Controlled Enzymatic Synthesis of Polyesters Based on a Cellulose–Derived Triol Monomer: A Design of Experiment Approach
Regioselective enzymatic polycondensation of the bio-based cellulose derived polyol, Triol-citro, and dimethyl adipate using Candida antarctica Lipase B (CaLB) was investigated. A Design of Experiment approach with MODDE (R) Pro 13 was used to determine important factors in the branching behavior of...
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WILEY-V C H VERLAG GMBH
2024
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Online Access: | https://hdl.handle.net/11567/1175976 https://doi.org/10.1002/cssc.202301841 |
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ftunivgenova:oai:iris.unige.it:11567/1175976 2024-06-23T07:47:48+00:00 Controlled Enzymatic Synthesis of Polyesters Based on a Cellulose–Derived Triol Monomer: A Design of Experiment Approach Warne, Cicely M. Fadlallah, Sami Allais, Florent Guebitz, Georg M. Pellis, Alessandro Warne, Cicely M. Fadlallah, Sami Allais, Florent Guebitz, Georg M. Pellis, Alessandro 2024 ELETTRONICO https://hdl.handle.net/11567/1175976 https://doi.org/10.1002/cssc.202301841 eng eng WILEY-V C H VERLAG GMBH place:POSTFACH 101161, 69451 WEINHEIM, GERMANY info:eu-repo/semantics/altIdentifier/pmid/38545821 info:eu-repo/semantics/altIdentifier/wos/WOS:001209674700001 firstpage:1 lastpage:9 numberofpages:9 journal:CHEMSUSCHEM https://hdl.handle.net/11567/1175976 doi:10.1002/cssc.202301841 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85191745221 Bio–based Enzyme catalysi Green Chemistry NMR spectroscopy Polyesters info:eu-repo/semantics/article 2024 ftunivgenova https://doi.org/10.1002/cssc.202301841 2024-05-27T23:51:23Z Regioselective enzymatic polycondensation of the bio-based cellulose derived polyol, Triol-citro, and dimethyl adipate using Candida antarctica Lipase B (CaLB) was investigated. A Design of Experiment approach with MODDE (R) Pro 13 was used to determine important factors in the branching behavior of this polymer, and reactant ratio, temperature, reaction time and enzyme wt % were the studied factors. Multifunctional polyesters with pendant hydroxy groups were synthesized and fully characterized using 2D NMR techniques to determine degree of branching. Branching was minimal, with a maximum of 16 % observed, and monomer ratio, temperature and reaction time were all determined to be significant factors. In this work, Mn of up to 13 kDa were achieved, while maintaining degree of branching below 15 %, resulting in a linear polyester with the potential to be further functionalized.Polyesters were enzymatically synthesised from a bio-based triol, and a Design of Experiment approach was used to investigate factors that affect the branching during synthesis of this polymer. image Article in Journal/Newspaper Antarc* Antarctica Università degli Studi di Genova: CINECA IRIS ChemSusChem |
institution |
Open Polar |
collection |
Università degli Studi di Genova: CINECA IRIS |
op_collection_id |
ftunivgenova |
language |
English |
topic |
Bio–based Enzyme catalysi Green Chemistry NMR spectroscopy Polyesters |
spellingShingle |
Bio–based Enzyme catalysi Green Chemistry NMR spectroscopy Polyesters Warne, Cicely M. Fadlallah, Sami Allais, Florent Guebitz, Georg M. Pellis, Alessandro Controlled Enzymatic Synthesis of Polyesters Based on a Cellulose–Derived Triol Monomer: A Design of Experiment Approach |
topic_facet |
Bio–based Enzyme catalysi Green Chemistry NMR spectroscopy Polyesters |
description |
Regioselective enzymatic polycondensation of the bio-based cellulose derived polyol, Triol-citro, and dimethyl adipate using Candida antarctica Lipase B (CaLB) was investigated. A Design of Experiment approach with MODDE (R) Pro 13 was used to determine important factors in the branching behavior of this polymer, and reactant ratio, temperature, reaction time and enzyme wt % were the studied factors. Multifunctional polyesters with pendant hydroxy groups were synthesized and fully characterized using 2D NMR techniques to determine degree of branching. Branching was minimal, with a maximum of 16 % observed, and monomer ratio, temperature and reaction time were all determined to be significant factors. In this work, Mn of up to 13 kDa were achieved, while maintaining degree of branching below 15 %, resulting in a linear polyester with the potential to be further functionalized.Polyesters were enzymatically synthesised from a bio-based triol, and a Design of Experiment approach was used to investigate factors that affect the branching during synthesis of this polymer. image |
author2 |
Warne, Cicely M. Fadlallah, Sami Allais, Florent Guebitz, Georg M. Pellis, Alessandro |
format |
Article in Journal/Newspaper |
author |
Warne, Cicely M. Fadlallah, Sami Allais, Florent Guebitz, Georg M. Pellis, Alessandro |
author_facet |
Warne, Cicely M. Fadlallah, Sami Allais, Florent Guebitz, Georg M. Pellis, Alessandro |
author_sort |
Warne, Cicely M. |
title |
Controlled Enzymatic Synthesis of Polyesters Based on a Cellulose–Derived Triol Monomer: A Design of Experiment Approach |
title_short |
Controlled Enzymatic Synthesis of Polyesters Based on a Cellulose–Derived Triol Monomer: A Design of Experiment Approach |
title_full |
Controlled Enzymatic Synthesis of Polyesters Based on a Cellulose–Derived Triol Monomer: A Design of Experiment Approach |
title_fullStr |
Controlled Enzymatic Synthesis of Polyesters Based on a Cellulose–Derived Triol Monomer: A Design of Experiment Approach |
title_full_unstemmed |
Controlled Enzymatic Synthesis of Polyesters Based on a Cellulose–Derived Triol Monomer: A Design of Experiment Approach |
title_sort |
controlled enzymatic synthesis of polyesters based on a cellulose–derived triol monomer: a design of experiment approach |
publisher |
WILEY-V C H VERLAG GMBH |
publishDate |
2024 |
url |
https://hdl.handle.net/11567/1175976 https://doi.org/10.1002/cssc.202301841 |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_relation |
info:eu-repo/semantics/altIdentifier/pmid/38545821 info:eu-repo/semantics/altIdentifier/wos/WOS:001209674700001 firstpage:1 lastpage:9 numberofpages:9 journal:CHEMSUSCHEM https://hdl.handle.net/11567/1175976 doi:10.1002/cssc.202301841 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85191745221 |
op_doi |
https://doi.org/10.1002/cssc.202301841 |
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ChemSusChem |
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