THE OPTIMIZATION OF ENZYMATIC SYNTHESIS FOR LAUROYL-N-METHYL GLUCAMIDE SURFACTANTS
The optimization of enzymatic synthesis for lauroyl-N-methyl glucamide surfactants is studied. The fraction of palm kernel oil namely lauric acid (AL) was amidificationed with N-methyl glucamine (MGL) to produce lauroyl-N-methyl glucamide. Study was carried out by using immobilized lipase from Candi...
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ftunivgadjahmada:oai:jurnal.ugm.ac.id:article/21384 2023-05-15T14:00:38+02:00 THE OPTIMIZATION OF ENZYMATIC SYNTHESIS FOR LAUROYL-N-METHYL GLUCAMIDE SURFACTANTS Masyithah, Zuhrina Sembiring, Seri Bima Alfian, Zul Herawan, Tjahjono 2011-12-20 application/pdf https://jurnal.ugm.ac.id/ijc/article/view/21384 https://doi.org/10.22146/ijc.21384 eng eng Universitas Gadjah Mada https://jurnal.ugm.ac.id/ijc/article/view/21384/14089 https://jurnal.ugm.ac.id/ijc/article/view/21384 doi:10.22146/ijc.21384 Copyright (c) 2011 Indonesian Journal of Chemistry http://creativecommons.org/licenses/by-nc-nd/4.0 CC-BY-NC-ND Indonesian Journal of Chemistry; Vol 11, No 3 (2011); 223-228 2460-1578 1411-9420 amidification lauric acid N-methyl glucamine Response Surface Methodology info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article 2011 ftunivgadjahmada https://doi.org/10.22146/ijc.21384 2022-04-08T12:21:17Z The optimization of enzymatic synthesis for lauroyl-N-methyl glucamide surfactants is studied. The fraction of palm kernel oil namely lauric acid (AL) was amidificationed with N-methyl glucamine (MGL) to produce lauroyl-N-methyl glucamide. Study was carried out by using immobilized lipase from Candida antarctica (Novozyme 435®), and tert-amylalcohol as a solvent. Response Surface Methodology (RSM) based on a five level, three variable design was employed, firstly, for studying the interactive effect of various parameters on the reaction, and secondly, for the optimization. The reaction parameters observed were Novozyme concentration, substrate molar ratio, and temperature. Simultaneously increasing Novozyme concentration, substrate molar ratio, and temperature improves the reaction yield and the effect of temperature is noted more significant. The expected optimum condition was at molar ratio MGL:AL 1:1, the Novozyme concentration of 8% and the reaction temperature of 50-55 °C. The reactions at the optimum condition produce the convertion of lauric acid of 64.5% and yield of 96.5%. With the optimization procedure the higher alkyl glucamide yield was achieved. Article in Journal/Newspaper Antarc* Antarctica Jurnal Online Universitas Gadjah Mada (UGM) Indonesian Journal of Chemistry 11 3 223 228 |
institution |
Open Polar |
collection |
Jurnal Online Universitas Gadjah Mada (UGM) |
op_collection_id |
ftunivgadjahmada |
language |
English |
topic |
amidification lauric acid N-methyl glucamine Response Surface Methodology |
spellingShingle |
amidification lauric acid N-methyl glucamine Response Surface Methodology Masyithah, Zuhrina Sembiring, Seri Bima Alfian, Zul Herawan, Tjahjono THE OPTIMIZATION OF ENZYMATIC SYNTHESIS FOR LAUROYL-N-METHYL GLUCAMIDE SURFACTANTS |
topic_facet |
amidification lauric acid N-methyl glucamine Response Surface Methodology |
description |
The optimization of enzymatic synthesis for lauroyl-N-methyl glucamide surfactants is studied. The fraction of palm kernel oil namely lauric acid (AL) was amidificationed with N-methyl glucamine (MGL) to produce lauroyl-N-methyl glucamide. Study was carried out by using immobilized lipase from Candida antarctica (Novozyme 435®), and tert-amylalcohol as a solvent. Response Surface Methodology (RSM) based on a five level, three variable design was employed, firstly, for studying the interactive effect of various parameters on the reaction, and secondly, for the optimization. The reaction parameters observed were Novozyme concentration, substrate molar ratio, and temperature. Simultaneously increasing Novozyme concentration, substrate molar ratio, and temperature improves the reaction yield and the effect of temperature is noted more significant. The expected optimum condition was at molar ratio MGL:AL 1:1, the Novozyme concentration of 8% and the reaction temperature of 50-55 °C. The reactions at the optimum condition produce the convertion of lauric acid of 64.5% and yield of 96.5%. With the optimization procedure the higher alkyl glucamide yield was achieved. |
format |
Article in Journal/Newspaper |
author |
Masyithah, Zuhrina Sembiring, Seri Bima Alfian, Zul Herawan, Tjahjono |
author_facet |
Masyithah, Zuhrina Sembiring, Seri Bima Alfian, Zul Herawan, Tjahjono |
author_sort |
Masyithah, Zuhrina |
title |
THE OPTIMIZATION OF ENZYMATIC SYNTHESIS FOR LAUROYL-N-METHYL GLUCAMIDE SURFACTANTS |
title_short |
THE OPTIMIZATION OF ENZYMATIC SYNTHESIS FOR LAUROYL-N-METHYL GLUCAMIDE SURFACTANTS |
title_full |
THE OPTIMIZATION OF ENZYMATIC SYNTHESIS FOR LAUROYL-N-METHYL GLUCAMIDE SURFACTANTS |
title_fullStr |
THE OPTIMIZATION OF ENZYMATIC SYNTHESIS FOR LAUROYL-N-METHYL GLUCAMIDE SURFACTANTS |
title_full_unstemmed |
THE OPTIMIZATION OF ENZYMATIC SYNTHESIS FOR LAUROYL-N-METHYL GLUCAMIDE SURFACTANTS |
title_sort |
optimization of enzymatic synthesis for lauroyl-n-methyl glucamide surfactants |
publisher |
Universitas Gadjah Mada |
publishDate |
2011 |
url |
https://jurnal.ugm.ac.id/ijc/article/view/21384 https://doi.org/10.22146/ijc.21384 |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_source |
Indonesian Journal of Chemistry; Vol 11, No 3 (2011); 223-228 2460-1578 1411-9420 |
op_relation |
https://jurnal.ugm.ac.id/ijc/article/view/21384/14089 https://jurnal.ugm.ac.id/ijc/article/view/21384 doi:10.22146/ijc.21384 |
op_rights |
Copyright (c) 2011 Indonesian Journal of Chemistry http://creativecommons.org/licenses/by-nc-nd/4.0 |
op_rightsnorm |
CC-BY-NC-ND |
op_doi |
https://doi.org/10.22146/ijc.21384 |
container_title |
Indonesian Journal of Chemistry |
container_volume |
11 |
container_issue |
3 |
container_start_page |
223 |
op_container_end_page |
228 |
_version_ |
1766269868873613312 |