Self-Applied Electrode Set Provides a Clinically Feasible Solution Enabling EEG Recording in Home Sleep Apnea Testing
Home sleep apnea testing (HSAT) without electroencephalography (EEG) recording is increasingly used as an alternative to in-laboratory polysomnography for the diagnosis of obstructive sleep apnea (OSA). However, without EEG, electrooculography (EOG), and chin electromyography (EMG) recordings, the O...
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IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
2022
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Online Access: | http://hdl.handle.net/10138/346377 |
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ftunivhelsihelda:oai:helda.helsinki.fi:10138/346377 |
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Open Polar |
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HELDA – University of Helsinki Open Repository |
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ftunivhelsihelda |
language |
English |
topic |
Bioimpedance biomedical electrodes biomedical monitoring electroencephalography obstructive sleep apnea POLYSOMNOGRAPHY VARIABILITY DEFINITION IMPEDANCE 3121 General medicine internal medicine and other clinical medicine |
spellingShingle |
Bioimpedance biomedical electrodes biomedical monitoring electroencephalography obstructive sleep apnea POLYSOMNOGRAPHY VARIABILITY DEFINITION IMPEDANCE 3121 General medicine internal medicine and other clinical medicine Kalevo, Laura Miettinen, Tomi Leino, Akseli Westeren-Punnonen, Susanna Sahlman, Johanna Mervaala, Esa Toyras, Juha Leppanen, Timo Myllymaa, Sami Myllymaa, Katja Self-Applied Electrode Set Provides a Clinically Feasible Solution Enabling EEG Recording in Home Sleep Apnea Testing |
topic_facet |
Bioimpedance biomedical electrodes biomedical monitoring electroencephalography obstructive sleep apnea POLYSOMNOGRAPHY VARIABILITY DEFINITION IMPEDANCE 3121 General medicine internal medicine and other clinical medicine |
description |
Home sleep apnea testing (HSAT) without electroencephalography (EEG) recording is increasingly used as an alternative to in-laboratory polysomnography for the diagnosis of obstructive sleep apnea (OSA). However, without EEG, electrooculography (EOG), and chin electromyography (EMG) recordings, the OSA severity may be significantly underestimated. Although several ambulatory EEG systems have been recently introduced, no patient-applied systems including EEG, EOG, and chin EMG suitable for home polysomnography are currently in clinical use. We have recently developed and pre-clinically tested a self-applied ambulatory electrode set (AES), consisting of frontal EEG, EOG, and EMG, in subjects with possible sleep bruxism. Now, in this clinical feasibility study, we investigated the signal scorability and usability of the AES as a self-administered sleep assessment approach supplementing the conventional HSAT device. We also investigated how the diagnostic parameters and OSA severity changed when utilizing the AES. Thirty-eight patients (61 % male, 25-78 years) with a clinical suspicion of OSA conducted a single-night, self-administered HSAT with a portable polysomnography device (Nox A1, Nox Medical, Reykjavik, Iceland) supplemented with AES. Only one AES recording failed. The use of AES signals in data analysis significantly affected the median apnea-hypopnea index (AHI), increasing it from 9.4 to 12.7 events/h (p < 0.001) compared to the conventional HSAT. Also, in eight patients, the OSA severity class changed to one class worse. Perceived ease of use was well in line with that previously found among healthy volunteers. These results suggest that the AES provides an easy, clinically feasible solution to record EEG as a part of conventional HSAT. Peer reviewed |
author2 |
University of Helsinki Department of Oncology HUS Comprehensive Cancer Center |
format |
Article in Journal/Newspaper |
author |
Kalevo, Laura Miettinen, Tomi Leino, Akseli Westeren-Punnonen, Susanna Sahlman, Johanna Mervaala, Esa Toyras, Juha Leppanen, Timo Myllymaa, Sami Myllymaa, Katja |
author_facet |
Kalevo, Laura Miettinen, Tomi Leino, Akseli Westeren-Punnonen, Susanna Sahlman, Johanna Mervaala, Esa Toyras, Juha Leppanen, Timo Myllymaa, Sami Myllymaa, Katja |
author_sort |
Kalevo, Laura |
title |
Self-Applied Electrode Set Provides a Clinically Feasible Solution Enabling EEG Recording in Home Sleep Apnea Testing |
title_short |
Self-Applied Electrode Set Provides a Clinically Feasible Solution Enabling EEG Recording in Home Sleep Apnea Testing |
title_full |
Self-Applied Electrode Set Provides a Clinically Feasible Solution Enabling EEG Recording in Home Sleep Apnea Testing |
title_fullStr |
Self-Applied Electrode Set Provides a Clinically Feasible Solution Enabling EEG Recording in Home Sleep Apnea Testing |
title_full_unstemmed |
Self-Applied Electrode Set Provides a Clinically Feasible Solution Enabling EEG Recording in Home Sleep Apnea Testing |
title_sort |
self-applied electrode set provides a clinically feasible solution enabling eeg recording in home sleep apnea testing |
publisher |
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC |
publishDate |
2022 |
url |
http://hdl.handle.net/10138/346377 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
10.1109/ACCESS.2022.3178189 This work was supported in part by the European Union's Horizon 2020 Research and Innovation Program under Grant Agreement 965417; in part by NordForsk (NordSleep Project 90458) via Business Finland under Grant 5133/31/2018; in part by the Academy of Finland under Grant 323536; in part by the Research Committee of the Kuopio University Hospital Catchment Area for the State Research Funding under Grant 5041764, Grant 5041767, Grant 5041768, Grant 5041770, Grant 5041776, Grant 5041782, Grant 5041794, and Grant 5041797; in part by the Finnish Cultural Foundation North Savo Regional Fund; in part by the Research Foundation of the Pulmonary Diseases; in part by the Finnish Anti-Tuberculosis Association; in part by the Tampere Tuberculosis Foundation; and in part by the Respiratory Foundation of Kuopio Region. Kalevo , L , Miettinen , T , Leino , A , Westeren-Punnonen , S , Sahlman , J , Mervaala , E , Toyras , J , Leppanen , T , Myllymaa , S & Myllymaa , K 2022 , ' Self-Applied Electrode Set Provides a Clinically Feasible Solution Enabling EEG Recording in Home Sleep Apnea Testing ' , IEEE Access , vol. 10 , pp. 60633-60642 . https://doi.org/10.1109/ACCESS.2022.3178189 8ca6fea2-e621-4e6e-8cd1-a887a4cd2c44 http://hdl.handle.net/10138/346377 000811548100001 |
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cc_by openAccess info:eu-repo/semantics/openAccess |
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IEEE Access |
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10 |
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60633 |
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60642 |
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1787425632807813120 |
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ftunivhelsihelda:oai:helda.helsinki.fi:10138/346377 2024-01-07T09:44:16+01:00 Self-Applied Electrode Set Provides a Clinically Feasible Solution Enabling EEG Recording in Home Sleep Apnea Testing Kalevo, Laura Miettinen, Tomi Leino, Akseli Westeren-Punnonen, Susanna Sahlman, Johanna Mervaala, Esa Toyras, Juha Leppanen, Timo Myllymaa, Sami Myllymaa, Katja University of Helsinki Department of Oncology HUS Comprehensive Cancer Center 2022-07-25T06:19:06Z 10 application/pdf http://hdl.handle.net/10138/346377 eng eng IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC 10.1109/ACCESS.2022.3178189 This work was supported in part by the European Union's Horizon 2020 Research and Innovation Program under Grant Agreement 965417; in part by NordForsk (NordSleep Project 90458) via Business Finland under Grant 5133/31/2018; in part by the Academy of Finland under Grant 323536; in part by the Research Committee of the Kuopio University Hospital Catchment Area for the State Research Funding under Grant 5041764, Grant 5041767, Grant 5041768, Grant 5041770, Grant 5041776, Grant 5041782, Grant 5041794, and Grant 5041797; in part by the Finnish Cultural Foundation North Savo Regional Fund; in part by the Research Foundation of the Pulmonary Diseases; in part by the Finnish Anti-Tuberculosis Association; in part by the Tampere Tuberculosis Foundation; and in part by the Respiratory Foundation of Kuopio Region. Kalevo , L , Miettinen , T , Leino , A , Westeren-Punnonen , S , Sahlman , J , Mervaala , E , Toyras , J , Leppanen , T , Myllymaa , S & Myllymaa , K 2022 , ' Self-Applied Electrode Set Provides a Clinically Feasible Solution Enabling EEG Recording in Home Sleep Apnea Testing ' , IEEE Access , vol. 10 , pp. 60633-60642 . https://doi.org/10.1109/ACCESS.2022.3178189 8ca6fea2-e621-4e6e-8cd1-a887a4cd2c44 http://hdl.handle.net/10138/346377 000811548100001 cc_by openAccess info:eu-repo/semantics/openAccess Bioimpedance biomedical electrodes biomedical monitoring electroencephalography obstructive sleep apnea POLYSOMNOGRAPHY VARIABILITY DEFINITION IMPEDANCE 3121 General medicine internal medicine and other clinical medicine Article publishedVersion 2022 ftunivhelsihelda 2023-12-14T00:03:55Z Home sleep apnea testing (HSAT) without electroencephalography (EEG) recording is increasingly used as an alternative to in-laboratory polysomnography for the diagnosis of obstructive sleep apnea (OSA). However, without EEG, electrooculography (EOG), and chin electromyography (EMG) recordings, the OSA severity may be significantly underestimated. Although several ambulatory EEG systems have been recently introduced, no patient-applied systems including EEG, EOG, and chin EMG suitable for home polysomnography are currently in clinical use. We have recently developed and pre-clinically tested a self-applied ambulatory electrode set (AES), consisting of frontal EEG, EOG, and EMG, in subjects with possible sleep bruxism. Now, in this clinical feasibility study, we investigated the signal scorability and usability of the AES as a self-administered sleep assessment approach supplementing the conventional HSAT device. We also investigated how the diagnostic parameters and OSA severity changed when utilizing the AES. Thirty-eight patients (61 % male, 25-78 years) with a clinical suspicion of OSA conducted a single-night, self-administered HSAT with a portable polysomnography device (Nox A1, Nox Medical, Reykjavik, Iceland) supplemented with AES. Only one AES recording failed. The use of AES signals in data analysis significantly affected the median apnea-hypopnea index (AHI), increasing it from 9.4 to 12.7 events/h (p < 0.001) compared to the conventional HSAT. Also, in eight patients, the OSA severity class changed to one class worse. Perceived ease of use was well in line with that previously found among healthy volunteers. These results suggest that the AES provides an easy, clinically feasible solution to record EEG as a part of conventional HSAT. Peer reviewed Article in Journal/Newspaper Iceland HELDA – University of Helsinki Open Repository IEEE Access 10 60633 60642 |