Cohort profile : the Nordic Antireflux Surgery Cohort (NordASCo)
Purpose To describe a newly created all-Nordic cohort of patients with gastro-oesophageal reflux disease (GORD), entitled the Nordic Antireflux Surgery Cohort (NordASCo), which will be used to compare participants having undergone antireflux surgery with those who have not regarding risk of cancers,...
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Online Access: | http://hdl.handle.net/10138/222487 |
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ftunivhelsihelda:oai:helda.helsinki.fi:10138/222487 2024-01-07T09:44:15+01:00 Cohort profile : the Nordic Antireflux Surgery Cohort (NordASCo) Maret-Ouda, John Wahlin, Karl Artama, Miia Brusselaers, Nele Farkkila, Martti Lynge, Elsebeth Mattsson, Fredrik Pukkala, Eero Romundstad, Pal Tryggvadottir, Laufey von Euler-Chelpin, My Lagergren, Jesper Clinicum Department of Medicine University of Helsinki Gastroenterologian yksikkö HUS Abdominal Center 2017-09-11T10:51:01Z 8 application/pdf http://hdl.handle.net/10138/222487 eng eng BMJ Publishing Group Ltd 10.1136/bmjopen-2017-016505 This work was supported by the Swedish Research Council [D0547801], the Swedish Cancer Society [2015/460] and the Nordic Cancer Union [186058]. The grant providers had no role in the design, conduction, analysis or reporting of the cohort. Maret-Ouda , J , Wahlin , K , Artama , M , Brusselaers , N , Farkkila , M , Lynge , E , Mattsson , F , Pukkala , E , Romundstad , P , Tryggvadottir , L , von Euler-Chelpin , M & Lagergren , J 2017 , ' Cohort profile : the Nordic Antireflux Surgery Cohort (NordASCo) ' , BMJ Open , vol. 7 , no. 6 , 016505 . https://doi.org/10.1136/bmjopen-2017-016505 ORCID: /0000-0002-0250-8559/work/39204255 85020680741 c6cd19eb-7287-4124-bc9a-11d5ca4cf66b http://hdl.handle.net/10138/222487 000406391200230 cc_by_nc openAccess info:eu-repo/semantics/openAccess GASTROESOPHAGEAL-REFLUX DISEASE CANCER REGISTRY DATA QUALITY COMPLETENESS COMPARABILITY POPULATION TIMELINESS PREVALENCE VALIDATION VALIDITY 3121 General medicine internal medicine and other clinical medicine Article publishedVersion 2017 ftunivhelsihelda 2023-12-14T00:03:40Z Purpose To describe a newly created all-Nordic cohort of patients with gastro-oesophageal reflux disease (GORD), entitled the Nordic Antireflux Surgery Cohort (NordASCo), which will be used to compare participants having undergone antireflux surgery with those who have not regarding risk of cancers, other diseases and mortality. Participants Included were individuals with a GORD diagnosis recorded in any of the nationwide patient registries in the Nordic countries (Denmark, Finland, Iceland, Norway and Sweden) in 1964-2014 (with various start and end years in different countries). Data regarding cancer, other diseases and mortality were retrieved from the nationwide registries for cancer, patients and causes of death, respectively. Findings to date The NordASCo includes 945 153 individuals with a diagnosis of GORD. Of these, 48 433 (5.1%) have undergone primary antireflux surgery. Median age at primary antireflux surgery ranged from 47 to 52 years in the different countries. The coding practices of GORD seem to have differed between the Nordic countries. Future plans The NordASCo will initially be used to analyse the risk of developing known or potential GORDrelated cancers, that is, tumours of the oesophagus, stomach, larynx, pharynx and lung, and to evaluate the mortality in the short-term and long-term perspectives. Additionally, the cohort will be used to evaluate the risk of non-malignant respiratory conditions that might be caused by aspiration of gastric contents. Peer reviewed Article in Journal/Newspaper Iceland HELDA – University of Helsinki Open Repository Norway BMJ Open 7 6 e016505 |
institution |
Open Polar |
collection |
HELDA – University of Helsinki Open Repository |
op_collection_id |
ftunivhelsihelda |
language |
English |
topic |
GASTROESOPHAGEAL-REFLUX DISEASE CANCER REGISTRY DATA QUALITY COMPLETENESS COMPARABILITY POPULATION TIMELINESS PREVALENCE VALIDATION VALIDITY 3121 General medicine internal medicine and other clinical medicine |
spellingShingle |
GASTROESOPHAGEAL-REFLUX DISEASE CANCER REGISTRY DATA QUALITY COMPLETENESS COMPARABILITY POPULATION TIMELINESS PREVALENCE VALIDATION VALIDITY 3121 General medicine internal medicine and other clinical medicine Maret-Ouda, John Wahlin, Karl Artama, Miia Brusselaers, Nele Farkkila, Martti Lynge, Elsebeth Mattsson, Fredrik Pukkala, Eero Romundstad, Pal Tryggvadottir, Laufey von Euler-Chelpin, My Lagergren, Jesper Cohort profile : the Nordic Antireflux Surgery Cohort (NordASCo) |
topic_facet |
GASTROESOPHAGEAL-REFLUX DISEASE CANCER REGISTRY DATA QUALITY COMPLETENESS COMPARABILITY POPULATION TIMELINESS PREVALENCE VALIDATION VALIDITY 3121 General medicine internal medicine and other clinical medicine |
description |
Purpose To describe a newly created all-Nordic cohort of patients with gastro-oesophageal reflux disease (GORD), entitled the Nordic Antireflux Surgery Cohort (NordASCo), which will be used to compare participants having undergone antireflux surgery with those who have not regarding risk of cancers, other diseases and mortality. Participants Included were individuals with a GORD diagnosis recorded in any of the nationwide patient registries in the Nordic countries (Denmark, Finland, Iceland, Norway and Sweden) in 1964-2014 (with various start and end years in different countries). Data regarding cancer, other diseases and mortality were retrieved from the nationwide registries for cancer, patients and causes of death, respectively. Findings to date The NordASCo includes 945 153 individuals with a diagnosis of GORD. Of these, 48 433 (5.1%) have undergone primary antireflux surgery. Median age at primary antireflux surgery ranged from 47 to 52 years in the different countries. The coding practices of GORD seem to have differed between the Nordic countries. Future plans The NordASCo will initially be used to analyse the risk of developing known or potential GORDrelated cancers, that is, tumours of the oesophagus, stomach, larynx, pharynx and lung, and to evaluate the mortality in the short-term and long-term perspectives. Additionally, the cohort will be used to evaluate the risk of non-malignant respiratory conditions that might be caused by aspiration of gastric contents. Peer reviewed |
author2 |
Clinicum Department of Medicine University of Helsinki Gastroenterologian yksikkö HUS Abdominal Center |
format |
Article in Journal/Newspaper |
author |
Maret-Ouda, John Wahlin, Karl Artama, Miia Brusselaers, Nele Farkkila, Martti Lynge, Elsebeth Mattsson, Fredrik Pukkala, Eero Romundstad, Pal Tryggvadottir, Laufey von Euler-Chelpin, My Lagergren, Jesper |
author_facet |
Maret-Ouda, John Wahlin, Karl Artama, Miia Brusselaers, Nele Farkkila, Martti Lynge, Elsebeth Mattsson, Fredrik Pukkala, Eero Romundstad, Pal Tryggvadottir, Laufey von Euler-Chelpin, My Lagergren, Jesper |
author_sort |
Maret-Ouda, John |
title |
Cohort profile : the Nordic Antireflux Surgery Cohort (NordASCo) |
title_short |
Cohort profile : the Nordic Antireflux Surgery Cohort (NordASCo) |
title_full |
Cohort profile : the Nordic Antireflux Surgery Cohort (NordASCo) |
title_fullStr |
Cohort profile : the Nordic Antireflux Surgery Cohort (NordASCo) |
title_full_unstemmed |
Cohort profile : the Nordic Antireflux Surgery Cohort (NordASCo) |
title_sort |
cohort profile : the nordic antireflux surgery cohort (nordasco) |
publisher |
BMJ Publishing Group Ltd |
publishDate |
2017 |
url |
http://hdl.handle.net/10138/222487 |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
10.1136/bmjopen-2017-016505 This work was supported by the Swedish Research Council [D0547801], the Swedish Cancer Society [2015/460] and the Nordic Cancer Union [186058]. The grant providers had no role in the design, conduction, analysis or reporting of the cohort. Maret-Ouda , J , Wahlin , K , Artama , M , Brusselaers , N , Farkkila , M , Lynge , E , Mattsson , F , Pukkala , E , Romundstad , P , Tryggvadottir , L , von Euler-Chelpin , M & Lagergren , J 2017 , ' Cohort profile : the Nordic Antireflux Surgery Cohort (NordASCo) ' , BMJ Open , vol. 7 , no. 6 , 016505 . https://doi.org/10.1136/bmjopen-2017-016505 ORCID: /0000-0002-0250-8559/work/39204255 85020680741 c6cd19eb-7287-4124-bc9a-11d5ca4cf66b http://hdl.handle.net/10138/222487 000406391200230 |
op_rights |
cc_by_nc openAccess info:eu-repo/semantics/openAccess |
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BMJ Open |
container_volume |
7 |
container_issue |
6 |
container_start_page |
e016505 |
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