The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays
Introduction: To determine whether a diet of wheat (Triticum aestivum) germ has a radioprotective effect on albino rat (Rattus rattus var. Albinus) myocardial tissue. Method: Rats between 200 and 250 g were divided into 4 groups of 6 each: Two groups were fed either a wheat diet or regular diet 16 d...
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Editorial Universidad de Granada
2019
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ftunivgranadaojs:oai:ojs.revistaseug.ugr.es:article/10226 2023-05-15T18:05:18+02:00 The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays Efecto radioprotector de una dieta de germen de trigo en tejido miocárdico de ratas expuestas a rayos X Bayona Caballero, María Esther Alayo Zavaleta, Judith Lombardi Pérez, César Leopoldo Marín Tello, Carmen Luisa 2019-12-20 application/pdf https://revistaseug.ugr.es/index.php/ars/article/view/10226 https://doi.org/10.30827/ars.v60i4.10226 eng eng Editorial Universidad de Granada https://revistaseug.ugr.es/index.php/ars/article/view/10226/9414 https://revistaseug.ugr.es/index.php/ars/article/view/10226 doi:10.30827/ars.v60i4.10226 Ars Pharmaceutica (Internet); Vol. 60 Núm. 4 (2019); 2013-218 Ars Pharmaceutica (Internet); Vol. 60 No. 4 (2019); 2013-218 2340-9894 0004-2927 Triticum X-Rays heart Trigo Rayos X Corazón info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2019 ftunivgranadaojs https://doi.org/10.30827/ars.v60i4.10226 2022-03-10T17:12:36Z Introduction: To determine whether a diet of wheat (Triticum aestivum) germ has a radioprotective effect on albino rat (Rattus rattus var. Albinus) myocardial tissue. Method: Rats between 200 and 250 g were divided into 4 groups of 6 each: Two groups were fed either a wheat diet or regular diet 16 days before and after a single exposure to 18 mSv of X-rays. The other two groups were fed the same diets but not exposed to X-rays. The animals were sacrificed, and heart tissue was submitted to histopathological study. Results: Rats fed a standard diet and exposed to X-rays presented marked hyperemia of blood vessels, necrosis, presence of connective tissue fibrocytes, loss of muscle architecture and radial arrangement. Exposed rats fed a wheat diet presented with only light necrosis and the presence of fibrocytes. Rats not exposed to X-rays had healthy myocardia. Conclusions: Wheat germ diet may have a radioprotective effect on rat myocardium. Introducción: Determinar si una dieta con germen de trigo (Triticum aestivum) tiene un efecto radio protector sobre el tejido miocárdico de ratas albinas (Rattus rattus var. Albinus) Método: Ratas con un peso entre 200 - 250 g fueron divididas en 4 grupos de 6 cada uno: Dos grupos fueron alimentadas con una dieta regular de germen de trigo durante 16 días antes y después de una única exposición a un grupo con 18 mSv de rayos X. Los otros dos grupos fueron alimentados con una dieta estándar, uno de ellos, fue expuesto a los rayos X. Los animales fueron sacrificados y se realizó un estudio histopatológico del tejido cardiaco. Resultados: Las ratas alimentadas con una dieta estándar y expuesta a los rayos X, presentaron marcada hiperemia de vasos sanguíneos, necrosis, presencia de fibrocitos en el tejido conectivo, pérdida de la arquitectura y disposición radial muscular. Las ratas expuestas y alimentadas con dieta de trigo presentaron solo una ligera necrosis y presencia de fibrocitos. Las ratas no expuestas a rayos X presentaron un miocardio saludable. Conclusiones: La dieta del germen de trigo puede tener un efecto radioprotector sobre el miocardio de rata. Article in Journal/Newspaper Rattus rattus Portal de revistas de la Universidad de Granada Rata ENVELOPE(19.216,19.216,69.928,69.928) Protector ENVELOPE(-66.217,-66.217,-66.717,-66.717) Expuesta ENVELOPE(-63.715,-63.715,-64.867,-64.867) Ars Pharmaceutica (Internet) 60 4 |
institution |
Open Polar |
collection |
Portal de revistas de la Universidad de Granada |
op_collection_id |
ftunivgranadaojs |
language |
English |
topic |
Triticum X-Rays heart Trigo Rayos X Corazón |
spellingShingle |
Triticum X-Rays heart Trigo Rayos X Corazón Bayona Caballero, María Esther Alayo Zavaleta, Judith Lombardi Pérez, César Leopoldo Marín Tello, Carmen Luisa The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays |
topic_facet |
Triticum X-Rays heart Trigo Rayos X Corazón |
description |
Introduction: To determine whether a diet of wheat (Triticum aestivum) germ has a radioprotective effect on albino rat (Rattus rattus var. Albinus) myocardial tissue. Method: Rats between 200 and 250 g were divided into 4 groups of 6 each: Two groups were fed either a wheat diet or regular diet 16 days before and after a single exposure to 18 mSv of X-rays. The other two groups were fed the same diets but not exposed to X-rays. The animals were sacrificed, and heart tissue was submitted to histopathological study. Results: Rats fed a standard diet and exposed to X-rays presented marked hyperemia of blood vessels, necrosis, presence of connective tissue fibrocytes, loss of muscle architecture and radial arrangement. Exposed rats fed a wheat diet presented with only light necrosis and the presence of fibrocytes. Rats not exposed to X-rays had healthy myocardia. Conclusions: Wheat germ diet may have a radioprotective effect on rat myocardium. Introducción: Determinar si una dieta con germen de trigo (Triticum aestivum) tiene un efecto radio protector sobre el tejido miocárdico de ratas albinas (Rattus rattus var. Albinus) Método: Ratas con un peso entre 200 - 250 g fueron divididas en 4 grupos de 6 cada uno: Dos grupos fueron alimentadas con una dieta regular de germen de trigo durante 16 días antes y después de una única exposición a un grupo con 18 mSv de rayos X. Los otros dos grupos fueron alimentados con una dieta estándar, uno de ellos, fue expuesto a los rayos X. Los animales fueron sacrificados y se realizó un estudio histopatológico del tejido cardiaco. Resultados: Las ratas alimentadas con una dieta estándar y expuesta a los rayos X, presentaron marcada hiperemia de vasos sanguíneos, necrosis, presencia de fibrocitos en el tejido conectivo, pérdida de la arquitectura y disposición radial muscular. Las ratas expuestas y alimentadas con dieta de trigo presentaron solo una ligera necrosis y presencia de fibrocitos. Las ratas no expuestas a rayos X presentaron un miocardio saludable. Conclusiones: La dieta del germen de trigo puede tener un efecto radioprotector sobre el miocardio de rata. |
format |
Article in Journal/Newspaper |
author |
Bayona Caballero, María Esther Alayo Zavaleta, Judith Lombardi Pérez, César Leopoldo Marín Tello, Carmen Luisa |
author_facet |
Bayona Caballero, María Esther Alayo Zavaleta, Judith Lombardi Pérez, César Leopoldo Marín Tello, Carmen Luisa |
author_sort |
Bayona Caballero, María Esther |
title |
The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays |
title_short |
The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays |
title_full |
The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays |
title_fullStr |
The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays |
title_full_unstemmed |
The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays |
title_sort |
radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to x-rays |
publisher |
Editorial Universidad de Granada |
publishDate |
2019 |
url |
https://revistaseug.ugr.es/index.php/ars/article/view/10226 https://doi.org/10.30827/ars.v60i4.10226 |
long_lat |
ENVELOPE(19.216,19.216,69.928,69.928) ENVELOPE(-66.217,-66.217,-66.717,-66.717) ENVELOPE(-63.715,-63.715,-64.867,-64.867) |
geographic |
Rata Protector Expuesta |
geographic_facet |
Rata Protector Expuesta |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_source |
Ars Pharmaceutica (Internet); Vol. 60 Núm. 4 (2019); 2013-218 Ars Pharmaceutica (Internet); Vol. 60 No. 4 (2019); 2013-218 2340-9894 0004-2927 |
op_relation |
https://revistaseug.ugr.es/index.php/ars/article/view/10226/9414 https://revistaseug.ugr.es/index.php/ars/article/view/10226 doi:10.30827/ars.v60i4.10226 |
op_doi |
https://doi.org/10.30827/ars.v60i4.10226 |
container_title |
Ars Pharmaceutica (Internet) |
container_volume |
60 |
container_issue |
4 |
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1766176762325106688 |