles from broodstock fed 100 % FO. An increase in LO levels in the broodstock diet up to 60LO raised LC-PUFA levels in the juveniles, regardless of the juvenile's diet. The results showed that it is possible to nutritionally programme gilthead seabream offspring through the modification of the fatty acid profiles of parental diets to improve the growth performance of juveniles fed low FO diets, inducing long-term changes in PUFA metabolism with up-regulation of fads2 expression. The present study provided the first pieces of evidence of the up-regulation of immune system-related genes in the offspring of parents fed increased FO replacement by LO. 38 25 14 |
author2 |
36150331400 55935009000 6701451831 6603285180 35605929400 57201126472 7103111891 31655267 1081294 21764463 1055780 233847 1136306 31444473 WOS:Turkmen, S WOS:Hernandez-Cruz, CM WOS:Zamorano, MJ WOS:Fernandez-Palacios, H WOS:Montero, D WOS:Afonso, JM WOS:Izquierdo, M BU-BAS |
format |
Article in Journal/Newspaper |
author |
Turkmen, Serhat Hernández Cruz, Carmen María Zamorano, Maria J. Fernandez-Palacios, Hipolito Montero, Daniel Afonso, Juan M. Izquierdo, Marisol |
author_facet |
Turkmen, Serhat Hernández Cruz, Carmen María Zamorano, Maria J. Fernandez-Palacios, Hipolito Montero, Daniel Afonso, Juan M. Izquierdo, Marisol |
author_sort |
Turkmen, Serhat |
title |
Long-chain PUFA profiles in parental diets induce long-term effects on growth, fatty acid profiles, expression of fatty acid desaturase 2 and selected immune system-related genes in the offspring of gilthead seabream |
title_short |
Long-chain PUFA profiles in parental diets induce long-term effects on growth, fatty acid profiles, expression of fatty acid desaturase 2 and selected immune system-related genes in the offspring of gilthead seabream |
title_full |
Long-chain PUFA profiles in parental diets induce long-term effects on growth, fatty acid profiles, expression of fatty acid desaturase 2 and selected immune system-related genes in the offspring of gilthead seabream |
title_fullStr |
Long-chain PUFA profiles in parental diets induce long-term effects on growth, fatty acid profiles, expression of fatty acid desaturase 2 and selected immune system-related genes in the offspring of gilthead seabream |
title_full_unstemmed |
Long-chain PUFA profiles in parental diets induce long-term effects on growth, fatty acid profiles, expression of fatty acid desaturase 2 and selected immune system-related genes in the offspring of gilthead seabream |
title_sort |
long-chain pufa profiles in parental diets induce long-term effects on growth, fatty acid profiles, expression of fatty acid desaturase 2 and selected immune system-related genes in the offspring of gilthead seabream |
publishDate |
2019 |
url |
http://hdl.handle.net/10553/58369 https://doi.org/10.1017/S0007114519000977 |
genre |
Salmo salar |
genre_facet |
Salmo salar |
op_source |
British Journal of Nutrition [ISSN 0007-1145], v. 122 (1), p. 25-38 (julio 2019) |
op_relation |
Advanced Research Initiatives For Nutrition & Aquaculture British Journal of Nutrition 122 0007-1145 WoS http://hdl.handle.net/10553/58369 doi:10.1017/S0007114519000977 85068515269 000480528200003 1475-2662 1 Sí |
op_doi |
https://doi.org/10.1017/S0007114519000977 |
container_title |
British Journal of Nutrition |
container_volume |
122 |
container_issue |
1 |
container_start_page |
25 |
op_container_end_page |
38 |
_version_ |
1766182695700791296 |