On chronic fatigue syndrome and nosological categories
Chronic fatigue syndrome (CFS) is a heterogeneous disease which presents with pronounced disabling fatigue, sleep disturbances, and cognitive impairment that negatively affects patients' functional capability. CFS remains a poorly defined entity and its etiology is still in question. CFS is nei...
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ftunivgenova:oai:iris.unige.it:11567/893781 2024-02-11T09:54:49+01:00 On chronic fatigue syndrome and nosological categories Sharif, Kassem Watad, Abdulla Bragazzi, Nicola Luigi Lichtbroun, Michael Martini, Mariano Perricone, Carlo Amital, Howard Shoenfeld, Yehuda Sharif, Kassem Watad, Abdulla Bragazzi, Nicola Luigi Lichtbroun, Michael Martini, Mariano Perricone, Carlo Amital, Howard Shoenfeld, Yehuda 2018 ELETTRONICO http://hdl.handle.net/11567/893781 https://doi.org/10.1007/s10067-018-4009-2 eng eng Springer info:eu-repo/semantics/altIdentifier/pmid/29417255 info:eu-repo/semantics/altIdentifier/wos/WOS:000430711600003 volume:37 (5) firstpage:1161 lastpage:1170 numberofpages:10 journal:CLINICAL RHEUMATOLOGY http://hdl.handle.net/11567/893781 doi:10.1007/s10067-018-4009-2 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85041525211 info:eu-repo/semantics/closedAccess Autoimmune syndrome induced by adjuvants Chronic fatigue syndrome Myalgic encephalomyelitis Postural orthostatic tachycardia syndrome info:eu-repo/semantics/article 2018 ftunivgenova https://doi.org/10.1007/s10067-018-4009-2 2024-01-17T17:53:43Z Chronic fatigue syndrome (CFS) is a heterogeneous disease which presents with pronounced disabling fatigue, sleep disturbances, and cognitive impairment that negatively affects patients' functional capability. CFS remains a poorly defined entity and its etiology is still in question. CFS is neither a novel diagnosis nor a new medical condition. From as early as the eighteenth century, a constellation of perplexing symptoms was observed that resembled symptoms of CFS. Commencing with "febricula" and ending with CFS, many names for the disease were proposed including neurocirculatory asthenia, atypical poliomyelitis, Royal Free disease, effort syndrome, Akureyri disease, Tapanui disease, chronic Epstein-Barr virus syndrome, and myalgic encephalitis. To date, it remains unclear whether CFS has an autoimmune component or is a condition that precedes a full-blown autoimmune disease. Research suggests that CFS may overlap with other diseases including postural orthostatic tachycardia syndrome (POTS), autoimmune syndrome induced by adjuvants (ASIA), and Sjögren's syndrome. Additionally, it has been postulated that the earliest manifestations of some autoimmune diseases can present with vague non-specific symptoms similar to CFS. Sometimes only when exposed to a secondary stimulus (e.g., antigen) which could accelerate the natural course of the disease would an individual develop the classic autoimmune disease. Due to the similarity of symptoms, it has been postulated that CFS could simply be an early manifestation of an autoimmune disease. This paper will provide a historical background review of this disease and a discussion of CFS as an entity overlapping with multiple other conditions. Article in Journal/Newspaper Akureyri Akureyri Akureyri Università degli Studi di Genova: CINECA IRIS Akureyri Clinical Rheumatology 37 5 1161 1170 |
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Università degli Studi di Genova: CINECA IRIS |
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language |
English |
topic |
Autoimmune syndrome induced by adjuvants Chronic fatigue syndrome Myalgic encephalomyelitis Postural orthostatic tachycardia syndrome |
spellingShingle |
Autoimmune syndrome induced by adjuvants Chronic fatigue syndrome Myalgic encephalomyelitis Postural orthostatic tachycardia syndrome Sharif, Kassem Watad, Abdulla Bragazzi, Nicola Luigi Lichtbroun, Michael Martini, Mariano Perricone, Carlo Amital, Howard Shoenfeld, Yehuda On chronic fatigue syndrome and nosological categories |
topic_facet |
Autoimmune syndrome induced by adjuvants Chronic fatigue syndrome Myalgic encephalomyelitis Postural orthostatic tachycardia syndrome |
description |
Chronic fatigue syndrome (CFS) is a heterogeneous disease which presents with pronounced disabling fatigue, sleep disturbances, and cognitive impairment that negatively affects patients' functional capability. CFS remains a poorly defined entity and its etiology is still in question. CFS is neither a novel diagnosis nor a new medical condition. From as early as the eighteenth century, a constellation of perplexing symptoms was observed that resembled symptoms of CFS. Commencing with "febricula" and ending with CFS, many names for the disease were proposed including neurocirculatory asthenia, atypical poliomyelitis, Royal Free disease, effort syndrome, Akureyri disease, Tapanui disease, chronic Epstein-Barr virus syndrome, and myalgic encephalitis. To date, it remains unclear whether CFS has an autoimmune component or is a condition that precedes a full-blown autoimmune disease. Research suggests that CFS may overlap with other diseases including postural orthostatic tachycardia syndrome (POTS), autoimmune syndrome induced by adjuvants (ASIA), and Sjögren's syndrome. Additionally, it has been postulated that the earliest manifestations of some autoimmune diseases can present with vague non-specific symptoms similar to CFS. Sometimes only when exposed to a secondary stimulus (e.g., antigen) which could accelerate the natural course of the disease would an individual develop the classic autoimmune disease. Due to the similarity of symptoms, it has been postulated that CFS could simply be an early manifestation of an autoimmune disease. This paper will provide a historical background review of this disease and a discussion of CFS as an entity overlapping with multiple other conditions. |
author2 |
Sharif, Kassem Watad, Abdulla Bragazzi, Nicola Luigi Lichtbroun, Michael Martini, Mariano Perricone, Carlo Amital, Howard Shoenfeld, Yehuda |
format |
Article in Journal/Newspaper |
author |
Sharif, Kassem Watad, Abdulla Bragazzi, Nicola Luigi Lichtbroun, Michael Martini, Mariano Perricone, Carlo Amital, Howard Shoenfeld, Yehuda |
author_facet |
Sharif, Kassem Watad, Abdulla Bragazzi, Nicola Luigi Lichtbroun, Michael Martini, Mariano Perricone, Carlo Amital, Howard Shoenfeld, Yehuda |
author_sort |
Sharif, Kassem |
title |
On chronic fatigue syndrome and nosological categories |
title_short |
On chronic fatigue syndrome and nosological categories |
title_full |
On chronic fatigue syndrome and nosological categories |
title_fullStr |
On chronic fatigue syndrome and nosological categories |
title_full_unstemmed |
On chronic fatigue syndrome and nosological categories |
title_sort |
on chronic fatigue syndrome and nosological categories |
publisher |
Springer |
publishDate |
2018 |
url |
http://hdl.handle.net/11567/893781 https://doi.org/10.1007/s10067-018-4009-2 |
geographic |
Akureyri |
geographic_facet |
Akureyri |
genre |
Akureyri Akureyri Akureyri |
genre_facet |
Akureyri Akureyri Akureyri |
op_relation |
info:eu-repo/semantics/altIdentifier/pmid/29417255 info:eu-repo/semantics/altIdentifier/wos/WOS:000430711600003 volume:37 (5) firstpage:1161 lastpage:1170 numberofpages:10 journal:CLINICAL RHEUMATOLOGY http://hdl.handle.net/11567/893781 doi:10.1007/s10067-018-4009-2 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85041525211 |
op_rights |
info:eu-repo/semantics/closedAccess |
op_doi |
https://doi.org/10.1007/s10067-018-4009-2 |
container_title |
Clinical Rheumatology |
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37 |
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5 |
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1161 |
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1170 |
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