The Scandinavian Sarcoma Group Central Register : 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma
Purpose - We wanted to examine the potential of the Scandinavian Sarcoma Group (SSG) Central Register, and evaluate referral and treatment practice for soft-tissue sarcomas in the extremities and trunk wall (STS) in the Nordic countries. Background - Based on incidence rates from the literature, 8,1...
Published in: | Acta Orthopaedica |
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2017
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ftunivhelsihelda:oai:helda.helsinki.fi:10138/197464 2024-01-07T09:44:17+01:00 The Scandinavian Sarcoma Group Central Register : 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma Trovik, Clement Bauer, Henrik C. F. Styring, Emelie Sundby Hall, Kirsten Vult von Steyern, Fredrik Eriksson, Sigvard Johansson, Ingela Sampo, Mika Laitinen, Minna Kalen, Anders Jonsson, Halldor Jebsen, Nina Eriksson, Mikael Tukiainen, Erkki Wall, Najme Zaikova, Olga Sigurdsson, Helgi Lehtinen, Tuula Bjerkehagen, Bodil Skorpil, Mikael Eide, Geir Egil Johansson, Elisabeth Alvegard, Thor A. Department of Oncology University of Helsinki Clinicum HUS Comprehensive Cancer Center Department of Surgery Plastiikkakirurgian yksikkö HUS Musculoskeletal and Plastic Surgery 2017-07-05T14:29:01Z 7 application/pdf http://hdl.handle.net/10138/197464 eng eng Taylor & Francis 10.1080/17453674.2017.1293441 The study was supported by the National Advisory Unit on sarcomas in Norway, and by the Swedish Cancer Society. The SSG Central Register is also supported by the National Advisory Unit on sarcomas in Norway and by the Swedish Cancer Society. Trovik , C , Bauer , H C F , Styring , E , Sundby Hall , K , Vult von Steyern , F , Eriksson , S , Johansson , I , Sampo , M , Laitinen , M , Kalen , A , Jonsson , H , Jebsen , N , Eriksson , M , Tukiainen , E , Wall , N , Zaikova , O , Sigurdsson , H , Lehtinen , T , Bjerkehagen , B , Skorpil , M , Eide , G E , Johansson , E & Alvegard , T A 2017 , ' The Scandinavian Sarcoma Group Central Register : 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma ' , Acta Orthopaedica , vol. 88 , no. 3 , pp. 341-347 . https://doi.org/10.1080/17453674.2017.1293441 ORCID: /0000-0002-9975-0121/work/45627056 85014579273 2ccd4f43-c04f-4d61-93e9-f6b17cb1cd79 http://hdl.handle.net/10138/197464 000400742500018 cc_by_nc openAccess info:eu-repo/semantics/openAccess EPIDEMIOLOGY MALIGNANCY REGARDLESS 3126 Surgery anesthesiology intensive care radiology 3122 Cancers Article publishedVersion 2017 ftunivhelsihelda 2023-12-14T00:15:37Z Purpose - We wanted to examine the potential of the Scandinavian Sarcoma Group (SSG) Central Register, and evaluate referral and treatment practice for soft-tissue sarcomas in the extremities and trunk wall (STS) in the Nordic countries. Background - Based on incidence rates from the literature, 8,150 (7,000-9,300) cases of STS of the extremity and trunk wall should have been diagnosed in Norway, Finland, Iceland, and Sweden from 1987 through 2011. The SSG Register has 6,027 cases registered from this period, with 5,837 having complete registration of key variables. 10 centers have been reporting to the Register. The 5 centers that consistently report treat approximately 90% of the cases in their respective regions. The remaining centers have reported all the patients who were treated during certain time periods, but not for the entire 25-year period. Results - 59% of patients were referred to a sarcoma center untouched, i.e. before any attempt at open biopsy. There was an improvement from 52% during the first 5 years to 70% during the last 5 years. 50% had wide or better margins at surgery. Wide margins are now achieved less often than 20 years ago, in parallel with an increase in the use of radiotherapy. For the centers that consistently report, 97% of surviving patients are followed for more than 4 years. Metastasis-free survival (MFS) increased from 67% to 73% during the 25-year period. Interpretation - The Register is considered to be representative of extremity and trunk wall sarcoma disease in the population of Scandinavia, treated at the reporting centers. There were no clinically significant differences in treatment results at these centers. Peer reviewed Article in Journal/Newspaper Iceland HELDA – University of Helsinki Open Repository Norway Acta Orthopaedica 88 3 341 347 |
institution |
Open Polar |
collection |
HELDA – University of Helsinki Open Repository |
op_collection_id |
ftunivhelsihelda |
language |
English |
topic |
EPIDEMIOLOGY MALIGNANCY REGARDLESS 3126 Surgery anesthesiology intensive care radiology 3122 Cancers |
spellingShingle |
EPIDEMIOLOGY MALIGNANCY REGARDLESS 3126 Surgery anesthesiology intensive care radiology 3122 Cancers Trovik, Clement Bauer, Henrik C. F. Styring, Emelie Sundby Hall, Kirsten Vult von Steyern, Fredrik Eriksson, Sigvard Johansson, Ingela Sampo, Mika Laitinen, Minna Kalen, Anders Jonsson, Halldor Jebsen, Nina Eriksson, Mikael Tukiainen, Erkki Wall, Najme Zaikova, Olga Sigurdsson, Helgi Lehtinen, Tuula Bjerkehagen, Bodil Skorpil, Mikael Eide, Geir Egil Johansson, Elisabeth Alvegard, Thor A. The Scandinavian Sarcoma Group Central Register : 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma |
topic_facet |
EPIDEMIOLOGY MALIGNANCY REGARDLESS 3126 Surgery anesthesiology intensive care radiology 3122 Cancers |
description |
Purpose - We wanted to examine the potential of the Scandinavian Sarcoma Group (SSG) Central Register, and evaluate referral and treatment practice for soft-tissue sarcomas in the extremities and trunk wall (STS) in the Nordic countries. Background - Based on incidence rates from the literature, 8,150 (7,000-9,300) cases of STS of the extremity and trunk wall should have been diagnosed in Norway, Finland, Iceland, and Sweden from 1987 through 2011. The SSG Register has 6,027 cases registered from this period, with 5,837 having complete registration of key variables. 10 centers have been reporting to the Register. The 5 centers that consistently report treat approximately 90% of the cases in their respective regions. The remaining centers have reported all the patients who were treated during certain time periods, but not for the entire 25-year period. Results - 59% of patients were referred to a sarcoma center untouched, i.e. before any attempt at open biopsy. There was an improvement from 52% during the first 5 years to 70% during the last 5 years. 50% had wide or better margins at surgery. Wide margins are now achieved less often than 20 years ago, in parallel with an increase in the use of radiotherapy. For the centers that consistently report, 97% of surviving patients are followed for more than 4 years. Metastasis-free survival (MFS) increased from 67% to 73% during the 25-year period. Interpretation - The Register is considered to be representative of extremity and trunk wall sarcoma disease in the population of Scandinavia, treated at the reporting centers. There were no clinically significant differences in treatment results at these centers. Peer reviewed |
author2 |
Department of Oncology University of Helsinki Clinicum HUS Comprehensive Cancer Center Department of Surgery Plastiikkakirurgian yksikkö HUS Musculoskeletal and Plastic Surgery |
format |
Article in Journal/Newspaper |
author |
Trovik, Clement Bauer, Henrik C. F. Styring, Emelie Sundby Hall, Kirsten Vult von Steyern, Fredrik Eriksson, Sigvard Johansson, Ingela Sampo, Mika Laitinen, Minna Kalen, Anders Jonsson, Halldor Jebsen, Nina Eriksson, Mikael Tukiainen, Erkki Wall, Najme Zaikova, Olga Sigurdsson, Helgi Lehtinen, Tuula Bjerkehagen, Bodil Skorpil, Mikael Eide, Geir Egil Johansson, Elisabeth Alvegard, Thor A. |
author_facet |
Trovik, Clement Bauer, Henrik C. F. Styring, Emelie Sundby Hall, Kirsten Vult von Steyern, Fredrik Eriksson, Sigvard Johansson, Ingela Sampo, Mika Laitinen, Minna Kalen, Anders Jonsson, Halldor Jebsen, Nina Eriksson, Mikael Tukiainen, Erkki Wall, Najme Zaikova, Olga Sigurdsson, Helgi Lehtinen, Tuula Bjerkehagen, Bodil Skorpil, Mikael Eide, Geir Egil Johansson, Elisabeth Alvegard, Thor A. |
author_sort |
Trovik, Clement |
title |
The Scandinavian Sarcoma Group Central Register : 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma |
title_short |
The Scandinavian Sarcoma Group Central Register : 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma |
title_full |
The Scandinavian Sarcoma Group Central Register : 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma |
title_fullStr |
The Scandinavian Sarcoma Group Central Register : 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma |
title_full_unstemmed |
The Scandinavian Sarcoma Group Central Register : 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma |
title_sort |
scandinavian sarcoma group central register : 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma |
publisher |
Taylor & Francis |
publishDate |
2017 |
url |
http://hdl.handle.net/10138/197464 |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
10.1080/17453674.2017.1293441 The study was supported by the National Advisory Unit on sarcomas in Norway, and by the Swedish Cancer Society. The SSG Central Register is also supported by the National Advisory Unit on sarcomas in Norway and by the Swedish Cancer Society. Trovik , C , Bauer , H C F , Styring , E , Sundby Hall , K , Vult von Steyern , F , Eriksson , S , Johansson , I , Sampo , M , Laitinen , M , Kalen , A , Jonsson , H , Jebsen , N , Eriksson , M , Tukiainen , E , Wall , N , Zaikova , O , Sigurdsson , H , Lehtinen , T , Bjerkehagen , B , Skorpil , M , Eide , G E , Johansson , E & Alvegard , T A 2017 , ' The Scandinavian Sarcoma Group Central Register : 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma ' , Acta Orthopaedica , vol. 88 , no. 3 , pp. 341-347 . https://doi.org/10.1080/17453674.2017.1293441 ORCID: /0000-0002-9975-0121/work/45627056 85014579273 2ccd4f43-c04f-4d61-93e9-f6b17cb1cd79 http://hdl.handle.net/10138/197464 000400742500018 |
op_rights |
cc_by_nc openAccess info:eu-repo/semantics/openAccess |
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Acta Orthopaedica |
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88 |
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3 |
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341 |
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347 |
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