Nerve conduction velocity in CMT1A: what else can we tell?

• Published in: European Journal of Neurology
• Main Authors: Manganelli F, Pisciotta C, Reilly MM, Tozza S, Schenone A, Fabrizi GM, Cavallaro T, Vita G, Padua L, Gemignani F, Laurà M, Hughes RAC, Solari A, Pareyson D, Santoro L, Nolano M, Iodice R, Grandis M, Cabrini I, Bertolasi L, Mazzeo A, Majorana G, Vitetta F, Scaioli V, Ciano C, Calabrese D, Quattrone A, Blake J.
• Other Authors: Manganelli, F, Pisciotta, C, Reilly, Mm, Tozza, S, Schenone, A, Fabrizi, Gm, Cavallaro, T, Vita, G, Padua, L, Gemignani, F, Laurà, M, Hughes, Rac, Solari, A, Pareyson, D, Santoro, L, Nolano, M, Iodice, R, Grandis, M, Cabrini, I, Bertolasi, L, Mazzeo, A, Majorana, G, Vitetta, F, Scaioli, V, Ciano, C, Calabrese, D, Quattrone, A, Blake, J.
• Format: Article in Journal/Newspaper
• Language: English
• Published: Blackwell Publishing Ltd 2016
• Subjects: Charcot−Marie−Tooth disease; CMT-TRIAAL/CMT-TRAUK; CMT1A; hereditary neuropathie; nerve conduction velocity; Neurology; Neurology (clinical); Charcot; DML
• Online Access: http://hdl.handle.net/11567/851189; https://doi.org/10.1111/ene.13079

Background and purpose: Charcot-Marie-Tooth disease (CMT) type 1A is characterized by uniformly reduced nerve conduction velocity (NCV) that is fully penetrant since the first years of life, remains fairly stable through the life and does not correlate with disability whereas compound muscular actio...