Induction of metallothionein in dogwhelk nucella Lapillus during and after exposure to cadmium
Induction of metallothionein (MT) was investigated in a common biomonitor, the dogwhelk Nucella lapillus (shell length: 27.7 ± 1.4 mm; wet tissue weight: 667 ± 196 mg), during and after exposure to cadmium (Cd) under controlled laboratory conditions (10 ± 1°C and 34 ± 1‰ salinity). The dogwhelks wer...
Published in: | Ecotoxicology and Environmental Safety |
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Academic Press. The Journal's web site is located at http://www.elsevier.com/locate/ecoenv
1999
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Online Access: | https://doi.org/10.1006/eesa.1999.1769 http://hdl.handle.net/10722/178668 |
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ftunivhongkonghu:oai:hub.hku.hk:10722/178668 2023-05-15T18:49:53+02:00 Induction of metallothionein in dogwhelk nucella Lapillus during and after exposure to cadmium Furness, RW Leung, KMY 1999 https://doi.org/10.1006/eesa.1999.1769 http://hdl.handle.net/10722/178668 eng eng Academic Press. The Journal's web site is located at http://www.elsevier.com/locate/ecoenv United States Ecotoxicology and Environmental Safety http://www.scopus.com/mlt/select.url?eid=2-s2.0-0032990125&selection=ref&src=s&origin=recordpage Ecotoxicology And Environmental Safety, 1999, v. 43 n. 2, p. 156-164 doi:10.1006/eesa.1999.1769 164 WOS:000080633100006 0147-6513 2 10375418 eid_2-s2.0-0032990125 156 http://hdl.handle.net/10722/178668 43 Animals Cadmium - Toxicity Copper - Metabolism Iron - Metabolism Lethal Dose 50 Metallothionein - Biosynthesis Snails - Drug Effects - Metabolism Tissue Distribution Zinc - Metabolism Article 1999 ftunivhongkonghu https://doi.org/10.1006/eesa.1999.1769 2023-01-14T15:54:28Z Induction of metallothionein (MT) was investigated in a common biomonitor, the dogwhelk Nucella lapillus (shell length: 27.7 ± 1.4 mm; wet tissue weight: 667 ± 196 mg), during and after exposure to cadmium (Cd) under controlled laboratory conditions (10 ± 1°C and 34 ± 1‰ salinity). The dogwhelks were exposed to 500 μg Cd l-1 (2.2% of 96 h LC50) for 60 days and then placed into clean seawater for 110 days. MT concentration in whole animal increased during the exposure period, peaked at Day 70, and then declined gradually. Half-life of MT was ca. 40 days. MT concentration increased very significantly with increasing Cd concentration (r = 0.74, n = 24, P< 0.001). Nevertheless, Cd concentration increased throughout the period of exposure and while in clean seawater, leveling off only after Day 120, indicating that Cd concentration could not be regulated by N. lapillus. Throughout the study, MT and Cd concentrations in gills, Leiblein gland, kidney, digestive gland, and gonad tissues increased gradually. Highest concentrations of MT and Cd were found in the Leiblein gland. Measurement of MT induction in the Leiblein gland of N. lapillus may therefore prove useful as a sublethal biological response to Cd contamination. link_to_subscribed_fulltext Article in Journal/Newspaper Dogwhelk Nucella lapillus University of Hong Kong: HKU Scholars Hub Ecotoxicology and Environmental Safety 43 2 156 164 |
institution |
Open Polar |
collection |
University of Hong Kong: HKU Scholars Hub |
op_collection_id |
ftunivhongkonghu |
language |
English |
topic |
Animals Cadmium - Toxicity Copper - Metabolism Iron - Metabolism Lethal Dose 50 Metallothionein - Biosynthesis Snails - Drug Effects - Metabolism Tissue Distribution Zinc - Metabolism |
spellingShingle |
Animals Cadmium - Toxicity Copper - Metabolism Iron - Metabolism Lethal Dose 50 Metallothionein - Biosynthesis Snails - Drug Effects - Metabolism Tissue Distribution Zinc - Metabolism Furness, RW Leung, KMY Induction of metallothionein in dogwhelk nucella Lapillus during and after exposure to cadmium |
topic_facet |
Animals Cadmium - Toxicity Copper - Metabolism Iron - Metabolism Lethal Dose 50 Metallothionein - Biosynthesis Snails - Drug Effects - Metabolism Tissue Distribution Zinc - Metabolism |
description |
Induction of metallothionein (MT) was investigated in a common biomonitor, the dogwhelk Nucella lapillus (shell length: 27.7 ± 1.4 mm; wet tissue weight: 667 ± 196 mg), during and after exposure to cadmium (Cd) under controlled laboratory conditions (10 ± 1°C and 34 ± 1‰ salinity). The dogwhelks were exposed to 500 μg Cd l-1 (2.2% of 96 h LC50) for 60 days and then placed into clean seawater for 110 days. MT concentration in whole animal increased during the exposure period, peaked at Day 70, and then declined gradually. Half-life of MT was ca. 40 days. MT concentration increased very significantly with increasing Cd concentration (r = 0.74, n = 24, P< 0.001). Nevertheless, Cd concentration increased throughout the period of exposure and while in clean seawater, leveling off only after Day 120, indicating that Cd concentration could not be regulated by N. lapillus. Throughout the study, MT and Cd concentrations in gills, Leiblein gland, kidney, digestive gland, and gonad tissues increased gradually. Highest concentrations of MT and Cd were found in the Leiblein gland. Measurement of MT induction in the Leiblein gland of N. lapillus may therefore prove useful as a sublethal biological response to Cd contamination. link_to_subscribed_fulltext |
format |
Article in Journal/Newspaper |
author |
Furness, RW Leung, KMY |
author_facet |
Furness, RW Leung, KMY |
author_sort |
Furness, RW |
title |
Induction of metallothionein in dogwhelk nucella Lapillus during and after exposure to cadmium |
title_short |
Induction of metallothionein in dogwhelk nucella Lapillus during and after exposure to cadmium |
title_full |
Induction of metallothionein in dogwhelk nucella Lapillus during and after exposure to cadmium |
title_fullStr |
Induction of metallothionein in dogwhelk nucella Lapillus during and after exposure to cadmium |
title_full_unstemmed |
Induction of metallothionein in dogwhelk nucella Lapillus during and after exposure to cadmium |
title_sort |
induction of metallothionein in dogwhelk nucella lapillus during and after exposure to cadmium |
publisher |
Academic Press. The Journal's web site is located at http://www.elsevier.com/locate/ecoenv |
publishDate |
1999 |
url |
https://doi.org/10.1006/eesa.1999.1769 http://hdl.handle.net/10722/178668 |
genre |
Dogwhelk Nucella lapillus |
genre_facet |
Dogwhelk Nucella lapillus |
op_relation |
Ecotoxicology and Environmental Safety http://www.scopus.com/mlt/select.url?eid=2-s2.0-0032990125&selection=ref&src=s&origin=recordpage Ecotoxicology And Environmental Safety, 1999, v. 43 n. 2, p. 156-164 doi:10.1006/eesa.1999.1769 164 WOS:000080633100006 0147-6513 2 10375418 eid_2-s2.0-0032990125 156 http://hdl.handle.net/10722/178668 43 |
op_doi |
https://doi.org/10.1006/eesa.1999.1769 |
container_title |
Ecotoxicology and Environmental Safety |
container_volume |
43 |
container_issue |
2 |
container_start_page |
156 |
op_container_end_page |
164 |
_version_ |
1766243499024318464 |