Retrospective study of etiologic agents associated with nonsuppurative meningoencephalitis in stranded cetaceans in the Canary Islands

• Published in: Journal of Clinical Microbiology
• Main Authors: Sierra Pulpillo, Eva María, Saliki, J.T., Blas Machado, U, Arbelo Hernández, Manuel Antonio, Succa, Daniele, Fernández Rodríguez, Antonio Jesús
• Other Authors: Arbelo, Manuel, Sierra, Eva, Fernandez, Antonio, 15742962600, 57200847111, 35517361900, 6602953170, 6603561403, 56006896100, 56673009900, 454532, 413865, 342876, 727589, 667707, 3595139, 176520, WOS:Sierra, E, WOS:Sanchez, S, WOS:Saliki, JT, WOS:Blas-Machado, U, WOS:Arbelo, M, WOS:Zucca, D, WOS:Fernandez, A
• Format: Article in Journal/Newspaper
• Language: English
• Published: 2017
• Subjects: 240119 Zoología marina; 310907 Patología; 3105 Peces y fauna silvestre; Dolphins Stenella-Coeruleoalba; Bottle-Nosed-Dolphin; Morbillivirus Infection; Tursiops-Truncatus; Delphinapterus-Leucas; Toxoplasma-Gondii; Mediterranean-Sea; Distemper Virus; Pcr; Pathology; Delphinapterus leucas
• Online Access: http://hdl.handle.net/10553/21907; https://doi.org/10.1128/JCM.02906-13

Nineteen natural cases of etiologically undetermined encephalitides in free-ranging cetaceans were studied retrospectively. Histological examination of the brains revealed variable degrees of nonsuppurative encephalitis or meningoencephalitis, characterized predominantly by perivascular lymphohistiocytic infiltrates. A PCR assay was used on brain and other available tissues to detect the presence of morbillivirus, herpesvirus, West Nile virus, Toxoplasma gondii, and Brucella spp. In addition, immunohistochemical (IHC) staining was performed on selected tissues to determine the presence of morbilliviral antigens. 2397 2397