Nordic consensus statement on the systematic assessment and management of possible severe asthma in adults

• Published in: European Clinical Respiratory Journal
• Main Authors: Porsbjerg, Celeste, Ulrik, Charlotte, Skjold, Tina, Backer, Vibeke, Laerum, Birger, Lehman, Sverre, Janson, Crister, Sandstrom, Thomas, Bjermer, Leif, Dahlen, Barbro, Lundback, Bo, Ludviksdottir, Dora, Bjornsdottir, Unnur, Altraja, Alan, Lehtimaki, Lauri, Kauppi, Paula, Karjalainen, Jussi, Kankaanranta, Hannu
• Other Authors: Faculty of Medicine, HUS Inflammation Center
• Format: Review
• Language: English
• Published: Co-Action Publishing 2019
• Subjects: Asthma; severe; prevalence; diagnosis; co-morbidities; management; guideline; SEVERE ALLERGIC-ASTHMA; PLACEBO-CONTROLLED TRIAL; QUALITY-OF-LIFE; GASTROESOPHAGEAL-REFLUX DISEASE; RANDOMIZED CONTROLLED-TRIAL; OBSTRUCTIVE SLEEP-APNEA; VOCAL CORD DYSFUNCTION; CLINICAL-PRACTICE GUIDELINE; SEVERE UNCONTROLLED ASTHMA; TO-TREAT ASTHMA; 3121 General medicine; internal medicine and other clinical medicine; Norway; Iceland
• Online Access: http://hdl.handle.net/10138/299404

Although a minority of asthma patients suffer from severe asthma, they represent a major clinical challenge in terms of poor symptom control despite high-dose treatment, risk of exacerbations, and side effects. Novel biological treatments may benefit patients with severe asthma, but are expensive, and are only effective in appropriately targeted patients. In some patients, symptoms are driven by other factors than asthma, and all patients with suspected severe asthma ('difficult asthma') should undergo systematic assessment, in order to differentiate between true severe asthma, and 'difficult-to-treat' patients, in whom poor control is related to factors such as poor adherence or co-morbidities. The Nordic Consensus Statement on severe asthma was developed by the Nordic Severe Asthma Network, consisting of members from Norway, Sweden, Finland, Denmark, Iceland and Estonia, including representatives from the respective national respiratory scientific societies with the aim to provide an overview and recommendations regarding the diagnosis, systematic assessment and management of severe asthma. Furthermore, the Consensus Statement proposes recommendations for the organization of severe asthma management in primary, secondary, and tertiary care. Peer reviewed