The tissue specific transcription factor Pit-1 in the Antarctic fish, Trematomus bernacchii
We have investigated the expression of the tissue-specific transcription factor Pit-1 and the distribution of some adenohypophyseal hormones belonging to the GH/PRL and POMC families in the pituitary of Trematomus bernacchii (Perciformes, Notothenioidei), byimmunocy tochemistry. Pit-1 is a member of...
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2002
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Online Access: | https://hdl.handle.net/11567/257400 https://doi.org/10.1007/s00300-002-0384-9 |
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ftunivgenova:oai:iris.unige.it:11567/257400 2024-04-14T08:02:54+00:00 The tissue specific transcription factor Pit-1 in the Antarctic fish, Trematomus bernacchii CANDIANI, SIMONA D. OLIVERI S. CARBONETTI A. AUGELLO PESTARINO, MARIO Candiani, Simona D., Oliveri S., Carbonetti A., Augello Pestarino, Mario 2002 STAMPA https://hdl.handle.net/11567/257400 https://doi.org/10.1007/s00300-002-0384-9 eng eng Springer Verlag country:DEU place:Heidelberg info:eu-repo/semantics/altIdentifier/wos/WOS:000176777800005 volume:25 firstpage:506 lastpage:511 numberofpages:6 journal:POLAR BIOLOGY https://hdl.handle.net/11567/257400 doi:10.1007/s00300-002-0384-9 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-0036922480 info:eu-repo/semantics/article 2002 ftunivgenova https://doi.org/10.1007/s00300-002-0384-9 2024-03-21T02:24:48Z We have investigated the expression of the tissue-specific transcription factor Pit-1 and the distribution of some adenohypophyseal hormones belonging to the GH/PRL and POMC families in the pituitary of Trematomus bernacchii (Perciformes, Notothenioidei), byimmunocy tochemistry. Pit-1 is a member of the POU protein family, and it is responsible for GH, PRL and TSH cell commitment, differentiation and gene expression in mouse. Our results show coexistence of Pit-1, SL, GH and PRL in the pituitaryof T. bernacchii. Cells containing SL, PRL and GH-like substances are widely distributed in the pituitaryand coexist with Pit-1-like proteins. Moreover, SL is not expressed in the pars intermedia as demonstrated in other teleosts, and the peptides related to the proopiomelanocortin familyare not colocalized with Pit-1, SL, GH and PRL. A few TSH cells are scattered throughout the pituitaryand are not colocalized with Pit-1, SL, GH and PRL cells. We conclude that the pituitarygross morphology has peculiar characteristics and Pit-1 could be involved in the regulation of the GH/PRL/SL cell commitment, differentiation and gene expression in the pituitaryof this Antarctic fish. Article in Journal/Newspaper Antarc* Antarctic Università degli Studi di Genova: CINECA IRIS Antarctic The Antarctic Polar Biology 25 7 506 511 |
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Open Polar |
collection |
Università degli Studi di Genova: CINECA IRIS |
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ftunivgenova |
language |
English |
description |
We have investigated the expression of the tissue-specific transcription factor Pit-1 and the distribution of some adenohypophyseal hormones belonging to the GH/PRL and POMC families in the pituitary of Trematomus bernacchii (Perciformes, Notothenioidei), byimmunocy tochemistry. Pit-1 is a member of the POU protein family, and it is responsible for GH, PRL and TSH cell commitment, differentiation and gene expression in mouse. Our results show coexistence of Pit-1, SL, GH and PRL in the pituitaryof T. bernacchii. Cells containing SL, PRL and GH-like substances are widely distributed in the pituitaryand coexist with Pit-1-like proteins. Moreover, SL is not expressed in the pars intermedia as demonstrated in other teleosts, and the peptides related to the proopiomelanocortin familyare not colocalized with Pit-1, SL, GH and PRL. A few TSH cells are scattered throughout the pituitaryand are not colocalized with Pit-1, SL, GH and PRL cells. We conclude that the pituitarygross morphology has peculiar characteristics and Pit-1 could be involved in the regulation of the GH/PRL/SL cell commitment, differentiation and gene expression in the pituitaryof this Antarctic fish. |
author2 |
Candiani, Simona D., Oliveri S., Carbonetti A., Augello Pestarino, Mario |
format |
Article in Journal/Newspaper |
author |
CANDIANI, SIMONA D. OLIVERI S. CARBONETTI A. AUGELLO PESTARINO, MARIO |
spellingShingle |
CANDIANI, SIMONA D. OLIVERI S. CARBONETTI A. AUGELLO PESTARINO, MARIO The tissue specific transcription factor Pit-1 in the Antarctic fish, Trematomus bernacchii |
author_facet |
CANDIANI, SIMONA D. OLIVERI S. CARBONETTI A. AUGELLO PESTARINO, MARIO |
author_sort |
CANDIANI, SIMONA |
title |
The tissue specific transcription factor Pit-1 in the Antarctic fish, Trematomus bernacchii |
title_short |
The tissue specific transcription factor Pit-1 in the Antarctic fish, Trematomus bernacchii |
title_full |
The tissue specific transcription factor Pit-1 in the Antarctic fish, Trematomus bernacchii |
title_fullStr |
The tissue specific transcription factor Pit-1 in the Antarctic fish, Trematomus bernacchii |
title_full_unstemmed |
The tissue specific transcription factor Pit-1 in the Antarctic fish, Trematomus bernacchii |
title_sort |
tissue specific transcription factor pit-1 in the antarctic fish, trematomus bernacchii |
publisher |
Springer Verlag |
publishDate |
2002 |
url |
https://hdl.handle.net/11567/257400 https://doi.org/10.1007/s00300-002-0384-9 |
geographic |
Antarctic The Antarctic |
geographic_facet |
Antarctic The Antarctic |
genre |
Antarc* Antarctic |
genre_facet |
Antarc* Antarctic |
op_relation |
info:eu-repo/semantics/altIdentifier/wos/WOS:000176777800005 volume:25 firstpage:506 lastpage:511 numberofpages:6 journal:POLAR BIOLOGY https://hdl.handle.net/11567/257400 doi:10.1007/s00300-002-0384-9 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-0036922480 |
op_doi |
https://doi.org/10.1007/s00300-002-0384-9 |
container_title |
Polar Biology |
container_volume |
25 |
container_issue |
7 |
container_start_page |
506 |
op_container_end_page |
511 |
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1796318359955963904 |