Genomic analysis of three sponge-associated Arthrobacter Antarctic strains, inhibiting the growth of Burkholderia cepacia complex bacteria by synthesizing volatile organic compounds
In this work we analyzed the ability of three Arthrobacter strains (namely TB23, TB26 and CAL618), which were isolated from the Antarctic sponges Haliclonissa verrucosa and Lyssodendrix nobilis, to specifically inhibit the growth of a panel of 40 Burkholderia cepacia complex strains, representing a...
Published in: | Microbiological Research |
---|---|
Main Authors: | , , , , , , , , , , |
Other Authors: | , , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Urban und Fischer Verlag Jena
2014
|
Subjects: | |
Online Access: | https://hdl.handle.net/11567/1072736 https://doi.org/10.1016/j.micres.2013.09.018 |
id |
ftunivgenova:oai:iris.unige.it:11567/1072736 |
---|---|
record_format |
openpolar |
spelling |
ftunivgenova:oai:iris.unige.it:11567/1072736 2024-04-14T08:04:22+00:00 Genomic analysis of three sponge-associated Arthrobacter Antarctic strains, inhibiting the growth of Burkholderia cepacia complex bacteria by synthesizing volatile organic compounds Orlandini V. Maida I. Fondi M. Perrin E. Papaleo M. C. Bosi E. de Pascale D. Tutino M. L. Michaud L. Lo Giudice A. Fani R. Orlandini, V. Maida, I. Fondi, M. Perrin, E. Papaleo, M. C. Bosi, E. de Pascale, D. Tutino, M. L. Michaud, L. Lo Giudice, A. Fani, R. 2014 ELETTRONICO https://hdl.handle.net/11567/1072736 https://doi.org/10.1016/j.micres.2013.09.018 eng eng Urban und Fischer Verlag Jena place:HACKERBRUCKE 6, 80335 MUNICH, GERMANY info:eu-repo/semantics/altIdentifier/wos/WOS:000336777000015 volume:169 firstpage:593 lastpage:601 numberofpages:9 journal:MICROBIOLOGICAL RESEARCH https://hdl.handle.net/11567/1072736 doi:10.1016/j.micres.2013.09.018 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84899993856 Arthrobacter Burkholderia Cystic fibrosi Pangenome VOCs info:eu-repo/semantics/article 2014 ftunivgenova https://doi.org/10.1016/j.micres.2013.09.018 2024-03-21T02:36:53Z In this work we analyzed the ability of three Arthrobacter strains (namely TB23, TB26 and CAL618), which were isolated from the Antarctic sponges Haliclonissa verrucosa and Lyssodendrix nobilis, to specifically inhibit the growth of a panel of 40 Burkholderia cepacia complex strains, representing a major cause of infections in patients that are affected by Cystic Fibrosis. The inhibitory activity was due to the synthesis of antimicrobial compounds, very likely volatile organic compounds (VOCs), and was partially dependent on the growth media that were used for Antarctic strains growth. The phylogenetic analysis revealed that two of them (i.e. CAL 618 and TB23) were very close and very likely belonged to the same Arthrobacter species, whereas the strain TB26 was placed in a distant branch. The genome of the strains TB26 and CAL618 was also sequenced and compared with that of the strain TB23. The analysis revealed that TB23 and CAL618 shared more genomic properties (GC content, genome size, number of genes) than with TB26. Since the three strains exhibited very similar inhibition pattern vs Bcc strains, it is quite possible that genes involved in the biosynthesis of antimicrobial compounds very likely belong to the core genome. © 2013 Elsevier GmbH. Article in Journal/Newspaper Antarc* Antarctic Università degli Studi di Genova: CINECA IRIS Antarctic The Antarctic Microbiological Research 169 7-8 593 601 |
institution |
Open Polar |
collection |
Università degli Studi di Genova: CINECA IRIS |
op_collection_id |
ftunivgenova |
language |
English |
topic |
Arthrobacter Burkholderia Cystic fibrosi Pangenome VOCs |
spellingShingle |
Arthrobacter Burkholderia Cystic fibrosi Pangenome VOCs Orlandini V. Maida I. Fondi M. Perrin E. Papaleo M. C. Bosi E. de Pascale D. Tutino M. L. Michaud L. Lo Giudice A. Fani R. Genomic analysis of three sponge-associated Arthrobacter Antarctic strains, inhibiting the growth of Burkholderia cepacia complex bacteria by synthesizing volatile organic compounds |
topic_facet |
Arthrobacter Burkholderia Cystic fibrosi Pangenome VOCs |
description |
In this work we analyzed the ability of three Arthrobacter strains (namely TB23, TB26 and CAL618), which were isolated from the Antarctic sponges Haliclonissa verrucosa and Lyssodendrix nobilis, to specifically inhibit the growth of a panel of 40 Burkholderia cepacia complex strains, representing a major cause of infections in patients that are affected by Cystic Fibrosis. The inhibitory activity was due to the synthesis of antimicrobial compounds, very likely volatile organic compounds (VOCs), and was partially dependent on the growth media that were used for Antarctic strains growth. The phylogenetic analysis revealed that two of them (i.e. CAL 618 and TB23) were very close and very likely belonged to the same Arthrobacter species, whereas the strain TB26 was placed in a distant branch. The genome of the strains TB26 and CAL618 was also sequenced and compared with that of the strain TB23. The analysis revealed that TB23 and CAL618 shared more genomic properties (GC content, genome size, number of genes) than with TB26. Since the three strains exhibited very similar inhibition pattern vs Bcc strains, it is quite possible that genes involved in the biosynthesis of antimicrobial compounds very likely belong to the core genome. © 2013 Elsevier GmbH. |
author2 |
Orlandini, V. Maida, I. Fondi, M. Perrin, E. Papaleo, M. C. Bosi, E. de Pascale, D. Tutino, M. L. Michaud, L. Lo Giudice, A. Fani, R. |
format |
Article in Journal/Newspaper |
author |
Orlandini V. Maida I. Fondi M. Perrin E. Papaleo M. C. Bosi E. de Pascale D. Tutino M. L. Michaud L. Lo Giudice A. Fani R. |
author_facet |
Orlandini V. Maida I. Fondi M. Perrin E. Papaleo M. C. Bosi E. de Pascale D. Tutino M. L. Michaud L. Lo Giudice A. Fani R. |
author_sort |
Orlandini V. |
title |
Genomic analysis of three sponge-associated Arthrobacter Antarctic strains, inhibiting the growth of Burkholderia cepacia complex bacteria by synthesizing volatile organic compounds |
title_short |
Genomic analysis of three sponge-associated Arthrobacter Antarctic strains, inhibiting the growth of Burkholderia cepacia complex bacteria by synthesizing volatile organic compounds |
title_full |
Genomic analysis of three sponge-associated Arthrobacter Antarctic strains, inhibiting the growth of Burkholderia cepacia complex bacteria by synthesizing volatile organic compounds |
title_fullStr |
Genomic analysis of three sponge-associated Arthrobacter Antarctic strains, inhibiting the growth of Burkholderia cepacia complex bacteria by synthesizing volatile organic compounds |
title_full_unstemmed |
Genomic analysis of three sponge-associated Arthrobacter Antarctic strains, inhibiting the growth of Burkholderia cepacia complex bacteria by synthesizing volatile organic compounds |
title_sort |
genomic analysis of three sponge-associated arthrobacter antarctic strains, inhibiting the growth of burkholderia cepacia complex bacteria by synthesizing volatile organic compounds |
publisher |
Urban und Fischer Verlag Jena |
publishDate |
2014 |
url |
https://hdl.handle.net/11567/1072736 https://doi.org/10.1016/j.micres.2013.09.018 |
geographic |
Antarctic The Antarctic |
geographic_facet |
Antarctic The Antarctic |
genre |
Antarc* Antarctic |
genre_facet |
Antarc* Antarctic |
op_relation |
info:eu-repo/semantics/altIdentifier/wos/WOS:000336777000015 volume:169 firstpage:593 lastpage:601 numberofpages:9 journal:MICROBIOLOGICAL RESEARCH https://hdl.handle.net/11567/1072736 doi:10.1016/j.micres.2013.09.018 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84899993856 |
op_doi |
https://doi.org/10.1016/j.micres.2013.09.018 |
container_title |
Microbiological Research |
container_volume |
169 |
container_issue |
7-8 |
container_start_page |
593 |
op_container_end_page |
601 |
_version_ |
1796300860252225536 |