Acute and chronic effects of endosulfan on the haemato-immunological and histopathological responses of a threatened freshwater fish, spotted murrel, Channa punctatus
Two experiments, one short-term and one long-term, were conducted to elucidate the acute and chronic effects, respectively, of endosulfan exposure on the haemato-immunological and histopathological responses of Channa puncatatus. In the short-term study, fish were exposed to sublethal endosulfan (8....
Published in: | Fish Physiology and Biochemistry |
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2012
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Online Access: | https://biblio.ugent.be/publication/4140957 http://hdl.handle.net/1854/LU-4140957 https://doi.org/10.1007/s10695-011-9530-z https://biblio.ugent.be/publication/4140957/file/4140966 |
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ftunivgent:oai:archive.ugent.be:4140957 2023-06-11T04:16:21+02:00 Acute and chronic effects of endosulfan on the haemato-immunological and histopathological responses of a threatened freshwater fish, spotted murrel, Channa punctatus Sarma, Kamal Pal, AK Sahu, NP Dalvi, RS Chatterjee, Nirupama Mukherjee, SC Baruah, Sri Kartik 2012 application/pdf https://biblio.ugent.be/publication/4140957 http://hdl.handle.net/1854/LU-4140957 https://doi.org/10.1007/s10695-011-9530-z https://biblio.ugent.be/publication/4140957/file/4140966 eng eng https://biblio.ugent.be/publication/4140957 http://hdl.handle.net/1854/LU-4140957 http://dx.doi.org/10.1007/s10695-011-9530-z https://biblio.ugent.be/publication/4140957/file/4140966 No license (in copyright) info:eu-repo/semantics/restrictedAccess FISH PHYSIOLOGY AND BIOCHEMISTRY ISSN: 0920-1742 Biology and Life Sciences Haematology Histology Channa punctatus Endosulfan Immune responses CARP CYPRINUS-CARPIO SALMON SALMO-SALAR SUBLETHAL CONCENTRATIONS HEMATOLOGICAL INDEXES DIETARY ENDOSULFAN IMMUNE-RESPONSE ASCORBIC-ACID COMMON CARP TOXICITY PARAMETERS journalArticle info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2012 ftunivgent https://doi.org/10.1007/s10695-011-9530-z 2023-05-10T22:33:06Z Two experiments, one short-term and one long-term, were conducted to elucidate the acute and chronic effects, respectively, of endosulfan exposure on the haemato-immunological and histopathological responses of Channa puncatatus. In the short-term study, fish were exposed to sublethal endosulfan (8.1 mu g l(-1)) for 12, 24, 36, 48, 72 and 96 h. In the long-term study, fish were fed with normal diet and simultaneously either exposed to endosulfan (1.2 mu g l(-1)) for 90 days or not. Results showed that the ascorbic acid levels in both the liver and the muscle decreased significantly (P < 0.05) by acute and chronic endosulfan exposure. The haemoglobin (Hb) level reduced significantly (P < 0.05) by 15.5% within 12 h of acute endosulfan exposure, further decreased by 25.8% after 24 h of exposure, however, thereafter the values increased and at the end of 72 h returned to normal levels. Almost similar trend was observed for the erythrocyte (RBC) count. The WBC count and the nitroblue tetrazolium (NBT) value showed a general increasing trend with increase in the duration of acute endosulfan exposure. The chronic exposure of C. punctatus to endosulfan significantly (P < 0.05) lowered the Hb level, RBC and WBC counts, NBT reduction value and the plasma parameters such as plasma protein, albumin (A) and globulin (G) compared with that of the control (except for A/G ratio). Endosulfan exposure also severely altered the liver histological structure. Overall results indicated that both short-term acute and long-term chronic endosulfan exposure had a significant impact on the haemato-immunological parameters and tissue histopathology of C. punctatus. Article in Journal/Newspaper Salmo salar Ghent University Academic Bibliography Fish Physiology and Biochemistry 38 2 499 509 |
institution |
Open Polar |
collection |
Ghent University Academic Bibliography |
op_collection_id |
ftunivgent |
language |
English |
topic |
Biology and Life Sciences Haematology Histology Channa punctatus Endosulfan Immune responses CARP CYPRINUS-CARPIO SALMON SALMO-SALAR SUBLETHAL CONCENTRATIONS HEMATOLOGICAL INDEXES DIETARY ENDOSULFAN IMMUNE-RESPONSE ASCORBIC-ACID COMMON CARP TOXICITY PARAMETERS |
spellingShingle |
Biology and Life Sciences Haematology Histology Channa punctatus Endosulfan Immune responses CARP CYPRINUS-CARPIO SALMON SALMO-SALAR SUBLETHAL CONCENTRATIONS HEMATOLOGICAL INDEXES DIETARY ENDOSULFAN IMMUNE-RESPONSE ASCORBIC-ACID COMMON CARP TOXICITY PARAMETERS Sarma, Kamal Pal, AK Sahu, NP Dalvi, RS Chatterjee, Nirupama Mukherjee, SC Baruah, Sri Kartik Acute and chronic effects of endosulfan on the haemato-immunological and histopathological responses of a threatened freshwater fish, spotted murrel, Channa punctatus |
topic_facet |
Biology and Life Sciences Haematology Histology Channa punctatus Endosulfan Immune responses CARP CYPRINUS-CARPIO SALMON SALMO-SALAR SUBLETHAL CONCENTRATIONS HEMATOLOGICAL INDEXES DIETARY ENDOSULFAN IMMUNE-RESPONSE ASCORBIC-ACID COMMON CARP TOXICITY PARAMETERS |
description |
Two experiments, one short-term and one long-term, were conducted to elucidate the acute and chronic effects, respectively, of endosulfan exposure on the haemato-immunological and histopathological responses of Channa puncatatus. In the short-term study, fish were exposed to sublethal endosulfan (8.1 mu g l(-1)) for 12, 24, 36, 48, 72 and 96 h. In the long-term study, fish were fed with normal diet and simultaneously either exposed to endosulfan (1.2 mu g l(-1)) for 90 days or not. Results showed that the ascorbic acid levels in both the liver and the muscle decreased significantly (P < 0.05) by acute and chronic endosulfan exposure. The haemoglobin (Hb) level reduced significantly (P < 0.05) by 15.5% within 12 h of acute endosulfan exposure, further decreased by 25.8% after 24 h of exposure, however, thereafter the values increased and at the end of 72 h returned to normal levels. Almost similar trend was observed for the erythrocyte (RBC) count. The WBC count and the nitroblue tetrazolium (NBT) value showed a general increasing trend with increase in the duration of acute endosulfan exposure. The chronic exposure of C. punctatus to endosulfan significantly (P < 0.05) lowered the Hb level, RBC and WBC counts, NBT reduction value and the plasma parameters such as plasma protein, albumin (A) and globulin (G) compared with that of the control (except for A/G ratio). Endosulfan exposure also severely altered the liver histological structure. Overall results indicated that both short-term acute and long-term chronic endosulfan exposure had a significant impact on the haemato-immunological parameters and tissue histopathology of C. punctatus. |
format |
Article in Journal/Newspaper |
author |
Sarma, Kamal Pal, AK Sahu, NP Dalvi, RS Chatterjee, Nirupama Mukherjee, SC Baruah, Sri Kartik |
author_facet |
Sarma, Kamal Pal, AK Sahu, NP Dalvi, RS Chatterjee, Nirupama Mukherjee, SC Baruah, Sri Kartik |
author_sort |
Sarma, Kamal |
title |
Acute and chronic effects of endosulfan on the haemato-immunological and histopathological responses of a threatened freshwater fish, spotted murrel, Channa punctatus |
title_short |
Acute and chronic effects of endosulfan on the haemato-immunological and histopathological responses of a threatened freshwater fish, spotted murrel, Channa punctatus |
title_full |
Acute and chronic effects of endosulfan on the haemato-immunological and histopathological responses of a threatened freshwater fish, spotted murrel, Channa punctatus |
title_fullStr |
Acute and chronic effects of endosulfan on the haemato-immunological and histopathological responses of a threatened freshwater fish, spotted murrel, Channa punctatus |
title_full_unstemmed |
Acute and chronic effects of endosulfan on the haemato-immunological and histopathological responses of a threatened freshwater fish, spotted murrel, Channa punctatus |
title_sort |
acute and chronic effects of endosulfan on the haemato-immunological and histopathological responses of a threatened freshwater fish, spotted murrel, channa punctatus |
publishDate |
2012 |
url |
https://biblio.ugent.be/publication/4140957 http://hdl.handle.net/1854/LU-4140957 https://doi.org/10.1007/s10695-011-9530-z https://biblio.ugent.be/publication/4140957/file/4140966 |
genre |
Salmo salar |
genre_facet |
Salmo salar |
op_source |
FISH PHYSIOLOGY AND BIOCHEMISTRY ISSN: 0920-1742 |
op_relation |
https://biblio.ugent.be/publication/4140957 http://hdl.handle.net/1854/LU-4140957 http://dx.doi.org/10.1007/s10695-011-9530-z https://biblio.ugent.be/publication/4140957/file/4140966 |
op_rights |
No license (in copyright) info:eu-repo/semantics/restrictedAccess |
op_doi |
https://doi.org/10.1007/s10695-011-9530-z |
container_title |
Fish Physiology and Biochemistry |
container_volume |
38 |
container_issue |
2 |
container_start_page |
499 |
op_container_end_page |
509 |
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1768374058353688576 |