Subaortastenose bij de newfoundland: erfelijkheid, pathofysiologie, diagnose, prognose en fokadvies
Subaortic stenosis is a narrowing of the left ventricular outflow tract just below the aortic valve, and is one of the most diagnosed congenital inherited heart diseases in the Newfoundland. The classification of subaortic stenosis is based on the lesions or the findings on echocardiography. Althoug...
| Main Authors: | , , |
|---|---|
| Format: | Article in Journal/Newspaper |
| Language: | Dutch |
| Published: |
2012
|
| Subjects: | |
| Online Access: | https://biblio.ugent.be/publication/3031326 http://hdl.handle.net/1854/LU-3031326 https://biblio.ugent.be/publication/3031326/file/3031398 |
| Summary: | Subaortic stenosis is a narrowing of the left ventricular outflow tract just below the aortic valve, and is one of the most diagnosed congenital inherited heart diseases in the Newfoundland. The classification of subaortic stenosis is based on the lesions or the findings on echocardiography. Although the mode of inheritance is uncertain, a dominant trait with variable penetrance is generally accepted. The Epidermal Growth Factor Receptor oncogene is, together with the Ptim11-gene, a possible candidate gene to be involved in this disease. The diagnosis is particulary based on auscultation and echocardiography. The prognosis is variable and breeding advice is based on echocardiographic screening at the age of eighteen months; however, it remains a difficult issue. |
|---|