Infectious keratoconjunctivitis in semi-domesticated Eurasian tundra reindeer (Rangifer tarandus tarandus) : microbiological study of clinically affected and unaffected animals with special reference to cervid herpesvirus 2
Background: Infectious keratoconjunctivitis (IKC) is one of the most common ocular diseases in ruminants worldwide. In addition to keratitis and conjunctivitis, animals with IKC can develop uveitis, corneal ulcer, and in severe cases, blindness. The bacteria Moraxella spp. has been described as the...
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ftunivhelsihelda:oai:helda.helsinki.fi:10138/231551 2024-01-07T09:43:11+01:00 Infectious keratoconjunctivitis in semi-domesticated Eurasian tundra reindeer (Rangifer tarandus tarandus) : microbiological study of clinically affected and unaffected animals with special reference to cervid herpesvirus 2 Romano, Javier Sanchez Mork, Torill Laaksonen, Sauli Agren, Erik Nymo, Ingebjorg H. Sunde, Marianne Tryland, Morten Departments of Faculty of Veterinary Medicine Veterinary Biosciences 2018-01-25T09:07:01Z 11 application/pdf http://hdl.handle.net/10138/231551 eng eng BMC 10.1186/s12917-018-1338-y This study was funded by Reindriftens Utviklingsfond (RUF) and Nordic Council of Ministers. The role of the funding bodies was to provide funding as an indirect support to reindeer herders to find new knowledge with regards to the causative agents of an important reindeer disease. Romano , J S , Mork , T , Laaksonen , S , Agren , E , Nymo , I H , Sunde , M & Tryland , M 2018 , ' Infectious keratoconjunctivitis in semi-domesticated Eurasian tundra reindeer (Rangifer tarandus tarandus) : microbiological study of clinically affected and unaffected animals with special reference to cervid herpesvirus 2 ' , BMC Veterinary Research , vol. 14 , 15 . https://doi.org/10.1186/s12917-018-1338-y 85040645804 78550e48-5d35-4456-abf4-9b2a6366fc32 http://hdl.handle.net/10138/231551 000419978000001 cc_by openAccess info:eu-repo/semantics/openAccess Alphaherpesvirus Gammaherpesvirus Pestivirus Bacteria Eye disease IKC Microbiology Reindeer MALIGNANT CATARRHAL FEVER BOVINE KERATOCONJUNCTIVITIS MORAXELLA-BOVOCULI MYCOPLASMA-CONJUNCTIVAE NORTHERN NORWAY MULE DEER ASSOCIATION CALVES SHEEP EYES 413 Veterinary science Article publishedVersion 2018 ftunivhelsihelda 2023-12-14T00:07:39Z Background: Infectious keratoconjunctivitis (IKC) is one of the most common ocular diseases in ruminants worldwide. In addition to keratitis and conjunctivitis, animals with IKC can develop uveitis, corneal ulcer, and in severe cases, blindness. The bacteria Moraxella spp. has been described as the primary causative agent of infectious bovine keratoconjunctivitis (IBK) in cattle (Bos taurus), while Chlamydia spp. and Mycoplasma conjunctivae are considered the main causative agents of IKC in sheep (Ovis aries). Previous studies indicated cervid herpesvirus 2 (CvHV2) as the primary causative agent of IKC in semi-domesticated reindeer (Rangifer tarandus tarandus). The aim of the study was to investigate the presence and prevalence of potential pathogens for IKC in reindeer, and compare the ocular microbiota of animals with IKC, with apparently healthy animals. Results: Semi-domesticated reindeer (n = 341), with (n = 108) or without (n = 113) ocular clinical signs, or with no information on clinical status (n = 120), were sampled in Norway, Sweden and Finland in 2010-2014. Seroprevalence was 37.4% for alphaherpesvirus (95/254), 3.8% for gammaherpesvirus (8/211) and 7.1% for pestivirus (15/211) (ELISA). PCR analyses of conjunctival swab samples revealed a prevalence of 28.5% for CvHV2 (57/200), 11.9% for Chlamydiaceae (16/135) and 1.0% for M. conjunctivae (2/197). Bacteriological cultivation of 202 conjunctival swab samples revealed bacterial growth from 75.2% of the samples, with Moraxella spp. being isolated from 21.6% (11/51) of the animals with and 5.6% (5/84) without ocular clinical signs. A significant association (p <0.001) existed between the presence of clinical signs of IKC and CvHV2 DNA in the affected eyes, an association that was not present for other microorganisms. Conclusions: These results support the hypothesis that CvHV2 is the primary agent of IKC in semi-domesticated reindeer in Fennoscandia, with Moraxella bovoculi being a secondary candidate, since it was isolated in two different outbreaks ... Article in Journal/Newspaper Fennoscandia Northern Norway Rangifer Rangifer tarandus Tundra HELDA – University of Helsinki Open Repository Norway BMC Veterinary Research 14 1 |
institution |
Open Polar |
collection |
HELDA – University of Helsinki Open Repository |
op_collection_id |
ftunivhelsihelda |
language |
English |
topic |
Alphaherpesvirus Gammaherpesvirus Pestivirus Bacteria Eye disease IKC Microbiology Reindeer MALIGNANT CATARRHAL FEVER BOVINE KERATOCONJUNCTIVITIS MORAXELLA-BOVOCULI MYCOPLASMA-CONJUNCTIVAE NORTHERN NORWAY MULE DEER ASSOCIATION CALVES SHEEP EYES 413 Veterinary science |
spellingShingle |
Alphaherpesvirus Gammaherpesvirus Pestivirus Bacteria Eye disease IKC Microbiology Reindeer MALIGNANT CATARRHAL FEVER BOVINE KERATOCONJUNCTIVITIS MORAXELLA-BOVOCULI MYCOPLASMA-CONJUNCTIVAE NORTHERN NORWAY MULE DEER ASSOCIATION CALVES SHEEP EYES 413 Veterinary science Romano, Javier Sanchez Mork, Torill Laaksonen, Sauli Agren, Erik Nymo, Ingebjorg H. Sunde, Marianne Tryland, Morten Infectious keratoconjunctivitis in semi-domesticated Eurasian tundra reindeer (Rangifer tarandus tarandus) : microbiological study of clinically affected and unaffected animals with special reference to cervid herpesvirus 2 |
topic_facet |
Alphaherpesvirus Gammaherpesvirus Pestivirus Bacteria Eye disease IKC Microbiology Reindeer MALIGNANT CATARRHAL FEVER BOVINE KERATOCONJUNCTIVITIS MORAXELLA-BOVOCULI MYCOPLASMA-CONJUNCTIVAE NORTHERN NORWAY MULE DEER ASSOCIATION CALVES SHEEP EYES 413 Veterinary science |
description |
Background: Infectious keratoconjunctivitis (IKC) is one of the most common ocular diseases in ruminants worldwide. In addition to keratitis and conjunctivitis, animals with IKC can develop uveitis, corneal ulcer, and in severe cases, blindness. The bacteria Moraxella spp. has been described as the primary causative agent of infectious bovine keratoconjunctivitis (IBK) in cattle (Bos taurus), while Chlamydia spp. and Mycoplasma conjunctivae are considered the main causative agents of IKC in sheep (Ovis aries). Previous studies indicated cervid herpesvirus 2 (CvHV2) as the primary causative agent of IKC in semi-domesticated reindeer (Rangifer tarandus tarandus). The aim of the study was to investigate the presence and prevalence of potential pathogens for IKC in reindeer, and compare the ocular microbiota of animals with IKC, with apparently healthy animals. Results: Semi-domesticated reindeer (n = 341), with (n = 108) or without (n = 113) ocular clinical signs, or with no information on clinical status (n = 120), were sampled in Norway, Sweden and Finland in 2010-2014. Seroprevalence was 37.4% for alphaherpesvirus (95/254), 3.8% for gammaherpesvirus (8/211) and 7.1% for pestivirus (15/211) (ELISA). PCR analyses of conjunctival swab samples revealed a prevalence of 28.5% for CvHV2 (57/200), 11.9% for Chlamydiaceae (16/135) and 1.0% for M. conjunctivae (2/197). Bacteriological cultivation of 202 conjunctival swab samples revealed bacterial growth from 75.2% of the samples, with Moraxella spp. being isolated from 21.6% (11/51) of the animals with and 5.6% (5/84) without ocular clinical signs. A significant association (p <0.001) existed between the presence of clinical signs of IKC and CvHV2 DNA in the affected eyes, an association that was not present for other microorganisms. Conclusions: These results support the hypothesis that CvHV2 is the primary agent of IKC in semi-domesticated reindeer in Fennoscandia, with Moraxella bovoculi being a secondary candidate, since it was isolated in two different outbreaks ... |
author2 |
Departments of Faculty of Veterinary Medicine Veterinary Biosciences |
format |
Article in Journal/Newspaper |
author |
Romano, Javier Sanchez Mork, Torill Laaksonen, Sauli Agren, Erik Nymo, Ingebjorg H. Sunde, Marianne Tryland, Morten |
author_facet |
Romano, Javier Sanchez Mork, Torill Laaksonen, Sauli Agren, Erik Nymo, Ingebjorg H. Sunde, Marianne Tryland, Morten |
author_sort |
Romano, Javier Sanchez |
title |
Infectious keratoconjunctivitis in semi-domesticated Eurasian tundra reindeer (Rangifer tarandus tarandus) : microbiological study of clinically affected and unaffected animals with special reference to cervid herpesvirus 2 |
title_short |
Infectious keratoconjunctivitis in semi-domesticated Eurasian tundra reindeer (Rangifer tarandus tarandus) : microbiological study of clinically affected and unaffected animals with special reference to cervid herpesvirus 2 |
title_full |
Infectious keratoconjunctivitis in semi-domesticated Eurasian tundra reindeer (Rangifer tarandus tarandus) : microbiological study of clinically affected and unaffected animals with special reference to cervid herpesvirus 2 |
title_fullStr |
Infectious keratoconjunctivitis in semi-domesticated Eurasian tundra reindeer (Rangifer tarandus tarandus) : microbiological study of clinically affected and unaffected animals with special reference to cervid herpesvirus 2 |
title_full_unstemmed |
Infectious keratoconjunctivitis in semi-domesticated Eurasian tundra reindeer (Rangifer tarandus tarandus) : microbiological study of clinically affected and unaffected animals with special reference to cervid herpesvirus 2 |
title_sort |
infectious keratoconjunctivitis in semi-domesticated eurasian tundra reindeer (rangifer tarandus tarandus) : microbiological study of clinically affected and unaffected animals with special reference to cervid herpesvirus 2 |
publisher |
BMC |
publishDate |
2018 |
url |
http://hdl.handle.net/10138/231551 |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Fennoscandia Northern Norway Rangifer Rangifer tarandus Tundra |
genre_facet |
Fennoscandia Northern Norway Rangifer Rangifer tarandus Tundra |
op_relation |
10.1186/s12917-018-1338-y This study was funded by Reindriftens Utviklingsfond (RUF) and Nordic Council of Ministers. The role of the funding bodies was to provide funding as an indirect support to reindeer herders to find new knowledge with regards to the causative agents of an important reindeer disease. Romano , J S , Mork , T , Laaksonen , S , Agren , E , Nymo , I H , Sunde , M & Tryland , M 2018 , ' Infectious keratoconjunctivitis in semi-domesticated Eurasian tundra reindeer (Rangifer tarandus tarandus) : microbiological study of clinically affected and unaffected animals with special reference to cervid herpesvirus 2 ' , BMC Veterinary Research , vol. 14 , 15 . https://doi.org/10.1186/s12917-018-1338-y 85040645804 78550e48-5d35-4456-abf4-9b2a6366fc32 http://hdl.handle.net/10138/231551 000419978000001 |
op_rights |
cc_by openAccess info:eu-repo/semantics/openAccess |
container_title |
BMC Veterinary Research |
container_volume |
14 |
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