Occupational risk variation of nasopharyngeal cancer in the Nordic countries
Abstract Background The aim of this study was to estimate occupational risk variation in the incidence of nasopharyngeal cancer (NPC) in a large population-based cohort of the Nordic Occupational Cancer (NOCCA) study. Methods This study is based on a cohort of almost 15 million persons from Denmark,...
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ftunivhelsihelda:oai:helda.helsinki.fi:10138/579640 2024-09-15T18:14:11+00:00 Occupational risk variation of nasopharyngeal cancer in the Nordic countries Carpén, Timo Gille, Evelina Hammarstedt-Nordenvall, Lalle Hansen, Johnni Heikkinen, Sanna Lynge, Elsebeth Selander, Jenny Mehlum, Ingrid S. Torfadottir, Jóhanna E. Mäkitie, Antti Pukkala, Eero 2024-07-30T14:44:11Z application/pdf http://hdl.handle.net/10138/579640 https://doi.org/10.1186/s12885-022-10209-y en eng BMC Cancer. 2022 Nov 04;22(1):1130 https://doi.org/10.1186/s12885-022-10209-y http://hdl.handle.net/10138/579640 The Author(s) Journal Article 2024 ftunivhelsihelda https://doi.org/10.1186/s12885-022-10209-y 2024-07-31T23:42:50Z Abstract Background The aim of this study was to estimate occupational risk variation in the incidence of nasopharyngeal cancer (NPC) in a large population-based cohort of the Nordic Occupational Cancer (NOCCA) study. Methods This study is based on a cohort of almost 15 million persons from Denmark, Finland, Iceland, Norway and Sweden, with 2898 nasopharyngeal cancer cases diagnosed in 1961–2005. The data on occupations were gathered from population censuses and cancer data from the national cancer registries. Standardized incidence ratios (SIR) with 95% confidence intervals (CI) were estimated using the national NPC incidence rates as the reference. Results There were 1980 male and 918 female NPC patients. The highest SIRs of NPC were observed among male waiters (SIR 3.69, 95% CI 1.91–6.45) and cooks and stewards (SIR 2.24, 95% CI 1.16–3.91). Among women, launderers had the highest SIR of NPC (2.04, 95% CI 1.02–3.65). Significantly decreased SIRs were found among male farmers (SIR 0.79, 95% CI 0.68–0.92) and male textile workers (SIR 0.49, 95% CI 0.22–0.93). Conclusions This study suggests that NPC may be associated with several work-related exposure agents such as smoking, kitchen air pollution and solvents. In future, occupational exposure-risk relations should be studied to understand more about causality and to assess effective prevention strategies. Article in Journal/Newspaper Iceland HELDA – University of Helsinki Open Repository BMC Cancer 22 1 |
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Open Polar |
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HELDA – University of Helsinki Open Repository |
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ftunivhelsihelda |
language |
English |
description |
Abstract Background The aim of this study was to estimate occupational risk variation in the incidence of nasopharyngeal cancer (NPC) in a large population-based cohort of the Nordic Occupational Cancer (NOCCA) study. Methods This study is based on a cohort of almost 15 million persons from Denmark, Finland, Iceland, Norway and Sweden, with 2898 nasopharyngeal cancer cases diagnosed in 1961–2005. The data on occupations were gathered from population censuses and cancer data from the national cancer registries. Standardized incidence ratios (SIR) with 95% confidence intervals (CI) were estimated using the national NPC incidence rates as the reference. Results There were 1980 male and 918 female NPC patients. The highest SIRs of NPC were observed among male waiters (SIR 3.69, 95% CI 1.91–6.45) and cooks and stewards (SIR 2.24, 95% CI 1.16–3.91). Among women, launderers had the highest SIR of NPC (2.04, 95% CI 1.02–3.65). Significantly decreased SIRs were found among male farmers (SIR 0.79, 95% CI 0.68–0.92) and male textile workers (SIR 0.49, 95% CI 0.22–0.93). Conclusions This study suggests that NPC may be associated with several work-related exposure agents such as smoking, kitchen air pollution and solvents. In future, occupational exposure-risk relations should be studied to understand more about causality and to assess effective prevention strategies. |
format |
Article in Journal/Newspaper |
author |
Carpén, Timo Gille, Evelina Hammarstedt-Nordenvall, Lalle Hansen, Johnni Heikkinen, Sanna Lynge, Elsebeth Selander, Jenny Mehlum, Ingrid S. Torfadottir, Jóhanna E. Mäkitie, Antti Pukkala, Eero |
spellingShingle |
Carpén, Timo Gille, Evelina Hammarstedt-Nordenvall, Lalle Hansen, Johnni Heikkinen, Sanna Lynge, Elsebeth Selander, Jenny Mehlum, Ingrid S. Torfadottir, Jóhanna E. Mäkitie, Antti Pukkala, Eero Occupational risk variation of nasopharyngeal cancer in the Nordic countries |
author_facet |
Carpén, Timo Gille, Evelina Hammarstedt-Nordenvall, Lalle Hansen, Johnni Heikkinen, Sanna Lynge, Elsebeth Selander, Jenny Mehlum, Ingrid S. Torfadottir, Jóhanna E. Mäkitie, Antti Pukkala, Eero |
author_sort |
Carpén, Timo |
title |
Occupational risk variation of nasopharyngeal cancer in the Nordic countries |
title_short |
Occupational risk variation of nasopharyngeal cancer in the Nordic countries |
title_full |
Occupational risk variation of nasopharyngeal cancer in the Nordic countries |
title_fullStr |
Occupational risk variation of nasopharyngeal cancer in the Nordic countries |
title_full_unstemmed |
Occupational risk variation of nasopharyngeal cancer in the Nordic countries |
title_sort |
occupational risk variation of nasopharyngeal cancer in the nordic countries |
publishDate |
2024 |
url |
http://hdl.handle.net/10138/579640 https://doi.org/10.1186/s12885-022-10209-y |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
BMC Cancer. 2022 Nov 04;22(1):1130 https://doi.org/10.1186/s12885-022-10209-y http://hdl.handle.net/10138/579640 |
op_rights |
The Author(s) |
op_doi |
https://doi.org/10.1186/s12885-022-10209-y |
container_title |
BMC Cancer |
container_volume |
22 |
container_issue |
1 |
_version_ |
1810451955585122304 |