Grey wolf genomic history reveals a dual ancestry of dogs
The grey wolf (Canis lupus) was the first species to give rise to a domestic population, and they remained widespread throughout the last Ice Age when many other large mammal species went extinct. Little is known, however, about the history and possible extinction of past wolf populations or when an...
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Online Access: | https://biblio.ugent.be/publication/8761018 http://hdl.handle.net/1854/LU-8761018 https://doi.org/10.1038/s41586-022-04824-9 https://biblio.ugent.be/publication/8761018/file/01GVR4Q9GSSZ6B6W04VQV5VZ49 |
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ftunivgent:oai:archive.ugent.be:8761018 2024-01-07T09:42:36+01:00 Grey wolf genomic history reveals a dual ancestry of dogs Bergstrom, Anders Stanton, David W. G. Taron, Ulrike H. Frantz, Laurent Sinding, Mikkel-Holger S. Ersmark, Erik Pfrengle, Saskia Cassatt-Johnstone, Molly Lebrasseur, Ophelie Girdland-Flink, Linus Fernandes, Daniel M. Ollivier, Morgane Speidel, Leo Gopalakrishnan, Shyam Westbury, Michael V. Ramos-Madrigal, Jazmin Feuerborn, Tatiana R. Reiter, Ella Gretzinger, Joscha Muenzel, Susanne C. Swali, Pooja Conard, Nicholas J. Caroe, Christian Haile, James Linderholm, Anna Androsov, Semyon Barnes, Ian Baumann, Chris Benecke, Norbert Bocherens, Herve Brace, Selina Carden, Ruth F. Drucker, Dorothee G. Fedorov, Sergey Gasparik, Mihaly Germonpre, Mietje Grigoriev, Semyon Groves, Pam Hertwig, Stefan T. Ivanova, Varvara V. Janssens, Luc Jennings, Richard P. Kasparov, Aleksei K. Kirillova, Irina V. Kurmaniyazov, Islam Kuzmin, Yaroslav V. Kosintsev, Pavel A. Laznickova-Galetova, Martina Leduc, Charlotte Nikolskiy, Pavel Nussbaumer, Marc O'Drisceoil, Coilin Orlando, Ludovic Outram, Alan Pavlova, Elena Y. Perri, Angela R. Pilot, Malgorzata Pitulko, Vladimir V. Plotnikov, Valerii V. Protopopov, Albert V. Rehazek, Andre Sablin, Mikhail Seguin-Orlando, Andaine Stora, Jan Verjux, Christian Zaibert, Victor F. Zazula, Grant Crombé, Philippe Hansen, Anders J. Willerslev, Eske Leonard, Jennifer A. Gotherstrom, Anders Pinhasi, Ron Schuenemann, Verena J. Hofreiter, Michael Gilbert, M. Thomas P. Shapiro, Beth Larson, Greger Krause, Johannes Dalen, Love Skoglund, Pontus 2022 application/pdf https://biblio.ugent.be/publication/8761018 http://hdl.handle.net/1854/LU-8761018 https://doi.org/10.1038/s41586-022-04824-9 https://biblio.ugent.be/publication/8761018/file/01GVR4Q9GSSZ6B6W04VQV5VZ49 eng eng https://biblio.ugent.be/publication/8761018 http://hdl.handle.net/1854/LU-8761018 http://doi.org/10.1038/s41586-022-04824-9 https://biblio.ugent.be/publication/8761018/file/01GVR4Q9GSSZ6B6W04VQV5VZ49 Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) info:eu-repo/semantics/openAccess NATURE ISSN: 0028-0836 ISSN: 1476-4687 History and Archaeology Biology and Life Sciences COMPLETE MITOCHONDRIAL GENOME ANCIENT DNA EVOLUTIONARY HISTORY LIBRARY PREPARATION SEQUENCE ADMIXTURE ORIGIN CONTAMINATION DOMESTICATION WOLVES journalArticle info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2022 ftunivgent https://doi.org/10.1038/s41586-022-04824-9 2023-12-13T23:07:11Z The grey wolf (Canis lupus) was the first species to give rise to a domestic population, and they remained widespread throughout the last Ice Age when many other large mammal species went extinct. Little is known, however, about the history and possible extinction of past wolf populations or when and where the wolf progenitors of the present-day dog lineage (Canisfamiliaris) lived(1-8). Here we analysed 72 ancient wolf genomes spanning the last 100,000 years from Europe, Siberia and North America. We found that wolf populations were highly connected throughout the Late Pleistocene, with levels of differentiation an order of magnitude lower than they are today. This population connectivity allowed us to detect natural selection across the time series, including rapid fixation of mutations in the gene IFT8840,000-30,000 years ago. We show that dogs are overall more closely related to ancient wolves from eastern Eurasia than to those from western Eurasia, suggesting a domestication process in the east. However, we also found that dogs in the Near East and Africa derive up to half of their ancestry from a distinct population related to modern southwest Eurasian wolves, reflecting either an independent domestication process or admixture from local wolves. None of the analysed ancient wolf genomes is a direct match for either of these dog ancestries, meaning that the exact progenitor populations remain to be located. Article in Journal/Newspaper Canis lupus Siberia Ghent University Academic Bibliography Nature 607 7918 313 320 |
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Open Polar |
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Ghent University Academic Bibliography |
op_collection_id |
ftunivgent |
language |
English |
topic |
History and Archaeology Biology and Life Sciences COMPLETE MITOCHONDRIAL GENOME ANCIENT DNA EVOLUTIONARY HISTORY LIBRARY PREPARATION SEQUENCE ADMIXTURE ORIGIN CONTAMINATION DOMESTICATION WOLVES |
spellingShingle |
History and Archaeology Biology and Life Sciences COMPLETE MITOCHONDRIAL GENOME ANCIENT DNA EVOLUTIONARY HISTORY LIBRARY PREPARATION SEQUENCE ADMIXTURE ORIGIN CONTAMINATION DOMESTICATION WOLVES Bergstrom, Anders Stanton, David W. G. Taron, Ulrike H. Frantz, Laurent Sinding, Mikkel-Holger S. Ersmark, Erik Pfrengle, Saskia Cassatt-Johnstone, Molly Lebrasseur, Ophelie Girdland-Flink, Linus Fernandes, Daniel M. Ollivier, Morgane Speidel, Leo Gopalakrishnan, Shyam Westbury, Michael V. Ramos-Madrigal, Jazmin Feuerborn, Tatiana R. Reiter, Ella Gretzinger, Joscha Muenzel, Susanne C. Swali, Pooja Conard, Nicholas J. Caroe, Christian Haile, James Linderholm, Anna Androsov, Semyon Barnes, Ian Baumann, Chris Benecke, Norbert Bocherens, Herve Brace, Selina Carden, Ruth F. Drucker, Dorothee G. Fedorov, Sergey Gasparik, Mihaly Germonpre, Mietje Grigoriev, Semyon Groves, Pam Hertwig, Stefan T. Ivanova, Varvara V. Janssens, Luc Jennings, Richard P. Kasparov, Aleksei K. Kirillova, Irina V. Kurmaniyazov, Islam Kuzmin, Yaroslav V. Kosintsev, Pavel A. Laznickova-Galetova, Martina Leduc, Charlotte Nikolskiy, Pavel Nussbaumer, Marc O'Drisceoil, Coilin Orlando, Ludovic Outram, Alan Pavlova, Elena Y. Perri, Angela R. Pilot, Malgorzata Pitulko, Vladimir V. Plotnikov, Valerii V. Protopopov, Albert V. Rehazek, Andre Sablin, Mikhail Seguin-Orlando, Andaine Stora, Jan Verjux, Christian Zaibert, Victor F. Zazula, Grant Crombé, Philippe Hansen, Anders J. Willerslev, Eske Leonard, Jennifer A. Gotherstrom, Anders Pinhasi, Ron Schuenemann, Verena J. Hofreiter, Michael Gilbert, M. Thomas P. Shapiro, Beth Larson, Greger Krause, Johannes Dalen, Love Skoglund, Pontus Grey wolf genomic history reveals a dual ancestry of dogs |
topic_facet |
History and Archaeology Biology and Life Sciences COMPLETE MITOCHONDRIAL GENOME ANCIENT DNA EVOLUTIONARY HISTORY LIBRARY PREPARATION SEQUENCE ADMIXTURE ORIGIN CONTAMINATION DOMESTICATION WOLVES |
description |
The grey wolf (Canis lupus) was the first species to give rise to a domestic population, and they remained widespread throughout the last Ice Age when many other large mammal species went extinct. Little is known, however, about the history and possible extinction of past wolf populations or when and where the wolf progenitors of the present-day dog lineage (Canisfamiliaris) lived(1-8). Here we analysed 72 ancient wolf genomes spanning the last 100,000 years from Europe, Siberia and North America. We found that wolf populations were highly connected throughout the Late Pleistocene, with levels of differentiation an order of magnitude lower than they are today. This population connectivity allowed us to detect natural selection across the time series, including rapid fixation of mutations in the gene IFT8840,000-30,000 years ago. We show that dogs are overall more closely related to ancient wolves from eastern Eurasia than to those from western Eurasia, suggesting a domestication process in the east. However, we also found that dogs in the Near East and Africa derive up to half of their ancestry from a distinct population related to modern southwest Eurasian wolves, reflecting either an independent domestication process or admixture from local wolves. None of the analysed ancient wolf genomes is a direct match for either of these dog ancestries, meaning that the exact progenitor populations remain to be located. |
format |
Article in Journal/Newspaper |
author |
Bergstrom, Anders Stanton, David W. G. Taron, Ulrike H. Frantz, Laurent Sinding, Mikkel-Holger S. Ersmark, Erik Pfrengle, Saskia Cassatt-Johnstone, Molly Lebrasseur, Ophelie Girdland-Flink, Linus Fernandes, Daniel M. Ollivier, Morgane Speidel, Leo Gopalakrishnan, Shyam Westbury, Michael V. Ramos-Madrigal, Jazmin Feuerborn, Tatiana R. Reiter, Ella Gretzinger, Joscha Muenzel, Susanne C. Swali, Pooja Conard, Nicholas J. Caroe, Christian Haile, James Linderholm, Anna Androsov, Semyon Barnes, Ian Baumann, Chris Benecke, Norbert Bocherens, Herve Brace, Selina Carden, Ruth F. Drucker, Dorothee G. Fedorov, Sergey Gasparik, Mihaly Germonpre, Mietje Grigoriev, Semyon Groves, Pam Hertwig, Stefan T. Ivanova, Varvara V. Janssens, Luc Jennings, Richard P. Kasparov, Aleksei K. Kirillova, Irina V. Kurmaniyazov, Islam Kuzmin, Yaroslav V. Kosintsev, Pavel A. Laznickova-Galetova, Martina Leduc, Charlotte Nikolskiy, Pavel Nussbaumer, Marc O'Drisceoil, Coilin Orlando, Ludovic Outram, Alan Pavlova, Elena Y. Perri, Angela R. Pilot, Malgorzata Pitulko, Vladimir V. Plotnikov, Valerii V. Protopopov, Albert V. Rehazek, Andre Sablin, Mikhail Seguin-Orlando, Andaine Stora, Jan Verjux, Christian Zaibert, Victor F. Zazula, Grant Crombé, Philippe Hansen, Anders J. Willerslev, Eske Leonard, Jennifer A. Gotherstrom, Anders Pinhasi, Ron Schuenemann, Verena J. Hofreiter, Michael Gilbert, M. Thomas P. Shapiro, Beth Larson, Greger Krause, Johannes Dalen, Love Skoglund, Pontus |
author_facet |
Bergstrom, Anders Stanton, David W. G. Taron, Ulrike H. Frantz, Laurent Sinding, Mikkel-Holger S. Ersmark, Erik Pfrengle, Saskia Cassatt-Johnstone, Molly Lebrasseur, Ophelie Girdland-Flink, Linus Fernandes, Daniel M. Ollivier, Morgane Speidel, Leo Gopalakrishnan, Shyam Westbury, Michael V. Ramos-Madrigal, Jazmin Feuerborn, Tatiana R. Reiter, Ella Gretzinger, Joscha Muenzel, Susanne C. Swali, Pooja Conard, Nicholas J. Caroe, Christian Haile, James Linderholm, Anna Androsov, Semyon Barnes, Ian Baumann, Chris Benecke, Norbert Bocherens, Herve Brace, Selina Carden, Ruth F. Drucker, Dorothee G. Fedorov, Sergey Gasparik, Mihaly Germonpre, Mietje Grigoriev, Semyon Groves, Pam Hertwig, Stefan T. Ivanova, Varvara V. Janssens, Luc Jennings, Richard P. Kasparov, Aleksei K. Kirillova, Irina V. Kurmaniyazov, Islam Kuzmin, Yaroslav V. Kosintsev, Pavel A. Laznickova-Galetova, Martina Leduc, Charlotte Nikolskiy, Pavel Nussbaumer, Marc O'Drisceoil, Coilin Orlando, Ludovic Outram, Alan Pavlova, Elena Y. Perri, Angela R. Pilot, Malgorzata Pitulko, Vladimir V. Plotnikov, Valerii V. Protopopov, Albert V. Rehazek, Andre Sablin, Mikhail Seguin-Orlando, Andaine Stora, Jan Verjux, Christian Zaibert, Victor F. Zazula, Grant Crombé, Philippe Hansen, Anders J. Willerslev, Eske Leonard, Jennifer A. Gotherstrom, Anders Pinhasi, Ron Schuenemann, Verena J. Hofreiter, Michael Gilbert, M. Thomas P. Shapiro, Beth Larson, Greger Krause, Johannes Dalen, Love Skoglund, Pontus |
author_sort |
Bergstrom, Anders |
title |
Grey wolf genomic history reveals a dual ancestry of dogs |
title_short |
Grey wolf genomic history reveals a dual ancestry of dogs |
title_full |
Grey wolf genomic history reveals a dual ancestry of dogs |
title_fullStr |
Grey wolf genomic history reveals a dual ancestry of dogs |
title_full_unstemmed |
Grey wolf genomic history reveals a dual ancestry of dogs |
title_sort |
grey wolf genomic history reveals a dual ancestry of dogs |
publishDate |
2022 |
url |
https://biblio.ugent.be/publication/8761018 http://hdl.handle.net/1854/LU-8761018 https://doi.org/10.1038/s41586-022-04824-9 https://biblio.ugent.be/publication/8761018/file/01GVR4Q9GSSZ6B6W04VQV5VZ49 |
genre |
Canis lupus Siberia |
genre_facet |
Canis lupus Siberia |
op_source |
NATURE ISSN: 0028-0836 ISSN: 1476-4687 |
op_relation |
https://biblio.ugent.be/publication/8761018 http://hdl.handle.net/1854/LU-8761018 http://doi.org/10.1038/s41586-022-04824-9 https://biblio.ugent.be/publication/8761018/file/01GVR4Q9GSSZ6B6W04VQV5VZ49 |
op_rights |
Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1038/s41586-022-04824-9 |
container_title |
Nature |
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607 |
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7918 |
container_start_page |
313 |
op_container_end_page |
320 |
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1787423627546722304 |