Mortality after surgery in Europe: a 7 day cohort study
BACKGROUND: Clinical outcomes after major surgery are poorly described at the national level. Evidence of heterogeneity between hospitals and health-care systems suggests potential to improve care for patients but this potential remains unconfirmed. The European Surgical Outcomes Study was an intern...
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ftunivgent:oai:archive.ugent.be:3229951 2023-10-01T03:57:00+02:00 Mortality after surgery in Europe: a 7 day cohort study Pearse, Rupert M Moreno, Rui P Bauer, Peter Pelosi, Paolo Metnitz, Philipp Spies, Claudia Vallet, Benoit Vincent, Jean-Louis Hoeft, Andreas Rhodes, Andrew European Surgical Outcomes Study (EuSOS) group, the Hoste, Eric 2012 application/pdf https://biblio.ugent.be/publication/3229951 http://hdl.handle.net/1854/LU-3229951 https://doi.org/10.1016/S0140-6736(12)61148-9 https://biblio.ugent.be/publication/3229951/file/3229962 eng eng https://biblio.ugent.be/publication/3229951 http://hdl.handle.net/1854/LU-3229951 http://dx.doi.org/10.1016/S0140-6736(12)61148-9 https://biblio.ugent.be/publication/3229951/file/3229962 No license (in copyright) info:eu-repo/semantics/restrictedAccess LANCET ISSN: 0140-6736 Medicine and Health Sciences MAJOR SURGERY RISK CANCER-SURGERY INPATIENT SURGERY POSTOPERATIVE COMPLICATIONS CRITICAL-CARE NONCARDIAC SURGERY SURGICAL QUALITY IMPROVEMENT LONG-TERM SURVIVAL POPULATION journalArticle info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2012 ftunivgent https://doi.org/10.1016/S0140-6736(12)61148-9 2023-09-06T22:33:23Z BACKGROUND: Clinical outcomes after major surgery are poorly described at the national level. Evidence of heterogeneity between hospitals and health-care systems suggests potential to improve care for patients but this potential remains unconfirmed. The European Surgical Outcomes Study was an international study designed to assess outcomes after non-cardiac surgery in Europe. METHODS: We did this 7 day cohort study between April 4 and April 11, 2011. We collected data describing consecutive patients aged 16 years and older undergoing inpatient non-cardiac surgery in 498 hospitals across 28 European nations. Patients were followed up for a maximum of 60 days. The primary endpoint was in-hospital mortality. Secondary outcome measures were duration of hospital stay and admission to critical care. We used χ(2) and Fisher's exact tests to compare categorical variables and the t test or the Mann-Whitney U test to compare continuous variables. Significance was set at p<0·05. We constructed multilevel logistic regression models to adjust for the differences in mortality rates between countries. FINDINGS: We included 46,539 patients, of whom 1855 (4%) died before hospital discharge. 3599 (8%) patients were admitted to critical care after surgery with a median length of stay of 1·2 days (IQR 0·9-3·6). 1358 (73%) patients who died were not admitted to critical care at any stage after surgery. Crude mortality rates varied widely between countries (from 1·2% [95% CI 0·0-3·0] for Iceland to 21·5% [16·9-26·2] for Latvia). After adjustment for confounding variables, important differences remained between countries when compared with the UK, the country with the largest dataset (OR range from 0·44 [95% CI 0·19-1·05; p=0·06] for Finland to 6·92 [2·37-20·27; p=0·0004] for Poland). INTERPRETATION: The mortality rate for patients undergoing inpatient non-cardiac surgery was higher than anticipated. Variations in mortality between countries suggest the need for national and international strategies to improve care for this group ... Article in Journal/Newspaper Iceland Ghent University Academic Bibliography The Lancet 380 9847 1059 1065 |
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Open Polar |
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Ghent University Academic Bibliography |
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ftunivgent |
language |
English |
topic |
Medicine and Health Sciences MAJOR SURGERY RISK CANCER-SURGERY INPATIENT SURGERY POSTOPERATIVE COMPLICATIONS CRITICAL-CARE NONCARDIAC SURGERY SURGICAL QUALITY IMPROVEMENT LONG-TERM SURVIVAL POPULATION |
spellingShingle |
Medicine and Health Sciences MAJOR SURGERY RISK CANCER-SURGERY INPATIENT SURGERY POSTOPERATIVE COMPLICATIONS CRITICAL-CARE NONCARDIAC SURGERY SURGICAL QUALITY IMPROVEMENT LONG-TERM SURVIVAL POPULATION Pearse, Rupert M Moreno, Rui P Bauer, Peter Pelosi, Paolo Metnitz, Philipp Spies, Claudia Vallet, Benoit Vincent, Jean-Louis Hoeft, Andreas Rhodes, Andrew European Surgical Outcomes Study (EuSOS) group, the Hoste, Eric Mortality after surgery in Europe: a 7 day cohort study |
topic_facet |
Medicine and Health Sciences MAJOR SURGERY RISK CANCER-SURGERY INPATIENT SURGERY POSTOPERATIVE COMPLICATIONS CRITICAL-CARE NONCARDIAC SURGERY SURGICAL QUALITY IMPROVEMENT LONG-TERM SURVIVAL POPULATION |
description |
BACKGROUND: Clinical outcomes after major surgery are poorly described at the national level. Evidence of heterogeneity between hospitals and health-care systems suggests potential to improve care for patients but this potential remains unconfirmed. The European Surgical Outcomes Study was an international study designed to assess outcomes after non-cardiac surgery in Europe. METHODS: We did this 7 day cohort study between April 4 and April 11, 2011. We collected data describing consecutive patients aged 16 years and older undergoing inpatient non-cardiac surgery in 498 hospitals across 28 European nations. Patients were followed up for a maximum of 60 days. The primary endpoint was in-hospital mortality. Secondary outcome measures were duration of hospital stay and admission to critical care. We used χ(2) and Fisher's exact tests to compare categorical variables and the t test or the Mann-Whitney U test to compare continuous variables. Significance was set at p<0·05. We constructed multilevel logistic regression models to adjust for the differences in mortality rates between countries. FINDINGS: We included 46,539 patients, of whom 1855 (4%) died before hospital discharge. 3599 (8%) patients were admitted to critical care after surgery with a median length of stay of 1·2 days (IQR 0·9-3·6). 1358 (73%) patients who died were not admitted to critical care at any stage after surgery. Crude mortality rates varied widely between countries (from 1·2% [95% CI 0·0-3·0] for Iceland to 21·5% [16·9-26·2] for Latvia). After adjustment for confounding variables, important differences remained between countries when compared with the UK, the country with the largest dataset (OR range from 0·44 [95% CI 0·19-1·05; p=0·06] for Finland to 6·92 [2·37-20·27; p=0·0004] for Poland). INTERPRETATION: The mortality rate for patients undergoing inpatient non-cardiac surgery was higher than anticipated. Variations in mortality between countries suggest the need for national and international strategies to improve care for this group ... |
format |
Article in Journal/Newspaper |
author |
Pearse, Rupert M Moreno, Rui P Bauer, Peter Pelosi, Paolo Metnitz, Philipp Spies, Claudia Vallet, Benoit Vincent, Jean-Louis Hoeft, Andreas Rhodes, Andrew European Surgical Outcomes Study (EuSOS) group, the Hoste, Eric |
author_facet |
Pearse, Rupert M Moreno, Rui P Bauer, Peter Pelosi, Paolo Metnitz, Philipp Spies, Claudia Vallet, Benoit Vincent, Jean-Louis Hoeft, Andreas Rhodes, Andrew European Surgical Outcomes Study (EuSOS) group, the Hoste, Eric |
author_sort |
Pearse, Rupert M |
title |
Mortality after surgery in Europe: a 7 day cohort study |
title_short |
Mortality after surgery in Europe: a 7 day cohort study |
title_full |
Mortality after surgery in Europe: a 7 day cohort study |
title_fullStr |
Mortality after surgery in Europe: a 7 day cohort study |
title_full_unstemmed |
Mortality after surgery in Europe: a 7 day cohort study |
title_sort |
mortality after surgery in europe: a 7 day cohort study |
publishDate |
2012 |
url |
https://biblio.ugent.be/publication/3229951 http://hdl.handle.net/1854/LU-3229951 https://doi.org/10.1016/S0140-6736(12)61148-9 https://biblio.ugent.be/publication/3229951/file/3229962 |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
LANCET ISSN: 0140-6736 |
op_relation |
https://biblio.ugent.be/publication/3229951 http://hdl.handle.net/1854/LU-3229951 http://dx.doi.org/10.1016/S0140-6736(12)61148-9 https://biblio.ugent.be/publication/3229951/file/3229962 |
op_rights |
No license (in copyright) info:eu-repo/semantics/restrictedAccess |
op_doi |
https://doi.org/10.1016/S0140-6736(12)61148-9 |
container_title |
The Lancet |
container_volume |
380 |
container_issue |
9847 |
container_start_page |
1059 |
op_container_end_page |
1065 |
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1778527804534554624 |