The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays

Introduction: To determine whether a diet of wheat (Triticum aestivum) germ has a radioprotective effect on albino rat (Rattus rattus var. Albinus) myocardial tissue. Method: Rats between 200 and 250 g were divided into 4 groups of 6 each: Two groups were fed either a wheat diet or regular diet 16 d...

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Published in:Ars Pharmaceutica (Internet)
Main Authors: Bayona Caballero, María Esther, Alayo Zavaleta, Judith, Lombardi Pérez, César Leopoldo, Marín Tello, Carmen Luisa
Format: Article in Journal/Newspaper
Language:English
Published: Editorial Universidad de Granada 2019
Subjects:
Online Access:https://revistaseug.ugr.es/index.php/ars/article/view/10226
https://doi.org/10.30827/ars.v60i4.10226
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spelling ftunivgranadaojs:oai:ojs.revistaseug.ugr.es:article/10226 2023-05-15T18:05:18+02:00 The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays Efecto radioprotector de una dieta de germen de trigo en tejido miocárdico de ratas expuestas a rayos X Bayona Caballero, María Esther Alayo Zavaleta, Judith Lombardi Pérez, César Leopoldo Marín Tello, Carmen Luisa 2019-12-20 application/pdf https://revistaseug.ugr.es/index.php/ars/article/view/10226 https://doi.org/10.30827/ars.v60i4.10226 eng eng Editorial Universidad de Granada https://revistaseug.ugr.es/index.php/ars/article/view/10226/9414 https://revistaseug.ugr.es/index.php/ars/article/view/10226 doi:10.30827/ars.v60i4.10226 Ars Pharmaceutica (Internet); Vol. 60 Núm. 4 (2019); 2013-218 Ars Pharmaceutica (Internet); Vol. 60 No. 4 (2019); 2013-218 2340-9894 0004-2927 Triticum X-Rays heart Trigo Rayos X Corazón info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2019 ftunivgranadaojs https://doi.org/10.30827/ars.v60i4.10226 2022-03-10T17:12:36Z Introduction: To determine whether a diet of wheat (Triticum aestivum) germ has a radioprotective effect on albino rat (Rattus rattus var. Albinus) myocardial tissue. Method: Rats between 200 and 250 g were divided into 4 groups of 6 each: Two groups were fed either a wheat diet or regular diet 16 days before and after a single exposure to 18 mSv of X-rays. The other two groups were fed the same diets but not exposed to X-rays. The animals were sacrificed, and heart tissue was submitted to histopathological study. Results: Rats fed a standard diet and exposed to X-rays presented marked hyperemia of blood vessels, necrosis, presence of connective tissue fibrocytes, loss of muscle architecture and radial arrangement. Exposed rats fed a wheat diet presented with only light necrosis and the presence of fibrocytes. Rats not exposed to X-rays had healthy myocardia. Conclusions: Wheat germ diet may have a radioprotective effect on rat myocardium. Introducción: Determinar si una dieta con germen de trigo (Triticum aestivum) tiene un efecto radio protector sobre el tejido miocárdico de ratas albinas (Rattus rattus var. Albinus) Método: Ratas con un peso entre 200 - 250 g fueron divididas en 4 grupos de 6 cada uno: Dos grupos fueron alimentadas con una dieta regular de germen de trigo durante 16 días antes y después de una única exposición a un grupo con 18 mSv de rayos X. Los otros dos grupos fueron alimentados con una dieta estándar, uno de ellos, fue expuesto a los rayos X. Los animales fueron sacrificados y se realizó un estudio histopatológico del tejido cardiaco. Resultados: Las ratas alimentadas con una dieta estándar y expuesta a los rayos X, presentaron marcada hiperemia de vasos sanguíneos, necrosis, presencia de fibrocitos en el tejido conectivo, pérdida de la arquitectura y disposición radial muscular. Las ratas expuestas y alimentadas con dieta de trigo presentaron solo una ligera necrosis y presencia de fibrocitos. Las ratas no expuestas a rayos X presentaron un miocardio saludable. Conclusiones: La dieta del germen de trigo puede tener un efecto radioprotector sobre el miocardio de rata. Article in Journal/Newspaper Rattus rattus Portal de revistas de la Universidad de Granada Rata ENVELOPE(19.216,19.216,69.928,69.928) Protector ENVELOPE(-66.217,-66.217,-66.717,-66.717) Expuesta ENVELOPE(-63.715,-63.715,-64.867,-64.867) Ars Pharmaceutica (Internet) 60 4
institution Open Polar
collection Portal de revistas de la Universidad de Granada
op_collection_id ftunivgranadaojs
language English
topic Triticum
X-Rays
heart
Trigo
Rayos X
Corazón
spellingShingle Triticum
X-Rays
heart
Trigo
Rayos X
Corazón
Bayona Caballero, María Esther
Alayo Zavaleta, Judith
Lombardi Pérez, César Leopoldo
Marín Tello, Carmen Luisa
The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays
topic_facet Triticum
X-Rays
heart
Trigo
Rayos X
Corazón
description Introduction: To determine whether a diet of wheat (Triticum aestivum) germ has a radioprotective effect on albino rat (Rattus rattus var. Albinus) myocardial tissue. Method: Rats between 200 and 250 g were divided into 4 groups of 6 each: Two groups were fed either a wheat diet or regular diet 16 days before and after a single exposure to 18 mSv of X-rays. The other two groups were fed the same diets but not exposed to X-rays. The animals were sacrificed, and heart tissue was submitted to histopathological study. Results: Rats fed a standard diet and exposed to X-rays presented marked hyperemia of blood vessels, necrosis, presence of connective tissue fibrocytes, loss of muscle architecture and radial arrangement. Exposed rats fed a wheat diet presented with only light necrosis and the presence of fibrocytes. Rats not exposed to X-rays had healthy myocardia. Conclusions: Wheat germ diet may have a radioprotective effect on rat myocardium. Introducción: Determinar si una dieta con germen de trigo (Triticum aestivum) tiene un efecto radio protector sobre el tejido miocárdico de ratas albinas (Rattus rattus var. Albinus) Método: Ratas con un peso entre 200 - 250 g fueron divididas en 4 grupos de 6 cada uno: Dos grupos fueron alimentadas con una dieta regular de germen de trigo durante 16 días antes y después de una única exposición a un grupo con 18 mSv de rayos X. Los otros dos grupos fueron alimentados con una dieta estándar, uno de ellos, fue expuesto a los rayos X. Los animales fueron sacrificados y se realizó un estudio histopatológico del tejido cardiaco. Resultados: Las ratas alimentadas con una dieta estándar y expuesta a los rayos X, presentaron marcada hiperemia de vasos sanguíneos, necrosis, presencia de fibrocitos en el tejido conectivo, pérdida de la arquitectura y disposición radial muscular. Las ratas expuestas y alimentadas con dieta de trigo presentaron solo una ligera necrosis y presencia de fibrocitos. Las ratas no expuestas a rayos X presentaron un miocardio saludable. Conclusiones: La dieta del germen de trigo puede tener un efecto radioprotector sobre el miocardio de rata.
format Article in Journal/Newspaper
author Bayona Caballero, María Esther
Alayo Zavaleta, Judith
Lombardi Pérez, César Leopoldo
Marín Tello, Carmen Luisa
author_facet Bayona Caballero, María Esther
Alayo Zavaleta, Judith
Lombardi Pérez, César Leopoldo
Marín Tello, Carmen Luisa
author_sort Bayona Caballero, María Esther
title The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays
title_short The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays
title_full The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays
title_fullStr The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays
title_full_unstemmed The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays
title_sort radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to x-rays
publisher Editorial Universidad de Granada
publishDate 2019
url https://revistaseug.ugr.es/index.php/ars/article/view/10226
https://doi.org/10.30827/ars.v60i4.10226
long_lat ENVELOPE(19.216,19.216,69.928,69.928)
ENVELOPE(-66.217,-66.217,-66.717,-66.717)
ENVELOPE(-63.715,-63.715,-64.867,-64.867)
geographic Rata
Protector
Expuesta
geographic_facet Rata
Protector
Expuesta
genre Rattus rattus
genre_facet Rattus rattus
op_source Ars Pharmaceutica (Internet); Vol. 60 Núm. 4 (2019); 2013-218
Ars Pharmaceutica (Internet); Vol. 60 No. 4 (2019); 2013-218
2340-9894
0004-2927
op_relation https://revistaseug.ugr.es/index.php/ars/article/view/10226/9414
https://revistaseug.ugr.es/index.php/ars/article/view/10226
doi:10.30827/ars.v60i4.10226
op_doi https://doi.org/10.30827/ars.v60i4.10226
container_title Ars Pharmaceutica (Internet)
container_volume 60
container_issue 4
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