Immunoreactive atrial natriuretic peptide and autoradiographic distribution of atrial natriuretic peptide binding sites in the brain of the antarctic fish, Chionodraco hamatus

The anatomical distribution of atrial natriuretic peptide (ANP)-immunoreactive structures and the autoradiographic localization of ANP binding sites were studied in the brain of the Antarctic fish, Chionodraco hamatus. ANP-containing elements were colocated with ANP binding sites in the dorsal media...

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Published in:Polar Biology
Main Authors: PESTARINO, MARIO, CANDIANI, SIMONA, MASINI, MARIA ANGELA, M. STURLA, A. AUGELLO, D. OLIVERI, VALLARINO, MAURO
Other Authors: Pestarino, Mario, Candiani, Simona, Masini, MARIA ANGELA, M., Sturla, A., Augello, D., Oliveri, Vallarino, Mauro
Format: Article in Journal/Newspaper
Language:English
Published: Springer-Verlag 2000
Subjects:
Online Access:https://hdl.handle.net/11567/265617
https://doi.org/10.1007/s003000000140
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spelling ftunivgenova:oai:iris.unige.it:11567/265617 2024-02-11T09:57:53+01:00 Immunoreactive atrial natriuretic peptide and autoradiographic distribution of atrial natriuretic peptide binding sites in the brain of the antarctic fish, Chionodraco hamatus PESTARINO, MARIO CANDIANI, SIMONA MASINI, MARIA ANGELA M. STURLA A. AUGELLO D. OLIVERI VALLARINO, MAURO Pestarino, Mario Candiani, Simona Masini, MARIA ANGELA M., Sturla A., Augello D., Oliveri Vallarino, Mauro 2000 STAMPA https://hdl.handle.net/11567/265617 https://doi.org/10.1007/s003000000140 eng eng Springer-Verlag country:DEU place:Heidelberg info:eu-repo/semantics/altIdentifier/wos/WOS:000089916500005 volume:23 firstpage:691 lastpage:698 numberofpages:7 journal:POLAR BIOLOGY https://hdl.handle.net/11567/265617 doi:10.1007/s003000000140 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-0033820328 info:eu-repo/semantics/article 2000 ftunivgenova https://doi.org/10.1007/s003000000140 2024-01-24T17:38:05Z The anatomical distribution of atrial natriuretic peptide (ANP)-immunoreactive structures and the autoradiographic localization of ANP binding sites were studied in the brain of the Antarctic fish, Chionodraco hamatus. ANP-containing elements were colocated with ANP binding sites in the dorsal medial and lateral subdivisions of the telencephalon, prethalamic nuclear complex, and in the nucleus of the medial longitudinal fasciculus of the mesencephalon. However, mismatching was observed in other brain regions, particularly at mesencephalic and metencephalic levels. In the pituitary, ANP immunoreactivity occurred only in the pars dis- talis, whereas ANP binding sites were localized in the whole pituitary. In this paper we describe the occurrence of ANP immunoreactivity and ANP binding sites in the brain and pituitary of an Antarctic fish. In particular, in the cerebellum and pituitary of C. hamatus, ANP bind- ing sites are distributed in corresponding brain regions of dipnoans, amphibians and mammals. The immuno- cytochemical and histoautoradiographic data suggest that ANP acts as neuromodulator in the brain of C. hamatus. Moreover, the presence of ANP-like sub- stances in tanycytes lining the diencephalic ventricle suggests a chemosensorial role for such liquor-contact- ing cells and a possible modulatory effect of ANP on the osmoregulation of the cerebrospinal fluid. Article in Journal/Newspaper Antarc* Antarctic Università degli Studi di Genova: CINECA IRIS Antarctic The Antarctic Polar Biology 23 10 691 698
institution Open Polar
collection Università degli Studi di Genova: CINECA IRIS
op_collection_id ftunivgenova
language English
description The anatomical distribution of atrial natriuretic peptide (ANP)-immunoreactive structures and the autoradiographic localization of ANP binding sites were studied in the brain of the Antarctic fish, Chionodraco hamatus. ANP-containing elements were colocated with ANP binding sites in the dorsal medial and lateral subdivisions of the telencephalon, prethalamic nuclear complex, and in the nucleus of the medial longitudinal fasciculus of the mesencephalon. However, mismatching was observed in other brain regions, particularly at mesencephalic and metencephalic levels. In the pituitary, ANP immunoreactivity occurred only in the pars dis- talis, whereas ANP binding sites were localized in the whole pituitary. In this paper we describe the occurrence of ANP immunoreactivity and ANP binding sites in the brain and pituitary of an Antarctic fish. In particular, in the cerebellum and pituitary of C. hamatus, ANP bind- ing sites are distributed in corresponding brain regions of dipnoans, amphibians and mammals. The immuno- cytochemical and histoautoradiographic data suggest that ANP acts as neuromodulator in the brain of C. hamatus. Moreover, the presence of ANP-like sub- stances in tanycytes lining the diencephalic ventricle suggests a chemosensorial role for such liquor-contact- ing cells and a possible modulatory effect of ANP on the osmoregulation of the cerebrospinal fluid.
author2 Pestarino, Mario
Candiani, Simona
Masini, MARIA ANGELA
M., Sturla
A., Augello
D., Oliveri
Vallarino, Mauro
format Article in Journal/Newspaper
author PESTARINO, MARIO
CANDIANI, SIMONA
MASINI, MARIA ANGELA
M. STURLA
A. AUGELLO
D. OLIVERI
VALLARINO, MAURO
spellingShingle PESTARINO, MARIO
CANDIANI, SIMONA
MASINI, MARIA ANGELA
M. STURLA
A. AUGELLO
D. OLIVERI
VALLARINO, MAURO
Immunoreactive atrial natriuretic peptide and autoradiographic distribution of atrial natriuretic peptide binding sites in the brain of the antarctic fish, Chionodraco hamatus
author_facet PESTARINO, MARIO
CANDIANI, SIMONA
MASINI, MARIA ANGELA
M. STURLA
A. AUGELLO
D. OLIVERI
VALLARINO, MAURO
author_sort PESTARINO, MARIO
title Immunoreactive atrial natriuretic peptide and autoradiographic distribution of atrial natriuretic peptide binding sites in the brain of the antarctic fish, Chionodraco hamatus
title_short Immunoreactive atrial natriuretic peptide and autoradiographic distribution of atrial natriuretic peptide binding sites in the brain of the antarctic fish, Chionodraco hamatus
title_full Immunoreactive atrial natriuretic peptide and autoradiographic distribution of atrial natriuretic peptide binding sites in the brain of the antarctic fish, Chionodraco hamatus
title_fullStr Immunoreactive atrial natriuretic peptide and autoradiographic distribution of atrial natriuretic peptide binding sites in the brain of the antarctic fish, Chionodraco hamatus
title_full_unstemmed Immunoreactive atrial natriuretic peptide and autoradiographic distribution of atrial natriuretic peptide binding sites in the brain of the antarctic fish, Chionodraco hamatus
title_sort immunoreactive atrial natriuretic peptide and autoradiographic distribution of atrial natriuretic peptide binding sites in the brain of the antarctic fish, chionodraco hamatus
publisher Springer-Verlag
publishDate 2000
url https://hdl.handle.net/11567/265617
https://doi.org/10.1007/s003000000140
geographic Antarctic
The Antarctic
geographic_facet Antarctic
The Antarctic
genre Antarc*
Antarctic
genre_facet Antarc*
Antarctic
op_relation info:eu-repo/semantics/altIdentifier/wos/WOS:000089916500005
volume:23
firstpage:691
lastpage:698
numberofpages:7
journal:POLAR BIOLOGY
https://hdl.handle.net/11567/265617
doi:10.1007/s003000000140
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-0033820328
op_doi https://doi.org/10.1007/s003000000140
container_title Polar Biology
container_volume 23
container_issue 10
container_start_page 691
op_container_end_page 698
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