Weight-Related and Personal Risk Factors of Carpal Tunnel Syndrome in the Northern Finland Birth Cohort 1966
Background: Excess body mass is a risk factor for carpal tunnel syndrome (CTS), but the mechanisms of this are unclear. This study aimed to evaluate the association between CTS and personal risk factors of body mass index (BMI), waist circumference and waist-to-hip ratio (WHR). Methods: The study sa...
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ftunivhelsihelda:oai:helda.helsinki.fi:10138/343036 2024-01-07T09:45:27+01:00 Weight-Related and Personal Risk Factors of Carpal Tunnel Syndrome in the Northern Finland Birth Cohort 1966 Lampainen, Kaisa Shiri, Rahman Auvinen, Juha Karppinen, Jaro Ryhänen, Jorma Hulkkonen, Sina I kirurgian klinikka (Töölö) HUS Musculoskeletal and Plastic Surgery South Carelia Social and Health care District Eksote HYKS erva Department of Surgery University of Helsinki 2022-04-26T11:41:03Z 9 application/pdf http://hdl.handle.net/10138/343036 eng eng MDPI 10.3390/jcm11061510 We thank all cohort members and researchers who participated in the 31 and 47 years studies. We also wish to acknowledge the work of the NFBC project center. We thank Rehabilitation Foundation Peurunka for K.L.'s research grant and the Finnish Medical Foundation for S.H.'s research grant. Lampainen , K , Shiri , R , Auvinen , J , Karppinen , J , Ryhänen , J & Hulkkonen , S 2022 , ' Weight-Related and Personal Risk Factors of Carpal Tunnel Syndrome in the Northern Finland Birth Cohort 1966 ' , Journal of clinical medicine , vol. 11 , no. 6 , 1510 . https://doi.org/10.3390/jcm11061510 ORCID: /0000-0002-4676-2831/work/120006721 33431e9a-40c5-4765-b850-1989f157dec2 http://hdl.handle.net/10138/343036 000775110300001 cc_by openAccess info:eu-repo/semantics/openAccess carpal tunnel syndrome body mass index waist circumference waist-to-hip ratio obesity median nerve BODY-MASS PREVALENCE DISORDERS WORK 3121 General medicine internal medicine and other clinical medicine 3126 Surgery anesthesiology intensive care radiology Article publishedVersion 2022 ftunivhelsihelda 2023-12-14T00:05:01Z Background: Excess body mass is a risk factor for carpal tunnel syndrome (CTS), but the mechanisms of this are unclear. This study aimed to evaluate the association between CTS and personal risk factors of body mass index (BMI), waist circumference and waist-to-hip ratio (WHR). Methods: The study sample consisted of the Northern Finland Birth Cohort 1966 (n = 9246). At the age of 31 in 1997 and at the age of 46 in 2012, the participants underwent a clinical examination. Cohort A consisted of complete cases with a follow-up from 1997 to 2012 (n = 4701), and Cohort B was followed up from 2012 to 2018 (n = 4548). The data on diagnosed CTS were provided by the Care Register for Health Care until the end of 2018. Results: After an adjustment for confounding factors, BMI was associated with CTS among women (hazard ratio (HR) 1.47, 95% Cl 0.98-2.20 for overweight women and HR 2.22, 95% Cl 1.29-3.83 for obese women) and among both sexes combined (HR 1.35 95% Cl 0.96-1.90 for overweight and HR 1.98 95% Cl 1.22-3.22 for obese participants). Neither waist circumference nor WHR was associated with CTS. Conclusions: BMI is an independent risk factor for CTS and is more relevant for estimating the increased risk of CTS due to excess body mass than waist circumference or WHR. Peer reviewed Article in Journal/Newspaper Northern Finland HELDA – University of Helsinki Open Repository Journal of Clinical Medicine 11 6 1510 |
institution |
Open Polar |
collection |
HELDA – University of Helsinki Open Repository |
op_collection_id |
ftunivhelsihelda |
language |
English |
topic |
carpal tunnel syndrome body mass index waist circumference waist-to-hip ratio obesity median nerve BODY-MASS PREVALENCE DISORDERS WORK 3121 General medicine internal medicine and other clinical medicine 3126 Surgery anesthesiology intensive care radiology |
spellingShingle |
carpal tunnel syndrome body mass index waist circumference waist-to-hip ratio obesity median nerve BODY-MASS PREVALENCE DISORDERS WORK 3121 General medicine internal medicine and other clinical medicine 3126 Surgery anesthesiology intensive care radiology Lampainen, Kaisa Shiri, Rahman Auvinen, Juha Karppinen, Jaro Ryhänen, Jorma Hulkkonen, Sina Weight-Related and Personal Risk Factors of Carpal Tunnel Syndrome in the Northern Finland Birth Cohort 1966 |
topic_facet |
carpal tunnel syndrome body mass index waist circumference waist-to-hip ratio obesity median nerve BODY-MASS PREVALENCE DISORDERS WORK 3121 General medicine internal medicine and other clinical medicine 3126 Surgery anesthesiology intensive care radiology |
description |
Background: Excess body mass is a risk factor for carpal tunnel syndrome (CTS), but the mechanisms of this are unclear. This study aimed to evaluate the association between CTS and personal risk factors of body mass index (BMI), waist circumference and waist-to-hip ratio (WHR). Methods: The study sample consisted of the Northern Finland Birth Cohort 1966 (n = 9246). At the age of 31 in 1997 and at the age of 46 in 2012, the participants underwent a clinical examination. Cohort A consisted of complete cases with a follow-up from 1997 to 2012 (n = 4701), and Cohort B was followed up from 2012 to 2018 (n = 4548). The data on diagnosed CTS were provided by the Care Register for Health Care until the end of 2018. Results: After an adjustment for confounding factors, BMI was associated with CTS among women (hazard ratio (HR) 1.47, 95% Cl 0.98-2.20 for overweight women and HR 2.22, 95% Cl 1.29-3.83 for obese women) and among both sexes combined (HR 1.35 95% Cl 0.96-1.90 for overweight and HR 1.98 95% Cl 1.22-3.22 for obese participants). Neither waist circumference nor WHR was associated with CTS. Conclusions: BMI is an independent risk factor for CTS and is more relevant for estimating the increased risk of CTS due to excess body mass than waist circumference or WHR. Peer reviewed |
author2 |
I kirurgian klinikka (Töölö) HUS Musculoskeletal and Plastic Surgery South Carelia Social and Health care District Eksote HYKS erva Department of Surgery University of Helsinki |
format |
Article in Journal/Newspaper |
author |
Lampainen, Kaisa Shiri, Rahman Auvinen, Juha Karppinen, Jaro Ryhänen, Jorma Hulkkonen, Sina |
author_facet |
Lampainen, Kaisa Shiri, Rahman Auvinen, Juha Karppinen, Jaro Ryhänen, Jorma Hulkkonen, Sina |
author_sort |
Lampainen, Kaisa |
title |
Weight-Related and Personal Risk Factors of Carpal Tunnel Syndrome in the Northern Finland Birth Cohort 1966 |
title_short |
Weight-Related and Personal Risk Factors of Carpal Tunnel Syndrome in the Northern Finland Birth Cohort 1966 |
title_full |
Weight-Related and Personal Risk Factors of Carpal Tunnel Syndrome in the Northern Finland Birth Cohort 1966 |
title_fullStr |
Weight-Related and Personal Risk Factors of Carpal Tunnel Syndrome in the Northern Finland Birth Cohort 1966 |
title_full_unstemmed |
Weight-Related and Personal Risk Factors of Carpal Tunnel Syndrome in the Northern Finland Birth Cohort 1966 |
title_sort |
weight-related and personal risk factors of carpal tunnel syndrome in the northern finland birth cohort 1966 |
publisher |
MDPI |
publishDate |
2022 |
url |
http://hdl.handle.net/10138/343036 |
genre |
Northern Finland |
genre_facet |
Northern Finland |
op_relation |
10.3390/jcm11061510 We thank all cohort members and researchers who participated in the 31 and 47 years studies. We also wish to acknowledge the work of the NFBC project center. We thank Rehabilitation Foundation Peurunka for K.L.'s research grant and the Finnish Medical Foundation for S.H.'s research grant. Lampainen , K , Shiri , R , Auvinen , J , Karppinen , J , Ryhänen , J & Hulkkonen , S 2022 , ' Weight-Related and Personal Risk Factors of Carpal Tunnel Syndrome in the Northern Finland Birth Cohort 1966 ' , Journal of clinical medicine , vol. 11 , no. 6 , 1510 . https://doi.org/10.3390/jcm11061510 ORCID: /0000-0002-4676-2831/work/120006721 33431e9a-40c5-4765-b850-1989f157dec2 http://hdl.handle.net/10138/343036 000775110300001 |
op_rights |
cc_by openAccess info:eu-repo/semantics/openAccess |
container_title |
Journal of Clinical Medicine |
container_volume |
11 |
container_issue |
6 |
container_start_page |
1510 |
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1787426985013673984 |