The ethyl acetate extract of the marine edible gastropod Haliotis tuberculata coccinea : a potential source of bioactive compounds
The phylum Mollusca represents one of the largest groups of marine invertebrates. Nowadays, molluscan shellfish belonging to the classes Bivalvia and Gastropoda are of commercial interest for fisheries and aquaculture. Although bioactive properties of bivalve molluscs have been widely investigated a...
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ftunivgent:oai:archive.ugent.be:8729087 2023-06-11T04:15:17+02:00 The ethyl acetate extract of the marine edible gastropod Haliotis tuberculata coccinea : a potential source of bioactive compounds Tortorella, Emiliana Giugliano, Rosa De Troch, Marleen Vlaeminck, Bruno de Vicose, Gercende Courtois de Pascale, Donatella 2021 application/pdf https://biblio.ugent.be/publication/8729087 http://hdl.handle.net/1854/LU-8729087 https://doi.org/10.1007/s10126-021-10073-0 https://biblio.ugent.be/publication/8729087/file/8729090 eng eng https://biblio.ugent.be/publication/8729087 http://hdl.handle.net/1854/LU-8729087 http://dx.doi.org/10.1007/s10126-021-10073-0 https://biblio.ugent.be/publication/8729087/file/8729090 No license (in copyright) info:eu-repo/semantics/restrictedAccess MARINE BIOTECHNOLOGY ISSN: 1436-2228 ISSN: 1436-2236 Biology and Life Sciences ANTIMICROBIAL ACTIVITY FATTY-ACIDS ANTICANCER ACTIVITY ANTHELMINTIC ACTIVITY HAEMONCHUS-CONTORTUS PHENOLIC-COMPOUNDS SOUTHEAST COAST ABALONE BIVALVE ANTIBACTERIAL Molluscs Haliotis tuberculata sp Antimicrobial Anticancer Anthelminthic journalArticle info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2021 ftunivgent https://doi.org/10.1007/s10126-021-10073-0 2023-05-10T22:48:41Z The phylum Mollusca represents one of the largest groups of marine invertebrates. Nowadays, molluscan shellfish belonging to the classes Bivalvia and Gastropoda are of commercial interest for fisheries and aquaculture. Although bioactive properties of bivalve molluscs have been widely investigated and several dietary supplements have been brought to the market, the bioactive potentialities of marine gastropods are poorly documented. The present study investigated the bioactive properties of tissue extracts derived from Haliotis tuberculata coccinea, or "European abalone," an edible abalone species distributed in the Mediterranean Sea and the northeast Atlantic Ocean. A bioactive organic compound-rich extract was obtained using ethyl acetate as extracting solvent. It showed antimicrobial activity towards the methicillin-resistant Staphylococcus epidermidis strain RP62A, the emerging multi-drug-resistant Stenotrophomonas maltophilia D71 and Staphylococcus aureus ATCC 6538P, being the most sensitive strain. It also showed anthelmintic activity, evaluated through the toxicity against the target model helminth Caenorhabditis elegans. In addition, the ethyl acetate extract demonstrated a selective cytotoxic activity on the cancer cell lines A375, MBA-MD 231, HeLa, and MCF7, at the concentration of 250 mu g/mL. The fatty acid composition of the bioactive extract was also investigated through FAME analysis. The fatty acid profile showed 45% of saturated fatty acids (SAFA), 22% of monounsaturated fatty acids (MUFA), and 33% of polyunsaturated fatty acids (PUFA). The presence of some biologically important secondary metabolites in the extract was also analysed, revealing the presence of alkaloids, terpenes, and flavonoids. Article in Journal/Newspaper Northeast Atlantic Ghent University Academic Bibliography Marine Biotechnology 23 6 892 903 |
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Open Polar |
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Ghent University Academic Bibliography |
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ftunivgent |
language |
English |
topic |
Biology and Life Sciences ANTIMICROBIAL ACTIVITY FATTY-ACIDS ANTICANCER ACTIVITY ANTHELMINTIC ACTIVITY HAEMONCHUS-CONTORTUS PHENOLIC-COMPOUNDS SOUTHEAST COAST ABALONE BIVALVE ANTIBACTERIAL Molluscs Haliotis tuberculata sp Antimicrobial Anticancer Anthelminthic |
spellingShingle |
Biology and Life Sciences ANTIMICROBIAL ACTIVITY FATTY-ACIDS ANTICANCER ACTIVITY ANTHELMINTIC ACTIVITY HAEMONCHUS-CONTORTUS PHENOLIC-COMPOUNDS SOUTHEAST COAST ABALONE BIVALVE ANTIBACTERIAL Molluscs Haliotis tuberculata sp Antimicrobial Anticancer Anthelminthic Tortorella, Emiliana Giugliano, Rosa De Troch, Marleen Vlaeminck, Bruno de Vicose, Gercende Courtois de Pascale, Donatella The ethyl acetate extract of the marine edible gastropod Haliotis tuberculata coccinea : a potential source of bioactive compounds |
topic_facet |
Biology and Life Sciences ANTIMICROBIAL ACTIVITY FATTY-ACIDS ANTICANCER ACTIVITY ANTHELMINTIC ACTIVITY HAEMONCHUS-CONTORTUS PHENOLIC-COMPOUNDS SOUTHEAST COAST ABALONE BIVALVE ANTIBACTERIAL Molluscs Haliotis tuberculata sp Antimicrobial Anticancer Anthelminthic |
description |
The phylum Mollusca represents one of the largest groups of marine invertebrates. Nowadays, molluscan shellfish belonging to the classes Bivalvia and Gastropoda are of commercial interest for fisheries and aquaculture. Although bioactive properties of bivalve molluscs have been widely investigated and several dietary supplements have been brought to the market, the bioactive potentialities of marine gastropods are poorly documented. The present study investigated the bioactive properties of tissue extracts derived from Haliotis tuberculata coccinea, or "European abalone," an edible abalone species distributed in the Mediterranean Sea and the northeast Atlantic Ocean. A bioactive organic compound-rich extract was obtained using ethyl acetate as extracting solvent. It showed antimicrobial activity towards the methicillin-resistant Staphylococcus epidermidis strain RP62A, the emerging multi-drug-resistant Stenotrophomonas maltophilia D71 and Staphylococcus aureus ATCC 6538P, being the most sensitive strain. It also showed anthelmintic activity, evaluated through the toxicity against the target model helminth Caenorhabditis elegans. In addition, the ethyl acetate extract demonstrated a selective cytotoxic activity on the cancer cell lines A375, MBA-MD 231, HeLa, and MCF7, at the concentration of 250 mu g/mL. The fatty acid composition of the bioactive extract was also investigated through FAME analysis. The fatty acid profile showed 45% of saturated fatty acids (SAFA), 22% of monounsaturated fatty acids (MUFA), and 33% of polyunsaturated fatty acids (PUFA). The presence of some biologically important secondary metabolites in the extract was also analysed, revealing the presence of alkaloids, terpenes, and flavonoids. |
format |
Article in Journal/Newspaper |
author |
Tortorella, Emiliana Giugliano, Rosa De Troch, Marleen Vlaeminck, Bruno de Vicose, Gercende Courtois de Pascale, Donatella |
author_facet |
Tortorella, Emiliana Giugliano, Rosa De Troch, Marleen Vlaeminck, Bruno de Vicose, Gercende Courtois de Pascale, Donatella |
author_sort |
Tortorella, Emiliana |
title |
The ethyl acetate extract of the marine edible gastropod Haliotis tuberculata coccinea : a potential source of bioactive compounds |
title_short |
The ethyl acetate extract of the marine edible gastropod Haliotis tuberculata coccinea : a potential source of bioactive compounds |
title_full |
The ethyl acetate extract of the marine edible gastropod Haliotis tuberculata coccinea : a potential source of bioactive compounds |
title_fullStr |
The ethyl acetate extract of the marine edible gastropod Haliotis tuberculata coccinea : a potential source of bioactive compounds |
title_full_unstemmed |
The ethyl acetate extract of the marine edible gastropod Haliotis tuberculata coccinea : a potential source of bioactive compounds |
title_sort |
ethyl acetate extract of the marine edible gastropod haliotis tuberculata coccinea : a potential source of bioactive compounds |
publishDate |
2021 |
url |
https://biblio.ugent.be/publication/8729087 http://hdl.handle.net/1854/LU-8729087 https://doi.org/10.1007/s10126-021-10073-0 https://biblio.ugent.be/publication/8729087/file/8729090 |
genre |
Northeast Atlantic |
genre_facet |
Northeast Atlantic |
op_source |
MARINE BIOTECHNOLOGY ISSN: 1436-2228 ISSN: 1436-2236 |
op_relation |
https://biblio.ugent.be/publication/8729087 http://hdl.handle.net/1854/LU-8729087 http://dx.doi.org/10.1007/s10126-021-10073-0 https://biblio.ugent.be/publication/8729087/file/8729090 |
op_rights |
No license (in copyright) info:eu-repo/semantics/restrictedAccess |
op_doi |
https://doi.org/10.1007/s10126-021-10073-0 |
container_title |
Marine Biotechnology |
container_volume |
23 |
container_issue |
6 |
container_start_page |
892 |
op_container_end_page |
903 |
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1768371968255459328 |