Polygenic and major-locus contributions to sexual maturation timing in Atlantic salmon
Sexual maturation timing is a life-history trait central to the balance between mortality and reproduction. Maturation may be triggered when an underlying compound trait, called liability, exceeds a threshold. In many different species and especially fishes, this liability is approximated by growth...
Published in: | Molecular Ecology |
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ftunivhelsihelda:oai:helda.helsinki.fi:10138/334420 2024-01-07T09:42:14+01:00 Polygenic and major-locus contributions to sexual maturation timing in Atlantic salmon Debes, Paul Piavchenko, Nikolai Ruokolainen, Annukka Ovaskainen, Outi Moustakas-Verho, Jacqueline E. Parre, Noora Aykanat, Tutku Erkinaro, Jaakko Primmer, Craig R. Evolution, Conservation, and Genomics Organismal and Evolutionary Biology Research Programme Zoology Biosciences Genetics Institute of Biotechnology Helsinki Institute of Sustainability Science (HELSUS) 2021-09-16T11:59:03Z 15 application/pdf http://hdl.handle.net/10138/334420 eng eng Wiley 10.1111/mec.16062 Academy of Finland, Grant/Award Number: 284941, 286334, 314254 and 314255; H2020 European Research Council, Grant/Award Number: 742312 Debes , P , Piavchenko , N , Ruokolainen , A , Ovaskainen , O , Moustakas-Verho , J E , Parre , N , Aykanat , T , Erkinaro , J & Primmer , C R 2021 , ' Polygenic and major-locus contributions to sexual maturation timing in Atlantic salmon ' , Molecular Ecology , vol. 30 , no. 18 , pp. 4505-4519 . https://doi.org/10.1111/mec.16062 ORCID: /0000-0001-9702-0945/work/100082278 ORCID: /0000-0002-3687-8435/work/100085111 951d55bc-eb51-45f3-a8ce-1de140de5d5b http://hdl.handle.net/10138/334420 000675260200001 cc_by openAccess info:eu-repo/semantics/openAccess feed restriction genetic correlation large effect locus life-history trait sexual maturation LIFE-HISTORY VARIATION DEPENDENT DOMINANCE GENERAL-METHODS REACTION NORMS SALAR GROWTH SELECTION MATURITY EVOLUTION MODELS 1181 Ecology evolutionary biology 1182 Biochemistry cell and molecular biology Article publishedVersion 2021 ftunivhelsihelda 2023-12-14T00:02:09Z Sexual maturation timing is a life-history trait central to the balance between mortality and reproduction. Maturation may be triggered when an underlying compound trait, called liability, exceeds a threshold. In many different species and especially fishes, this liability is approximated by growth and body condition. However, environmental vs. genetic contributions either directly or via growth and body condition to maturation timing remain unclear. Uncertainty exists also because the maturation process can reverse this causality and itself affect growth and body condition. In addition, disentangling the contributions of polygenic and major loci can be important. In many fishes, males mature before females, enabling the study of associations between male maturation and maturation-unbiased female liability traits. Using 40 Atlantic salmon families, longitudinal common-garden experimentation, and quantitative genetic analyses, we disentangled environmental from polygenic and major locus (vgll3) effects on male maturation, and sex-specific growth and condition. We detected polygenic heritabilities for maturation, growth, and body condition, and vgll3 effects on maturation and body condition but not on growth. Longitudinal patterns for sex-specific phenotypic liability, and for genetic variances and correlations between sexes suggested that early growth and condition indeed positively affected maturation initiation. However, towards spawning time, causality appeared reversed for males whereby maturation affected growth negatively and condition positively via both the environmental and genetic effects. Altogether, the results indicate that growth and condition are useful traits to study liability for maturation initiation, but only until maturation alters their expression, and that vgll3 contributes to maturation initiation via condition. Peer reviewed Article in Journal/Newspaper Atlantic salmon HELDA – University of Helsinki Open Repository Molecular Ecology 30 18 4505 4519 |
institution |
Open Polar |
collection |
HELDA – University of Helsinki Open Repository |
op_collection_id |
ftunivhelsihelda |
language |
English |
topic |
feed restriction genetic correlation large effect locus life-history trait sexual maturation LIFE-HISTORY VARIATION DEPENDENT DOMINANCE GENERAL-METHODS REACTION NORMS SALAR GROWTH SELECTION MATURITY EVOLUTION MODELS 1181 Ecology evolutionary biology 1182 Biochemistry cell and molecular biology |
spellingShingle |
feed restriction genetic correlation large effect locus life-history trait sexual maturation LIFE-HISTORY VARIATION DEPENDENT DOMINANCE GENERAL-METHODS REACTION NORMS SALAR GROWTH SELECTION MATURITY EVOLUTION MODELS 1181 Ecology evolutionary biology 1182 Biochemistry cell and molecular biology Debes, Paul Piavchenko, Nikolai Ruokolainen, Annukka Ovaskainen, Outi Moustakas-Verho, Jacqueline E. Parre, Noora Aykanat, Tutku Erkinaro, Jaakko Primmer, Craig R. Polygenic and major-locus contributions to sexual maturation timing in Atlantic salmon |
topic_facet |
feed restriction genetic correlation large effect locus life-history trait sexual maturation LIFE-HISTORY VARIATION DEPENDENT DOMINANCE GENERAL-METHODS REACTION NORMS SALAR GROWTH SELECTION MATURITY EVOLUTION MODELS 1181 Ecology evolutionary biology 1182 Biochemistry cell and molecular biology |
description |
Sexual maturation timing is a life-history trait central to the balance between mortality and reproduction. Maturation may be triggered when an underlying compound trait, called liability, exceeds a threshold. In many different species and especially fishes, this liability is approximated by growth and body condition. However, environmental vs. genetic contributions either directly or via growth and body condition to maturation timing remain unclear. Uncertainty exists also because the maturation process can reverse this causality and itself affect growth and body condition. In addition, disentangling the contributions of polygenic and major loci can be important. In many fishes, males mature before females, enabling the study of associations between male maturation and maturation-unbiased female liability traits. Using 40 Atlantic salmon families, longitudinal common-garden experimentation, and quantitative genetic analyses, we disentangled environmental from polygenic and major locus (vgll3) effects on male maturation, and sex-specific growth and condition. We detected polygenic heritabilities for maturation, growth, and body condition, and vgll3 effects on maturation and body condition but not on growth. Longitudinal patterns for sex-specific phenotypic liability, and for genetic variances and correlations between sexes suggested that early growth and condition indeed positively affected maturation initiation. However, towards spawning time, causality appeared reversed for males whereby maturation affected growth negatively and condition positively via both the environmental and genetic effects. Altogether, the results indicate that growth and condition are useful traits to study liability for maturation initiation, but only until maturation alters their expression, and that vgll3 contributes to maturation initiation via condition. Peer reviewed |
author2 |
Evolution, Conservation, and Genomics Organismal and Evolutionary Biology Research Programme Zoology Biosciences Genetics Institute of Biotechnology Helsinki Institute of Sustainability Science (HELSUS) |
format |
Article in Journal/Newspaper |
author |
Debes, Paul Piavchenko, Nikolai Ruokolainen, Annukka Ovaskainen, Outi Moustakas-Verho, Jacqueline E. Parre, Noora Aykanat, Tutku Erkinaro, Jaakko Primmer, Craig R. |
author_facet |
Debes, Paul Piavchenko, Nikolai Ruokolainen, Annukka Ovaskainen, Outi Moustakas-Verho, Jacqueline E. Parre, Noora Aykanat, Tutku Erkinaro, Jaakko Primmer, Craig R. |
author_sort |
Debes, Paul |
title |
Polygenic and major-locus contributions to sexual maturation timing in Atlantic salmon |
title_short |
Polygenic and major-locus contributions to sexual maturation timing in Atlantic salmon |
title_full |
Polygenic and major-locus contributions to sexual maturation timing in Atlantic salmon |
title_fullStr |
Polygenic and major-locus contributions to sexual maturation timing in Atlantic salmon |
title_full_unstemmed |
Polygenic and major-locus contributions to sexual maturation timing in Atlantic salmon |
title_sort |
polygenic and major-locus contributions to sexual maturation timing in atlantic salmon |
publisher |
Wiley |
publishDate |
2021 |
url |
http://hdl.handle.net/10138/334420 |
genre |
Atlantic salmon |
genre_facet |
Atlantic salmon |
op_relation |
10.1111/mec.16062 Academy of Finland, Grant/Award Number: 284941, 286334, 314254 and 314255; H2020 European Research Council, Grant/Award Number: 742312 Debes , P , Piavchenko , N , Ruokolainen , A , Ovaskainen , O , Moustakas-Verho , J E , Parre , N , Aykanat , T , Erkinaro , J & Primmer , C R 2021 , ' Polygenic and major-locus contributions to sexual maturation timing in Atlantic salmon ' , Molecular Ecology , vol. 30 , no. 18 , pp. 4505-4519 . https://doi.org/10.1111/mec.16062 ORCID: /0000-0001-9702-0945/work/100082278 ORCID: /0000-0002-3687-8435/work/100085111 951d55bc-eb51-45f3-a8ce-1de140de5d5b http://hdl.handle.net/10138/334420 000675260200001 |
op_rights |
cc_by openAccess info:eu-repo/semantics/openAccess |
container_title |
Molecular Ecology |
container_volume |
30 |
container_issue |
18 |
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4505 |
op_container_end_page |
4519 |
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1787423172262363136 |