Protein-derived bioactives affecting CCK-induced satiety: how to detect untargeted compounds and determine their identity

Cholecystokinin (CCK) is a gut hormone that induces a feeling of satiety and therefore plays an important role in weight regulation. In this minireview, different food proteins and protein hydrolysates will be introduced that are able to enhance CCK-mediated satiety. This mechanism can be influenced...

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Bibliographic Details
Main Authors: Staljanssens, Dorien, Smagghe, Guy, Van Camp, John
Format: Article in Journal/Newspaper
Language:English
Published: 2012
Subjects:
Biology and Life Sciences
satiety
Cholecystokinin
bioactive peptides
protein hydrolysates
CCK1 receptor
COD GADUS-MORHUA
FOOD-INTAKE
CHOLECYSTOKININ SECRETION
STC-1 CELLS
RELEASE
APPETITE
HUMANS
EXPRESSION
PRODUCTS
FISH
Gadus morhua
Online Access:https://biblio.ugent.be/publication/2122228
http://hdl.handle.net/1854/LU-2122228
https://biblio.ugent.be/publication/2122228/file/6771211
Description
Summary:Cholecystokinin (CCK) is a gut hormone that induces a feeling of satiety and therefore plays an important role in weight regulation. In this minireview, different food proteins and protein hydrolysates will be introduced that are able to enhance CCK-mediated satiety. This mechanism can be influenced at three interaction points, namely CCK release, trypsin-sensitive luminal CCK-releasing factors and the CCK receptor. Food components able to affect satiety are very promising ingredients in the development of functional foods that can be used as an aid in the battle against obesity.

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