Elevated water CO2 can prevent dietary-induced osteomalacia in post-smolt Atlantic salmon (Salmo salar, L.)
Expansion of land-based systems in fish farms elevate the content of metabolic carbon dioxide (CO2) in the water. High CO2 is suggested to increase the bone mineral content in Atlantic salmon (Salmo salar, L.). Conversely, low dietary phosphorus (P) halts bone mineralization. This study examines if...
Published in: | Biomolecules |
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Language: | English |
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2023
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Online Access: | https://biblio.ugent.be/publication/01H035F613V87NFT99VTXWZTX4 http://hdl.handle.net/1854/LU-01H035F613V87NFT99VTXWZTX4 https://doi.org/10.3390/biom13040663 https://biblio.ugent.be/publication/01H035F613V87NFT99VTXWZTX4/file/01H035R3W9J1VRKMJC4EF0XZK2 |
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ftunivgent:oai:archive.ugent.be:01H035F613V87NFT99VTXWZTX4 2023-10-01T03:54:34+02:00 Elevated water CO2 can prevent dietary-induced osteomalacia in post-smolt Atlantic salmon (Salmo salar, L.) Drábiková, Lucia Fjelldal, Per Gunnar Yousaf, Muhammad Naveed Morken, Thea De Clercq, Adelbert McGurk, Charles Witten, Paul Eckhard 2023 application/pdf https://biblio.ugent.be/publication/01H035F613V87NFT99VTXWZTX4 http://hdl.handle.net/1854/LU-01H035F613V87NFT99VTXWZTX4 https://doi.org/10.3390/biom13040663 https://biblio.ugent.be/publication/01H035F613V87NFT99VTXWZTX4/file/01H035R3W9J1VRKMJC4EF0XZK2 eng eng info:eu-repo/grantAgreement/EC/H2020/766347 https://biblio.ugent.be/publication/01H035F613V87NFT99VTXWZTX4 http://hdl.handle.net/1854/LU-01H035F613V87NFT99VTXWZTX4 http://dx.doi.org/10.3390/biom13040663 https://biblio.ugent.be/publication/01H035F613V87NFT99VTXWZTX4/file/01H035R3W9J1VRKMJC4EF0XZK2 Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) info:eu-repo/semantics/openAccess BIOMOLECULES ISSN: 2218-273X Biology and Life Sciences Molecular Biology Biochemistry CO2 dietary phosphorus bone mineralization Atlantic salmon skeleton fgf23 TROUT ONCORHYNCHUS-MYKISS DANIO-RERIO OSTARIOPHYSI EARLY SEAWATER PHASE RAINBOW-TROUT CARBON-DIOXIDE VERTEBRAL COLUMN FRESH-WATER NUTRIENT DIGESTIBILITIES OCEAN ACIDIFICATION GROWTH-PERFORMANCE journalArticle info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2023 ftunivgent https://doi.org/10.3390/biom13040663 2023-09-06T22:55:38Z Expansion of land-based systems in fish farms elevate the content of metabolic carbon dioxide (CO2) in the water. High CO2 is suggested to increase the bone mineral content in Atlantic salmon (Salmo salar, L.). Conversely, low dietary phosphorus (P) halts bone mineralization. This study examines if high CO2 can counteract reduced bone mineralization imposed by low dietary P intake. Atlantic salmon post-seawater transfer (initial weight 207.03 g) were fed diets containing 6.3 g/kg (0.5P), 9.0 g/kg (1P), or 26.8 g/kg (3P) total P for 13 weeks. Atlantic salmon from all dietary P groups were reared in seawater which was not injected with CO2 and contained a regular CO2 level (5 mg/L) or in seawater with injected CO2 thus raising the level to 20 mg/L. Atlantic salmon were analyzed for blood chemistry, bone mineral content, vertebral centra deformities, mechanical properties, bone matrix alterations, expression of bone mineralization, and P metabolism-related genes. High CO2 and high P reduced Atlantic salmon growth and feed intake. High CO2 increased bone mineralization when dietary P was low. Atlantic salmon fed with a low P diet downregulated the fgf23 expression in bone cells indicating an increased renal phosphate reabsorption. The current results suggest that reduced dietary P could be sufficient to maintain bone mineralization under conditions of elevated CO2. This opens up a possibility for lowering the dietary P content under certain farming conditions. Article in Journal/Newspaper Atlantic salmon Ocean acidification Salmo salar Ghent University Academic Bibliography Biomolecules 13 4 663 |
institution |
Open Polar |
collection |
Ghent University Academic Bibliography |
op_collection_id |
ftunivgent |
language |
English |
topic |
Biology and Life Sciences Molecular Biology Biochemistry CO2 dietary phosphorus bone mineralization Atlantic salmon skeleton fgf23 TROUT ONCORHYNCHUS-MYKISS DANIO-RERIO OSTARIOPHYSI EARLY SEAWATER PHASE RAINBOW-TROUT CARBON-DIOXIDE VERTEBRAL COLUMN FRESH-WATER NUTRIENT DIGESTIBILITIES OCEAN ACIDIFICATION GROWTH-PERFORMANCE |
spellingShingle |
Biology and Life Sciences Molecular Biology Biochemistry CO2 dietary phosphorus bone mineralization Atlantic salmon skeleton fgf23 TROUT ONCORHYNCHUS-MYKISS DANIO-RERIO OSTARIOPHYSI EARLY SEAWATER PHASE RAINBOW-TROUT CARBON-DIOXIDE VERTEBRAL COLUMN FRESH-WATER NUTRIENT DIGESTIBILITIES OCEAN ACIDIFICATION GROWTH-PERFORMANCE Drábiková, Lucia Fjelldal, Per Gunnar Yousaf, Muhammad Naveed Morken, Thea De Clercq, Adelbert McGurk, Charles Witten, Paul Eckhard Elevated water CO2 can prevent dietary-induced osteomalacia in post-smolt Atlantic salmon (Salmo salar, L.) |
topic_facet |
Biology and Life Sciences Molecular Biology Biochemistry CO2 dietary phosphorus bone mineralization Atlantic salmon skeleton fgf23 TROUT ONCORHYNCHUS-MYKISS DANIO-RERIO OSTARIOPHYSI EARLY SEAWATER PHASE RAINBOW-TROUT CARBON-DIOXIDE VERTEBRAL COLUMN FRESH-WATER NUTRIENT DIGESTIBILITIES OCEAN ACIDIFICATION GROWTH-PERFORMANCE |
description |
Expansion of land-based systems in fish farms elevate the content of metabolic carbon dioxide (CO2) in the water. High CO2 is suggested to increase the bone mineral content in Atlantic salmon (Salmo salar, L.). Conversely, low dietary phosphorus (P) halts bone mineralization. This study examines if high CO2 can counteract reduced bone mineralization imposed by low dietary P intake. Atlantic salmon post-seawater transfer (initial weight 207.03 g) were fed diets containing 6.3 g/kg (0.5P), 9.0 g/kg (1P), or 26.8 g/kg (3P) total P for 13 weeks. Atlantic salmon from all dietary P groups were reared in seawater which was not injected with CO2 and contained a regular CO2 level (5 mg/L) or in seawater with injected CO2 thus raising the level to 20 mg/L. Atlantic salmon were analyzed for blood chemistry, bone mineral content, vertebral centra deformities, mechanical properties, bone matrix alterations, expression of bone mineralization, and P metabolism-related genes. High CO2 and high P reduced Atlantic salmon growth and feed intake. High CO2 increased bone mineralization when dietary P was low. Atlantic salmon fed with a low P diet downregulated the fgf23 expression in bone cells indicating an increased renal phosphate reabsorption. The current results suggest that reduced dietary P could be sufficient to maintain bone mineralization under conditions of elevated CO2. This opens up a possibility for lowering the dietary P content under certain farming conditions. |
format |
Article in Journal/Newspaper |
author |
Drábiková, Lucia Fjelldal, Per Gunnar Yousaf, Muhammad Naveed Morken, Thea De Clercq, Adelbert McGurk, Charles Witten, Paul Eckhard |
author_facet |
Drábiková, Lucia Fjelldal, Per Gunnar Yousaf, Muhammad Naveed Morken, Thea De Clercq, Adelbert McGurk, Charles Witten, Paul Eckhard |
author_sort |
Drábiková, Lucia |
title |
Elevated water CO2 can prevent dietary-induced osteomalacia in post-smolt Atlantic salmon (Salmo salar, L.) |
title_short |
Elevated water CO2 can prevent dietary-induced osteomalacia in post-smolt Atlantic salmon (Salmo salar, L.) |
title_full |
Elevated water CO2 can prevent dietary-induced osteomalacia in post-smolt Atlantic salmon (Salmo salar, L.) |
title_fullStr |
Elevated water CO2 can prevent dietary-induced osteomalacia in post-smolt Atlantic salmon (Salmo salar, L.) |
title_full_unstemmed |
Elevated water CO2 can prevent dietary-induced osteomalacia in post-smolt Atlantic salmon (Salmo salar, L.) |
title_sort |
elevated water co2 can prevent dietary-induced osteomalacia in post-smolt atlantic salmon (salmo salar, l.) |
publishDate |
2023 |
url |
https://biblio.ugent.be/publication/01H035F613V87NFT99VTXWZTX4 http://hdl.handle.net/1854/LU-01H035F613V87NFT99VTXWZTX4 https://doi.org/10.3390/biom13040663 https://biblio.ugent.be/publication/01H035F613V87NFT99VTXWZTX4/file/01H035R3W9J1VRKMJC4EF0XZK2 |
genre |
Atlantic salmon Ocean acidification Salmo salar |
genre_facet |
Atlantic salmon Ocean acidification Salmo salar |
op_source |
BIOMOLECULES ISSN: 2218-273X |
op_relation |
info:eu-repo/grantAgreement/EC/H2020/766347 https://biblio.ugent.be/publication/01H035F613V87NFT99VTXWZTX4 http://hdl.handle.net/1854/LU-01H035F613V87NFT99VTXWZTX4 http://dx.doi.org/10.3390/biom13040663 https://biblio.ugent.be/publication/01H035F613V87NFT99VTXWZTX4/file/01H035R3W9J1VRKMJC4EF0XZK2 |
op_rights |
Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.3390/biom13040663 |
container_title |
Biomolecules |
container_volume |
13 |
container_issue |
4 |
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663 |
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1778522359440867328 |