Role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases. Consensus report of group 1 of the Joint EFP/ORCA workshop on the boundaries between caries and periodontal disease
BACKGROUND AND AIMS: The scope of this working group was to review (1) ecological interactions at the dental biofilm in health and disease, (2) the role of microbial communities in the pathogenesis of periodontitis and caries, and (3) the innate host response in caries and periodontal diseases. RESU...
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ftunivgeneve:oai:unige.ch:unige:100628 2023-05-15T17:53:54+02:00 Role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases. Consensus report of group 1 of the Joint EFP/ORCA workshop on the boundaries between caries and periodontal disease Sanz, Mariano Beighton, David Curtis, Michael A. Cury, Jaime A. Dige, Irene Dommisch, Henrik Ellwood, Roger Giacaman, Rodrigo A. Herrera, David Herzberg, Mark C. Könönen, Eija Marsh, Philip D. Meyle, Joerg Mira, Alex Molina Herrera, Ana Cristina Mombelli, Andrea Quirynen, Marc Reynolds, Eric C. Shapira, Lior Zaura, Egija 2017 https://archive-ouverte.unige.ch/unige:100628 fre fre info:eu-repo/semantics/altIdentifier/doi/10.1111/jcpe.12682 unige:100628 https://archive-ouverte.unige.ch/unige:100628 info:eu-repo/semantics/restrictedAccess ISSN: 0303-6979 Journal of Clinical Periodontology, Vol. 44 (2017) pp. S5-S11 info:eu-repo/classification/ddc/617.6 *caries *dental biofilm *dysbiosis *innate host responses *microbial interactions *periodontal diseases *symbiosis Text info:eu-repo/semantics/article Article scientifique info:eu-repo/semantics/publishedVersion 2017 ftunivgeneve https://doi.org/10.1111/jcpe.12682 2022-02-08T22:28:32Z BACKGROUND AND AIMS: The scope of this working group was to review (1) ecological interactions at the dental biofilm in health and disease, (2) the role of microbial communities in the pathogenesis of periodontitis and caries, and (3) the innate host response in caries and periodontal diseases. RESULTS AND CONCLUSIONS: A health-associated biofilm includes genera such as Neisseria, Streptococcus, Actinomyces, Veillonella and Granulicatella. Microorganisms associated with both caries and periodontal diseases are metabolically highly specialized and organized as multispecies microbial biofilms. Progression of these diseases involves multiple microbial interactions driven by different stressors. In caries, the exposure of dental biofilms to dietary sugars and their fermentation to organic acids results in increasing proportions of acidogenic and aciduric species. In gingivitis, plaque accumulation at the gingival margin leads to inflammation and increasing proportions of proteolytic and often obligately anaerobic species. The natural mucosal barriers and saliva are the main innate defence mechanisms against soft tissue bacterial invasion. Similarly, enamel and dentin are important hard tissue barriers to the caries process. Given that the present state of knowledge suggests that the aetiologies of caries and periodontal diseases are mutually independent, the elements of innate immunity that appear to contribute to resistance to both are somewhat coincidental. Article in Journal/Newspaper Orca Université de Genève: Archive ouverte UNIGE Journal of Clinical Periodontology 44 S5 S11 |
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Open Polar |
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Université de Genève: Archive ouverte UNIGE |
op_collection_id |
ftunivgeneve |
language |
French |
topic |
info:eu-repo/classification/ddc/617.6 *caries *dental biofilm *dysbiosis *innate host responses *microbial interactions *periodontal diseases *symbiosis |
spellingShingle |
info:eu-repo/classification/ddc/617.6 *caries *dental biofilm *dysbiosis *innate host responses *microbial interactions *periodontal diseases *symbiosis Sanz, Mariano Beighton, David Curtis, Michael A. Cury, Jaime A. Dige, Irene Dommisch, Henrik Ellwood, Roger Giacaman, Rodrigo A. Herrera, David Herzberg, Mark C. Könönen, Eija Marsh, Philip D. Meyle, Joerg Mira, Alex Molina Herrera, Ana Cristina Mombelli, Andrea Quirynen, Marc Reynolds, Eric C. Shapira, Lior Zaura, Egija Role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases. Consensus report of group 1 of the Joint EFP/ORCA workshop on the boundaries between caries and periodontal disease |
topic_facet |
info:eu-repo/classification/ddc/617.6 *caries *dental biofilm *dysbiosis *innate host responses *microbial interactions *periodontal diseases *symbiosis |
description |
BACKGROUND AND AIMS: The scope of this working group was to review (1) ecological interactions at the dental biofilm in health and disease, (2) the role of microbial communities in the pathogenesis of periodontitis and caries, and (3) the innate host response in caries and periodontal diseases. RESULTS AND CONCLUSIONS: A health-associated biofilm includes genera such as Neisseria, Streptococcus, Actinomyces, Veillonella and Granulicatella. Microorganisms associated with both caries and periodontal diseases are metabolically highly specialized and organized as multispecies microbial biofilms. Progression of these diseases involves multiple microbial interactions driven by different stressors. In caries, the exposure of dental biofilms to dietary sugars and their fermentation to organic acids results in increasing proportions of acidogenic and aciduric species. In gingivitis, plaque accumulation at the gingival margin leads to inflammation and increasing proportions of proteolytic and often obligately anaerobic species. The natural mucosal barriers and saliva are the main innate defence mechanisms against soft tissue bacterial invasion. Similarly, enamel and dentin are important hard tissue barriers to the caries process. Given that the present state of knowledge suggests that the aetiologies of caries and periodontal diseases are mutually independent, the elements of innate immunity that appear to contribute to resistance to both are somewhat coincidental. |
format |
Article in Journal/Newspaper |
author |
Sanz, Mariano Beighton, David Curtis, Michael A. Cury, Jaime A. Dige, Irene Dommisch, Henrik Ellwood, Roger Giacaman, Rodrigo A. Herrera, David Herzberg, Mark C. Könönen, Eija Marsh, Philip D. Meyle, Joerg Mira, Alex Molina Herrera, Ana Cristina Mombelli, Andrea Quirynen, Marc Reynolds, Eric C. Shapira, Lior Zaura, Egija |
author_facet |
Sanz, Mariano Beighton, David Curtis, Michael A. Cury, Jaime A. Dige, Irene Dommisch, Henrik Ellwood, Roger Giacaman, Rodrigo A. Herrera, David Herzberg, Mark C. Könönen, Eija Marsh, Philip D. Meyle, Joerg Mira, Alex Molina Herrera, Ana Cristina Mombelli, Andrea Quirynen, Marc Reynolds, Eric C. Shapira, Lior Zaura, Egija |
author_sort |
Sanz, Mariano |
title |
Role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases. Consensus report of group 1 of the Joint EFP/ORCA workshop on the boundaries between caries and periodontal disease |
title_short |
Role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases. Consensus report of group 1 of the Joint EFP/ORCA workshop on the boundaries between caries and periodontal disease |
title_full |
Role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases. Consensus report of group 1 of the Joint EFP/ORCA workshop on the boundaries between caries and periodontal disease |
title_fullStr |
Role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases. Consensus report of group 1 of the Joint EFP/ORCA workshop on the boundaries between caries and periodontal disease |
title_full_unstemmed |
Role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases. Consensus report of group 1 of the Joint EFP/ORCA workshop on the boundaries between caries and periodontal disease |
title_sort |
role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases. consensus report of group 1 of the joint efp/orca workshop on the boundaries between caries and periodontal disease |
publishDate |
2017 |
url |
https://archive-ouverte.unige.ch/unige:100628 |
genre |
Orca |
genre_facet |
Orca |
op_source |
ISSN: 0303-6979 Journal of Clinical Periodontology, Vol. 44 (2017) pp. S5-S11 |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1111/jcpe.12682 unige:100628 https://archive-ouverte.unige.ch/unige:100628 |
op_rights |
info:eu-repo/semantics/restrictedAccess |
op_doi |
https://doi.org/10.1111/jcpe.12682 |
container_title |
Journal of Clinical Periodontology |
container_volume |
44 |
container_start_page |
S5 |
op_container_end_page |
S11 |
_version_ |
1766161616813948928 |