VNTR DNA Variation in Siberian Indigenous Populations

• Main Authors: McComb, J., Blagitko, N., Comuzzie, Anthony G., Schanfield, M. S., Sukernik, R. I., Leonard, William R., Crawford, Michael H.
• Format: Article in Journal/Newspaper
• Language: unknown
• Published: Wayne State University Press 2015
• Subjects: Evenki
• Online Access: http://hdl.handle.net/1808/17920

This is the published version. Copyright 1995 Wayne State University Press. The VNTR loci D7S104, D11S129, D18S17, D20S15, and D21S112 in three indigenous Siberian populations were analyzed to determine the populations' genetic structure. Using the Kolmogorov- Smirnov test, we found that the Siberian indigenous populations of Surinda and Sulamai are separated at the D1 IS 129 locus (p < 0.05). However, the population of Poligus is genetically homogeneous compared with the villages of Sulamai and Surinda. Principal component plots for the sets of VNTR loci cluster the Siberian groups together, reflecting the homogeneity of these populations. An analysis of mean per locus heterozygosity versus the distance from the centroid of distribution suggests gene flow into Sulamai but little genetic exchange with Surinda and Poligus. Ultimately, the VNTR data reflect the genetic distinctiveness of the Kets and the Evenki.