Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey
The age of onset of rheumatoid arthritis (RA) is an important outcome predictor. Northern countries report an age of RA onset of around 50 years, but apparently, variability exists across different geographical regions. The objective of the present study is to assess whether the age of onset of RA v...
Published in: | Clinical Rheumatology |
---|---|
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Springer London Ltd
2017
|
Subjects: | |
Online Access: | https://repositorio.unifesp.br/handle/11600/55007 https://doi.org/10.1007/s10067-016-3481-9 |
id |
ftunivfsaopaulo:oai:repositorio.unifesp.br:11600/55007 |
---|---|
record_format |
openpolar |
institution |
Open Polar |
collection |
Universidade Federal de São Paulo (UNIFESP): Repositório Institucional |
op_collection_id |
ftunivfsaopaulo |
language |
English |
topic |
Age of onset Environmental Geoepidemiology Inequality Pollution Rheumatoid arthritis |
spellingShingle |
Age of onset Environmental Geoepidemiology Inequality Pollution Rheumatoid arthritis Ramos-Remus, Cesar Barajas-Ochoa, Aldo Ramirez-Gomez, Andrea Castillo-Ortiz, Jose D. Brambila-Barba, Victor Adebajo, Adewale O. Espinoza, Luis R. Aceves-Avila, Francisco J. Sanchez-Gonzalez, Jorge M. Boudersa, Nadia Slimani, Samy Ladjouze-Rezig, Aicha Diaz, Monica P. Kirmayr, Karin I. Asnal, Cecilia A. Catoggio, Luis J. Citera, Gustavo Casado, Gustavo C. Alvarez, Analia P. Pisoni, Cecilia N. Benavente, Emilio Lopez-Cabanillas, Adriana Baez, Roberto M. Pons-Estel, Bernardo A. Sacnun, Monica P. Cavallasca, Javier A. Paniego, Raul H. Proudman, Susanna M. Thomas, Ranjeny Major, Gabor Mathers, David M. Schrieber, Leslie Islam, Nazrul Haq, Syed A. Dessein, Patrick H. von Muhlen, Carlos A. Bianchi, Washington A. Castelar-Pinheiro, Geraldo da R. Feldman-Pollak, Daniel Cossermelli, Waldenise Bonfiglioli, Karina R. Giorgi, Rina D. Zabsonre-Tiendrebeogo, Wendlassida J. Olaru, Lilia Karsh, Jacob Castro-Esparza, Irene H. Fuentealba, Carlos Aguilera, Sergio Burgos, Paula I. Neira, Oscar Li, Zhan-guo Tam, Lai-Shan Mok, Mo Y. Medina, Yimy F. Zuniga-Vera, Andres E. Moreno-Alvarez, Mario J. Vera, Claudia Quezada, Ivonne Moreno, Ivan M. Calapaqui, Wendy El-Mardenly, Ghada Salama, M. Salah Ragab, Gaafar Gado, Kamel Hadidi, Tahsin Leirisalo-Repo, Marjatta Tuompo, Riitta Koivuniemi, Riitta Berenbaum, Francis Allanore, Yannick Constantin, Arnaud Buttgereit, Frank Schulze-Koops, Hendrik Liz, Myriam Dey, Dzifa Santiago-Pastelin, Carlos B. Alonzo-Borjas, Hugo D. Cuellar-Cruz, Victor Dharmanand, Balebail G. Yathish, G. C. Akerkar, Shashank M. Malaviya, Anand N. Ahmadzadeh, Arman Hasunuma, Tomoko Owino, Benard O. Pacheco-Tena, Cesar Frausto-Arenas, Aaron De la Madrid-Cernas, Adrian A. Cardona-Cabrera, Roman Centeno-Valadez, Juan D. Rodriguez-Torres, Isaura M. Vaidya, Binit Gupta, Arun K. Harrison, Andrew A. Grainger, Rebecca Nwankwo, Henry M. Diamantopoulos, Andreas P. Maeland, Elisabeth Besada, Emilio Gorriz, Luis Duarte, Margarita Cabrera-Villalba, Sonia Albrecht, Maria T. Romero-de Garcia-Poma, Augusto Segami, Maria I. Ramos, Maria P. Perez-Medina, Wilkerson Dianongco, Maria L. Lichauco, Juan J. Racaza, Geraldine Z. Navarra, Sandra V. Torralba, Tito P. Manapat-Reyes, Bernadette H. Penserga, Ester G. Hammoudeh, Mohammed Al-Emadi, Samar Botchkova, Anna G. AlSaeedi, Sabri H. Almoallim, Hani Al-Arfaj, Hussein F. Koh, Wei H. Leung, Ying Y. Whitelaw, David A. Hodkinson, Bridget Garcia-Miguel, Javier Duro, Juan C. Martin-Mola, Emilio Ahijon-Lana, Maria Andreu, Jose L. Finckh, Axel Alpizar-Rodriguez, Deshire Osiri, Manathip Kasitanon, Nuntana Louthrenoo, Worawit van Vollenhoven, Ronald F. de Vries, Niek van Denderen, Christiaan Gerritsen, Martjin Jansen, Tim L. van Riel, Piet Nunez-Sotelo, Concepcion M. Villegas-Morales, Sol Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey |
topic_facet |
Age of onset Environmental Geoepidemiology Inequality Pollution Rheumatoid arthritis |
description |
The age of onset of rheumatoid arthritis (RA) is an important outcome predictor. Northern countries report an age of RA onset of around 50 years, but apparently, variability exists across different geographical regions. The objective of the present study is to assess whether the age of onset of RA varies across latitudes worldwide. In a proof-of-concept cross-sectional worldwide survey, rheumatologists from preselected cities interviewed 20 consecutive RA patients regarding the date of RA onset (RAO, when the patient first noted a swollen joint). Other studied variables included location of each city, rheumatologist settings, latitudes (10A degrees increments, south to north), longitudes (three regions), intracountry consistency, and countries' Inequality-adjusted Human Development Index (IHDI). Data from 2481 patients (82% females) were obtained from 126 rheumatologists in 77 cities of 41 countries. Worldwide mean age of RAO was 44 +/- 14 years (95% CI 44-45). In 28% of patients, RA began before age 36 years and before age 46 years in 50% of patients. RAO was 8 years earlier around the Tropic of Cancer when compared with northern latitudes (p < 0.001, 95% CI 3.5-13). Multivariate analysis showed that females, western cities, and latitudes around the Tropic of Cancer are associated with younger age of RAO (R (2) 0.045, p < 0.001). A positive correlation was found between the age of RAO and IHDI (r = 0.7, p < 0.01, R (2) 0.5). RA often begins at an early age and onset varies across latitudes worldwide. We postulate that countries' developmental status and their geographical and geomagnetic location influence the age of RAO. Univ Autonoma Guadalajara, Guadalajara, Jalisco, Mexico Unidad Invest Enfermedades Cronico Degenerat, Guadalajara, Jalisco, Mexico Univ Sheffield, Fac Med Dent & Hlth, Sheffield, S Yorkshire, England LSU Hlth Sci Ctr, New Orleans, LA USA Hosp Gen Reg 46, Inst Mexicano Seguro Social, Guadalajara, Jalisco, Mexico Secretaria Salud Jalisco, Guadalajara, Jalisco, Mexico Dr Benbadis Univ Hosp, Constantine, Algeria Univ Batna 2, Batna, Algeria Univ Algiers, Ben Aknoun Hosp, Algiers, Algeria Ctr Traumatol Bariloche, San Carlos De Bariloche, Rio Negro, Argentina Sanatorio San Carlos, San Carlos De Bariloche, Rio Negro, Argentina Hosp Aleman, Buenos Aires, DF, Argentina Inst Univ, Hosp Italiano Buenos Aires, Escuela Med, Hosp Italiano Buenos Aires, Buenos Aires, DF, Argentina Fundación Dr Pedro M Catoggio Progreso Reumatol, Buenos Aires, DF, Argentina Inst Rehabil Psicofis, Buenos Aires, DF, Argentina Hosp Mil Cent, Buenos Aires, DF, Argentina Hosp Penna, Buenos Aires, DF, Argentina CEMIC, Dept Med Interna, Buenos Aires, DF, Argentina Hosp Distrito Sanitario Eva Peron 8, Formosa, Argentina Ctr Fleboestet Sur, Gen Roca, Argentina Hosp Zonal Gen Roca, Gen Roca, Argentina Inst Cardiovasc Rosario, Rosario, Argentina Hosp Prov Rosario, Rosario, Argentina Hosp JB Iturraspe, Secc Reumatol & Enfermedades Autoimmunes, Santa Fe, Argentina Ctr Privado Rehabil, Santa Rosa, Argentina Univ Adelaide, Royal Adelaide Hosp, Adelaide, SA, Australia Univ Adelaide, Discipline Med, Adelaide, SA, Australia |Univ Queensland, Princess Alexandra Hosp, Diamantina Inst, Brisbane, Qld, Australia Bone & Joint Inst Royal New Castle Ctr, Newcastle, NSW, Australia Univ Newcastle, Newcastle, NSW, Australia Georgetown Arthrit, Newcastle, NSW, Australia Royal North Shore Hosp, Dept Rheumatol, Inst Bone & Joint Res, Kolling Inst, Sydney, NSW, Australia Bangabandhu Sheikh MujibMed Univ, Dept Rheumatol, Dhaka, Bangladesh Univ Hosp Brussels, Div Rheumatol, Brussels, Belgium Free Univ Brussels, Brussels, Belgium Rheuma Clin, Porto Alegre, RS, Brazil Brazilian Soc Autoimmun, Porto Alegre, RS, Brazil Pontificia Univ Catolica Rio de Janeiro, Postgrad Sch, Rio De Janeiro, Brazil Santa Casa da Misericordia Rio de Janeiro Gen Hos, Dept Rheumatol, Rio De Janeiro, Brazil Univ Estado Rio de Janeiro, Rio De Janeiro, Brazil Univ Fed Sao Paulo, Escola Paulista Med, Sao Paulo, Brazil Sch Med Jundiai, Div Rheumatol, Sao Paulo, Brazil Univ Sao Paulo, Fac Med, Hosp Clin, Sao Paulo, Brazil HSPE FMO, Serv Reumatol, Sao Paulo, Brazil Univ Ouagadougou, Ctr Hosp Univ Yalgado Ouedraogo, Ouagadougou, Burkina Faso Univ Alberta, Edmonton, AB, Canada Ottawa Hosp, Ottawa, ON, Canada Univ Concepcion, Concepcion, Chile Hosp Clin San Borja Arriaran, Santiago, Chile Univ Chile, Clin Indisa, Santiago, Chile Pontificia Univ Catolica Chile, Santiago, Chile Univ Chile, Hosp Salvador, Fac Med, Santiago, Chile UDD, Fac Med Clin Alemana, Clin Alemana, Santiago, Chile Beijing Univ, Sch Med, Peoples Hosp, Dept Rheumatol & Immunol, Beijing, Peoples R China Chinese Univ Hong Kong, Dept Med & Therapeut, Hong Kong, Hong Kong, Peoples R China City Univ Hong Kong, Dept Biomed Sci, Hong Kong, Hong Kong, Peoples R China Univ Nacl Colombia, Bogota, Colombia Hosp Luis Vernaza, Guayaquil, Ecuador Univ Catolica Guayaquil, Guayaquil, Ecuador Hosp Especialidades Eugenio Espejo, Quito, Ecuador Clin Santa Lucia, Quito, Ecuador Ctr Atenc Ambulatoria El Batan IESS, Quito, Ecuador Cairo Univ Hosp, Rheumatol Unit, Cairo, Egypt Ain Shams Univ, Dept Med, Cairo, Egypt Cairo Univ, Fac Med, Dept Internal Med, Rheumatol & Immunol Unit, Cairo, Egypt Ctr Rheumatol, Cairo, Egypt Helsinki Univ Hosp, Dept Rheumatol, Helsinki, Finland Univ Helsinki, Helsinki, Finland Kanta Hame Hosp, Riihimaki, Finland Fac Med Pierre & Marie Curie Paris VI, INSERM, UMR S938, Paris, France Hop St Antoine, AP HP, Dept Rheumatol, Paris, France Paris Descartes Univ, Cochin Hosp, Rheumatol Dept A, Paris, France Hop Purpan, Ctr Rhumatol, Toulouse, France Univ Paul Sabatier Toulouse III, Toulouse, France Charite Univ Med Berlin CCM, Dept Rheumatol & Clin Immunol, Berlin, Germany Ludwig Maximilians Univ Munchen, Med Klin & Poliklin 4, Div Rheumatol & Clin Immunol, Munich, Germany Univ Ghana, Sch Med & Dent, Accra, Ghana Inst Hondureno Seguridad Social, Tegucigalpa, Honduras Sakra World Hosp, Inst Rheumatol & Autoimmune Disorders, Bangalore, Karnataka, India PD Hinduja Hosp & Med Res Ctr, Mumbai, Maharashtra, India Mumbai Arthrit Clin, Mumbai, Maharashtra, India ISIC Superspecial Hosp, Dept Rheumatol, New Delhi, India A&R Clin Arthrit & Rheumatism, New Delhi, India Shahid Beheshti Univ Med Sci, Tehran, Iran Cent Clin, Tokyo, Japan Kenyatta Natl Hosp, Nairobi, Kenya Univ Autonoma Chihuahua, Fac Med, Chihuahua, Mexico Clin Hosp ISSSTE, Dept Med, Gomez Palacio, Mexico Univ Colima, Colima, Mexico Ctr Reumatol Queretaro, Queretaro, Mexico Inst Mexicano Seguro Social, Hermosillo, Sonora, Mexico Unidad Enfermedades Reumat & Cron Degenerat, Torreon, Mexico Natl Ctr Rheumat Dis, Kathmandu, Nepal Univ Otago, Dept Med, Wellington, New Zealand Univ Otago, Dept Pathol & Mol Med, Wellington, New Zealand Nnamdi Azikiwe Univ, Teaching Hosp, Nnewi, Nigeria Hosp Rheumat Dis, Dept Rheumatol, Haugesund, Norway UiT Arctic Univ Norway, Kirkenes, Norway Finnmarkssykehuset & Kirkenes, Kirkenes, Norway Hosp Santo Tomas, Panama City, Panama Univ Nacl Asuncion, Hosp Clin, Asuncion, Paraguay Sanatorio Santa Clara, Asuncion, Paraguay Hosp Carlos Alcantara B, Lima, Peru Hosp Nacl Edgardo Rebagliati Martins, EsSalud, Lima, Peru Univ Nacl Mayor de San Marcos, Lima, Peru Dr Pablo O Torre Mem Hosp, Manila, Philippines St Lukes Med Ctr, Manila, Philippines St Lukes Med Ctr BGC, Manila, Philippines Manila Doctors Hosp, Manila, Philippines Univ Philippines, Philippine Gen Hosp, Manila, Philippines Univ Santo Tomas Hosp, Manila, Philippines Hamad Med Corp, Doha, Qatar Privat Out Patients Clin Agat, Egorievsk, Russia King Fahad Cent Hosp, Rheumatol Unit, Dept Med, Jeddah, Saudi Arabia Umm Alqura Univ, Alzaidi Chair Res Rheumat Dis, Mecca, Saudi Arabia Dr Soliman Fakeeh Hosp, Dept Med, Jeddah, Saudi Arabia King Saud Univ, Riyadh, Saudi Arabia Koh Wei Howe Arthrit & Rheumatism Med Clin, Singapore, Singapore Singapore Gen Hosp, Dept Rheumatol & Immunol, Singapore, Singapore Duke NUS Grad Med Sch, Singapore, Singapore Tygerberg Hosp, Bellville, South Africa Univ Stellenbosch, Bellville, South Africa Univ Cape Town, Dept Med, Div Rheumatol, Cape Town, South Africa Hosp Univ Sagrat Cor, Barcelona, Spain Clin Pilar, IDC Salud, Rheumatol Unit, Barcelona, Spain Hosp Univ La Paz, Dept Rheumatol, Madrid, Spain Hosp Cent Def Gomez Ulla, Madrid, Spain Hosp Univ Puerta Hierro, Majadahonda, Spain Univ Hosp Geneva, Geneva, Switzerland Chulalongkorn Univ, Fac Med, Dept Med, Div Rheumatol, Bangkok, Thailand Chiang Mai Univ, Fac Med, Dept Internal Med, Div Rheumatol, Chiang Mai, Thailand Amsterdam Rheumatol & Immunol Ctr ARC, Amsterdam, Netherlands Acad Med Ctr, Dept Clin Immunol & Rheumatol, Amsterdam Rheumatol & Immunol Ctr ARC, Amsterdam, Netherlands Amsterdam Rheumatol & Immunol Ctr ARC, Reade Inst, Amsterdam, Netherlands VieCuri Med Ctr, Venlo, Netherlands Radboud Univ Nijmegen, Med Ctr, Sci Inst Qual Healthcare, Nijmegen, Netherlands Bernhoven, Dept Rheumatol, Uden, Netherlands Univ Ctr Occidental Lisandro Alvarado, Clin Razetti Barquisimeto, Barquisimeto, Venezuela Hosp Vargas Caracas, Serv Reumatol, Caracas, Venezuela Univ Fed Sao Paulo, Escola Paulista Med, Sao Paulo, Brazil Web of Science |
format |
Article in Journal/Newspaper |
author |
Ramos-Remus, Cesar Barajas-Ochoa, Aldo Ramirez-Gomez, Andrea Castillo-Ortiz, Jose D. Brambila-Barba, Victor Adebajo, Adewale O. Espinoza, Luis R. Aceves-Avila, Francisco J. Sanchez-Gonzalez, Jorge M. Boudersa, Nadia Slimani, Samy Ladjouze-Rezig, Aicha Diaz, Monica P. Kirmayr, Karin I. Asnal, Cecilia A. Catoggio, Luis J. Citera, Gustavo Casado, Gustavo C. Alvarez, Analia P. Pisoni, Cecilia N. Benavente, Emilio Lopez-Cabanillas, Adriana Baez, Roberto M. Pons-Estel, Bernardo A. Sacnun, Monica P. Cavallasca, Javier A. Paniego, Raul H. Proudman, Susanna M. Thomas, Ranjeny Major, Gabor Mathers, David M. Schrieber, Leslie Islam, Nazrul Haq, Syed A. Dessein, Patrick H. von Muhlen, Carlos A. Bianchi, Washington A. Castelar-Pinheiro, Geraldo da R. Feldman-Pollak, Daniel Cossermelli, Waldenise Bonfiglioli, Karina R. Giorgi, Rina D. Zabsonre-Tiendrebeogo, Wendlassida J. Olaru, Lilia Karsh, Jacob Castro-Esparza, Irene H. Fuentealba, Carlos Aguilera, Sergio Burgos, Paula I. Neira, Oscar Li, Zhan-guo Tam, Lai-Shan Mok, Mo Y. Medina, Yimy F. Zuniga-Vera, Andres E. Moreno-Alvarez, Mario J. Vera, Claudia Quezada, Ivonne Moreno, Ivan M. Calapaqui, Wendy El-Mardenly, Ghada Salama, M. Salah Ragab, Gaafar Gado, Kamel Hadidi, Tahsin Leirisalo-Repo, Marjatta Tuompo, Riitta Koivuniemi, Riitta Berenbaum, Francis Allanore, Yannick Constantin, Arnaud Buttgereit, Frank Schulze-Koops, Hendrik Liz, Myriam Dey, Dzifa Santiago-Pastelin, Carlos B. Alonzo-Borjas, Hugo D. Cuellar-Cruz, Victor Dharmanand, Balebail G. Yathish, G. C. Akerkar, Shashank M. Malaviya, Anand N. Ahmadzadeh, Arman Hasunuma, Tomoko Owino, Benard O. Pacheco-Tena, Cesar Frausto-Arenas, Aaron De la Madrid-Cernas, Adrian A. Cardona-Cabrera, Roman Centeno-Valadez, Juan D. Rodriguez-Torres, Isaura M. Vaidya, Binit Gupta, Arun K. Harrison, Andrew A. Grainger, Rebecca Nwankwo, Henry M. Diamantopoulos, Andreas P. Maeland, Elisabeth Besada, Emilio Gorriz, Luis Duarte, Margarita Cabrera-Villalba, Sonia Albrecht, Maria T. Romero-de Garcia-Poma, Augusto Segami, Maria I. Ramos, Maria P. Perez-Medina, Wilkerson Dianongco, Maria L. Lichauco, Juan J. Racaza, Geraldine Z. Navarra, Sandra V. Torralba, Tito P. Manapat-Reyes, Bernadette H. Penserga, Ester G. Hammoudeh, Mohammed Al-Emadi, Samar Botchkova, Anna G. AlSaeedi, Sabri H. Almoallim, Hani Al-Arfaj, Hussein F. Koh, Wei H. Leung, Ying Y. Whitelaw, David A. Hodkinson, Bridget Garcia-Miguel, Javier Duro, Juan C. Martin-Mola, Emilio Ahijon-Lana, Maria Andreu, Jose L. Finckh, Axel Alpizar-Rodriguez, Deshire Osiri, Manathip Kasitanon, Nuntana Louthrenoo, Worawit van Vollenhoven, Ronald F. de Vries, Niek van Denderen, Christiaan Gerritsen, Martjin Jansen, Tim L. van Riel, Piet Nunez-Sotelo, Concepcion M. Villegas-Morales, Sol |
author_facet |
Ramos-Remus, Cesar Barajas-Ochoa, Aldo Ramirez-Gomez, Andrea Castillo-Ortiz, Jose D. Brambila-Barba, Victor Adebajo, Adewale O. Espinoza, Luis R. Aceves-Avila, Francisco J. Sanchez-Gonzalez, Jorge M. Boudersa, Nadia Slimani, Samy Ladjouze-Rezig, Aicha Diaz, Monica P. Kirmayr, Karin I. Asnal, Cecilia A. Catoggio, Luis J. Citera, Gustavo Casado, Gustavo C. Alvarez, Analia P. Pisoni, Cecilia N. Benavente, Emilio Lopez-Cabanillas, Adriana Baez, Roberto M. Pons-Estel, Bernardo A. Sacnun, Monica P. Cavallasca, Javier A. Paniego, Raul H. Proudman, Susanna M. Thomas, Ranjeny Major, Gabor Mathers, David M. Schrieber, Leslie Islam, Nazrul Haq, Syed A. Dessein, Patrick H. von Muhlen, Carlos A. Bianchi, Washington A. Castelar-Pinheiro, Geraldo da R. Feldman-Pollak, Daniel Cossermelli, Waldenise Bonfiglioli, Karina R. Giorgi, Rina D. Zabsonre-Tiendrebeogo, Wendlassida J. Olaru, Lilia Karsh, Jacob Castro-Esparza, Irene H. Fuentealba, Carlos Aguilera, Sergio Burgos, Paula I. Neira, Oscar Li, Zhan-guo Tam, Lai-Shan Mok, Mo Y. Medina, Yimy F. Zuniga-Vera, Andres E. Moreno-Alvarez, Mario J. Vera, Claudia Quezada, Ivonne Moreno, Ivan M. Calapaqui, Wendy El-Mardenly, Ghada Salama, M. Salah Ragab, Gaafar Gado, Kamel Hadidi, Tahsin Leirisalo-Repo, Marjatta Tuompo, Riitta Koivuniemi, Riitta Berenbaum, Francis Allanore, Yannick Constantin, Arnaud Buttgereit, Frank Schulze-Koops, Hendrik Liz, Myriam Dey, Dzifa Santiago-Pastelin, Carlos B. Alonzo-Borjas, Hugo D. Cuellar-Cruz, Victor Dharmanand, Balebail G. Yathish, G. C. Akerkar, Shashank M. Malaviya, Anand N. Ahmadzadeh, Arman Hasunuma, Tomoko Owino, Benard O. Pacheco-Tena, Cesar Frausto-Arenas, Aaron De la Madrid-Cernas, Adrian A. Cardona-Cabrera, Roman Centeno-Valadez, Juan D. Rodriguez-Torres, Isaura M. Vaidya, Binit Gupta, Arun K. Harrison, Andrew A. Grainger, Rebecca Nwankwo, Henry M. Diamantopoulos, Andreas P. Maeland, Elisabeth Besada, Emilio Gorriz, Luis Duarte, Margarita Cabrera-Villalba, Sonia Albrecht, Maria T. Romero-de Garcia-Poma, Augusto Segami, Maria I. Ramos, Maria P. Perez-Medina, Wilkerson Dianongco, Maria L. Lichauco, Juan J. Racaza, Geraldine Z. Navarra, Sandra V. Torralba, Tito P. Manapat-Reyes, Bernadette H. Penserga, Ester G. Hammoudeh, Mohammed Al-Emadi, Samar Botchkova, Anna G. AlSaeedi, Sabri H. Almoallim, Hani Al-Arfaj, Hussein F. Koh, Wei H. Leung, Ying Y. Whitelaw, David A. Hodkinson, Bridget Garcia-Miguel, Javier Duro, Juan C. Martin-Mola, Emilio Ahijon-Lana, Maria Andreu, Jose L. Finckh, Axel Alpizar-Rodriguez, Deshire Osiri, Manathip Kasitanon, Nuntana Louthrenoo, Worawit van Vollenhoven, Ronald F. de Vries, Niek van Denderen, Christiaan Gerritsen, Martjin Jansen, Tim L. van Riel, Piet Nunez-Sotelo, Concepcion M. Villegas-Morales, Sol |
author_sort |
Ramos-Remus, Cesar |
title |
Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey |
title_short |
Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey |
title_full |
Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey |
title_fullStr |
Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey |
title_full_unstemmed |
Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey |
title_sort |
latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey |
publisher |
Springer London Ltd |
publishDate |
2017 |
url |
https://repositorio.unifesp.br/handle/11600/55007 https://doi.org/10.1007/s10067-016-3481-9 |
op_coverage |
London |
long_lat |
ENVELOPE(142.349,142.349,60.099,60.099) ENVELOPE(-60.800,-60.800,-62.450,-62.450) ENVELOPE(-45.633,-45.633,-60.600,-60.600) ENVELOPE(162.650,162.650,-77.967,-77.967) ENVELOPE(140.050,140.050,-66.649,-66.649) ENVELOPE(141.478,141.478,-66.779,-66.779) ENVELOPE(-64.517,-64.517,-64.833,-64.833) ENVELOPE(-58.795,-58.795,-62.196,-62.196) ENVELOPE(-59.767,-59.767,-62.449,-62.449) ENVELOPE(148.483,148.483,61.350,61.350) ENVELOPE(-61.833,-61.833,-64.500,-64.500) ENVELOPE(-60.667,-60.667,-63.950,-63.950) ENVELOPE(-63.717,-63.717,-64.283,-64.283) ENVELOPE(-59.783,-59.783,-62.450,-62.450) ENVELOPE(-44.817,-44.817,-60.733,-60.733) ENVELOPE(-67.967,-67.967,-67.450,-67.450) ENVELOPE(-59.729,-59.729,-62.413,-62.413) ENVELOPE(6.192,6.192,62.679,62.679) |
geographic |
Agat’ Alvarado Arctic Argentina Brisbane Canada Chiang Dent Descartes Edgardo Gomez Guayaquil Klin Marcos New Zealand Norway Orleans Pablo Queensland Quito Roca Rosario Sheffield Torre Ulla |
geographic_facet |
Agat’ Alvarado Arctic Argentina Brisbane Canada Chiang Dent Descartes Edgardo Gomez Guayaquil Klin Marcos New Zealand Norway Orleans Pablo Queensland Quito Roca Rosario Sheffield Torre Ulla |
genre |
Arctic Kirkenes |
genre_facet |
Arctic Kirkenes |
op_relation |
Clinical Rheumatology http://dx.doi.org/10.1007/s10067-016-3481-9 Clinical Rheumatology. London, v. 36, n. 3, p. 485-497, 2017. 0770-3198 https://repositorio.unifesp.br/handle/11600/55007 doi:10.1007/s10067-016-3481-9 WOS:000394989700001 |
op_rights |
Acesso restrito |
op_doi |
https://doi.org/10.1007/s10067-016-3481-9 |
container_title |
Clinical Rheumatology |
container_volume |
36 |
container_issue |
3 |
container_start_page |
485 |
op_container_end_page |
497 |
_version_ |
1766351296221151232 |
spelling |
ftunivfsaopaulo:oai:repositorio.unifesp.br:11600/55007 2023-05-15T15:20:58+02:00 Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey Ramos-Remus, Cesar Barajas-Ochoa, Aldo Ramirez-Gomez, Andrea Castillo-Ortiz, Jose D. Brambila-Barba, Victor Adebajo, Adewale O. Espinoza, Luis R. Aceves-Avila, Francisco J. Sanchez-Gonzalez, Jorge M. Boudersa, Nadia Slimani, Samy Ladjouze-Rezig, Aicha Diaz, Monica P. Kirmayr, Karin I. Asnal, Cecilia A. Catoggio, Luis J. Citera, Gustavo Casado, Gustavo C. Alvarez, Analia P. Pisoni, Cecilia N. Benavente, Emilio Lopez-Cabanillas, Adriana Baez, Roberto M. Pons-Estel, Bernardo A. Sacnun, Monica P. Cavallasca, Javier A. Paniego, Raul H. Proudman, Susanna M. Thomas, Ranjeny Major, Gabor Mathers, David M. Schrieber, Leslie Islam, Nazrul Haq, Syed A. Dessein, Patrick H. von Muhlen, Carlos A. Bianchi, Washington A. Castelar-Pinheiro, Geraldo da R. Feldman-Pollak, Daniel Cossermelli, Waldenise Bonfiglioli, Karina R. Giorgi, Rina D. Zabsonre-Tiendrebeogo, Wendlassida J. Olaru, Lilia Karsh, Jacob Castro-Esparza, Irene H. Fuentealba, Carlos Aguilera, Sergio Burgos, Paula I. Neira, Oscar Li, Zhan-guo Tam, Lai-Shan Mok, Mo Y. Medina, Yimy F. Zuniga-Vera, Andres E. Moreno-Alvarez, Mario J. Vera, Claudia Quezada, Ivonne Moreno, Ivan M. Calapaqui, Wendy El-Mardenly, Ghada Salama, M. Salah Ragab, Gaafar Gado, Kamel Hadidi, Tahsin Leirisalo-Repo, Marjatta Tuompo, Riitta Koivuniemi, Riitta Berenbaum, Francis Allanore, Yannick Constantin, Arnaud Buttgereit, Frank Schulze-Koops, Hendrik Liz, Myriam Dey, Dzifa Santiago-Pastelin, Carlos B. Alonzo-Borjas, Hugo D. Cuellar-Cruz, Victor Dharmanand, Balebail G. Yathish, G. C. Akerkar, Shashank M. Malaviya, Anand N. Ahmadzadeh, Arman Hasunuma, Tomoko Owino, Benard O. Pacheco-Tena, Cesar Frausto-Arenas, Aaron De la Madrid-Cernas, Adrian A. Cardona-Cabrera, Roman Centeno-Valadez, Juan D. Rodriguez-Torres, Isaura M. Vaidya, Binit Gupta, Arun K. Harrison, Andrew A. Grainger, Rebecca Nwankwo, Henry M. Diamantopoulos, Andreas P. Maeland, Elisabeth Besada, Emilio Gorriz, Luis Duarte, Margarita Cabrera-Villalba, Sonia Albrecht, Maria T. Romero-de Garcia-Poma, Augusto Segami, Maria I. Ramos, Maria P. Perez-Medina, Wilkerson Dianongco, Maria L. Lichauco, Juan J. Racaza, Geraldine Z. Navarra, Sandra V. Torralba, Tito P. Manapat-Reyes, Bernadette H. Penserga, Ester G. Hammoudeh, Mohammed Al-Emadi, Samar Botchkova, Anna G. AlSaeedi, Sabri H. Almoallim, Hani Al-Arfaj, Hussein F. Koh, Wei H. Leung, Ying Y. Whitelaw, David A. Hodkinson, Bridget Garcia-Miguel, Javier Duro, Juan C. Martin-Mola, Emilio Ahijon-Lana, Maria Andreu, Jose L. Finckh, Axel Alpizar-Rodriguez, Deshire Osiri, Manathip Kasitanon, Nuntana Louthrenoo, Worawit van Vollenhoven, Ronald F. de Vries, Niek van Denderen, Christiaan Gerritsen, Martjin Jansen, Tim L. van Riel, Piet Nunez-Sotelo, Concepcion M. Villegas-Morales, Sol London 2017 485-497 https://repositorio.unifesp.br/handle/11600/55007 https://doi.org/10.1007/s10067-016-3481-9 eng eng Springer London Ltd Clinical Rheumatology http://dx.doi.org/10.1007/s10067-016-3481-9 Clinical Rheumatology. London, v. 36, n. 3, p. 485-497, 2017. 0770-3198 https://repositorio.unifesp.br/handle/11600/55007 doi:10.1007/s10067-016-3481-9 WOS:000394989700001 Acesso restrito Age of onset Environmental Geoepidemiology Inequality Pollution Rheumatoid arthritis Artigo 2017 ftunivfsaopaulo https://doi.org/10.1007/s10067-016-3481-9 2020-12-09T07:48:49Z The age of onset of rheumatoid arthritis (RA) is an important outcome predictor. Northern countries report an age of RA onset of around 50 years, but apparently, variability exists across different geographical regions. The objective of the present study is to assess whether the age of onset of RA varies across latitudes worldwide. In a proof-of-concept cross-sectional worldwide survey, rheumatologists from preselected cities interviewed 20 consecutive RA patients regarding the date of RA onset (RAO, when the patient first noted a swollen joint). Other studied variables included location of each city, rheumatologist settings, latitudes (10A degrees increments, south to north), longitudes (three regions), intracountry consistency, and countries' Inequality-adjusted Human Development Index (IHDI). Data from 2481 patients (82% females) were obtained from 126 rheumatologists in 77 cities of 41 countries. Worldwide mean age of RAO was 44 +/- 14 years (95% CI 44-45). In 28% of patients, RA began before age 36 years and before age 46 years in 50% of patients. RAO was 8 years earlier around the Tropic of Cancer when compared with northern latitudes (p < 0.001, 95% CI 3.5-13). Multivariate analysis showed that females, western cities, and latitudes around the Tropic of Cancer are associated with younger age of RAO (R (2) 0.045, p < 0.001). A positive correlation was found between the age of RAO and IHDI (r = 0.7, p < 0.01, R (2) 0.5). RA often begins at an early age and onset varies across latitudes worldwide. We postulate that countries' developmental status and their geographical and geomagnetic location influence the age of RAO. Univ Autonoma Guadalajara, Guadalajara, Jalisco, Mexico Unidad Invest Enfermedades Cronico Degenerat, Guadalajara, Jalisco, Mexico Univ Sheffield, Fac Med Dent & Hlth, Sheffield, S Yorkshire, England LSU Hlth Sci Ctr, New Orleans, LA USA Hosp Gen Reg 46, Inst Mexicano Seguro Social, Guadalajara, Jalisco, Mexico Secretaria Salud Jalisco, Guadalajara, Jalisco, Mexico Dr Benbadis Univ Hosp, Constantine, Algeria Univ Batna 2, Batna, Algeria Univ Algiers, Ben Aknoun Hosp, Algiers, Algeria Ctr Traumatol Bariloche, San Carlos De Bariloche, Rio Negro, Argentina Sanatorio San Carlos, San Carlos De Bariloche, Rio Negro, Argentina Hosp Aleman, Buenos Aires, DF, Argentina Inst Univ, Hosp Italiano Buenos Aires, Escuela Med, Hosp Italiano Buenos Aires, Buenos Aires, DF, Argentina Fundación Dr Pedro M Catoggio Progreso Reumatol, Buenos Aires, DF, Argentina Inst Rehabil Psicofis, Buenos Aires, DF, Argentina Hosp Mil Cent, Buenos Aires, DF, Argentina Hosp Penna, Buenos Aires, DF, Argentina CEMIC, Dept Med Interna, Buenos Aires, DF, Argentina Hosp Distrito Sanitario Eva Peron 8, Formosa, Argentina Ctr Fleboestet Sur, Gen Roca, Argentina Hosp Zonal Gen Roca, Gen Roca, Argentina Inst Cardiovasc Rosario, Rosario, Argentina Hosp Prov Rosario, Rosario, Argentina Hosp JB Iturraspe, Secc Reumatol & Enfermedades Autoimmunes, Santa Fe, Argentina Ctr Privado Rehabil, Santa Rosa, Argentina Univ Adelaide, Royal Adelaide Hosp, Adelaide, SA, Australia Univ Adelaide, Discipline Med, Adelaide, SA, Australia |Univ Queensland, Princess Alexandra Hosp, Diamantina Inst, Brisbane, Qld, Australia Bone & Joint Inst Royal New Castle Ctr, Newcastle, NSW, Australia Univ Newcastle, Newcastle, NSW, Australia Georgetown Arthrit, Newcastle, NSW, Australia Royal North Shore Hosp, Dept Rheumatol, Inst Bone & Joint Res, Kolling Inst, Sydney, NSW, Australia Bangabandhu Sheikh MujibMed Univ, Dept Rheumatol, Dhaka, Bangladesh Univ Hosp Brussels, Div Rheumatol, Brussels, Belgium Free Univ Brussels, Brussels, Belgium Rheuma Clin, Porto Alegre, RS, Brazil Brazilian Soc Autoimmun, Porto Alegre, RS, Brazil Pontificia Univ Catolica Rio de Janeiro, Postgrad Sch, Rio De Janeiro, Brazil Santa Casa da Misericordia Rio de Janeiro Gen Hos, Dept Rheumatol, Rio De Janeiro, Brazil Univ Estado Rio de Janeiro, Rio De Janeiro, Brazil Univ Fed Sao Paulo, Escola Paulista Med, Sao Paulo, Brazil Sch Med Jundiai, Div Rheumatol, Sao Paulo, Brazil Univ Sao Paulo, Fac Med, Hosp Clin, Sao Paulo, Brazil HSPE FMO, Serv Reumatol, Sao Paulo, Brazil Univ Ouagadougou, Ctr Hosp Univ Yalgado Ouedraogo, Ouagadougou, Burkina Faso Univ Alberta, Edmonton, AB, Canada Ottawa Hosp, Ottawa, ON, Canada Univ Concepcion, Concepcion, Chile Hosp Clin San Borja Arriaran, Santiago, Chile Univ Chile, Clin Indisa, Santiago, Chile Pontificia Univ Catolica Chile, Santiago, Chile Univ Chile, Hosp Salvador, Fac Med, Santiago, Chile UDD, Fac Med Clin Alemana, Clin Alemana, Santiago, Chile Beijing Univ, Sch Med, Peoples Hosp, Dept Rheumatol & Immunol, Beijing, Peoples R China Chinese Univ Hong Kong, Dept Med & Therapeut, Hong Kong, Hong Kong, Peoples R China City Univ Hong Kong, Dept Biomed Sci, Hong Kong, Hong Kong, Peoples R China Univ Nacl Colombia, Bogota, Colombia Hosp Luis Vernaza, Guayaquil, Ecuador Univ Catolica Guayaquil, Guayaquil, Ecuador Hosp Especialidades Eugenio Espejo, Quito, Ecuador Clin Santa Lucia, Quito, Ecuador Ctr Atenc Ambulatoria El Batan IESS, Quito, Ecuador Cairo Univ Hosp, Rheumatol Unit, Cairo, Egypt Ain Shams Univ, Dept Med, Cairo, Egypt Cairo Univ, Fac Med, Dept Internal Med, Rheumatol & Immunol Unit, Cairo, Egypt Ctr Rheumatol, Cairo, Egypt Helsinki Univ Hosp, Dept Rheumatol, Helsinki, Finland Univ Helsinki, Helsinki, Finland Kanta Hame Hosp, Riihimaki, Finland Fac Med Pierre & Marie Curie Paris VI, INSERM, UMR S938, Paris, France Hop St Antoine, AP HP, Dept Rheumatol, Paris, France Paris Descartes Univ, Cochin Hosp, Rheumatol Dept A, Paris, France Hop Purpan, Ctr Rhumatol, Toulouse, France Univ Paul Sabatier Toulouse III, Toulouse, France Charite Univ Med Berlin CCM, Dept Rheumatol & Clin Immunol, Berlin, Germany Ludwig Maximilians Univ Munchen, Med Klin & Poliklin 4, Div Rheumatol & Clin Immunol, Munich, Germany Univ Ghana, Sch Med & Dent, Accra, Ghana Inst Hondureno Seguridad Social, Tegucigalpa, Honduras Sakra World Hosp, Inst Rheumatol & Autoimmune Disorders, Bangalore, Karnataka, India PD Hinduja Hosp & Med Res Ctr, Mumbai, Maharashtra, India Mumbai Arthrit Clin, Mumbai, Maharashtra, India ISIC Superspecial Hosp, Dept Rheumatol, New Delhi, India A&R Clin Arthrit & Rheumatism, New Delhi, India Shahid Beheshti Univ Med Sci, Tehran, Iran Cent Clin, Tokyo, Japan Kenyatta Natl Hosp, Nairobi, Kenya Univ Autonoma Chihuahua, Fac Med, Chihuahua, Mexico Clin Hosp ISSSTE, Dept Med, Gomez Palacio, Mexico Univ Colima, Colima, Mexico Ctr Reumatol Queretaro, Queretaro, Mexico Inst Mexicano Seguro Social, Hermosillo, Sonora, Mexico Unidad Enfermedades Reumat & Cron Degenerat, Torreon, Mexico Natl Ctr Rheumat Dis, Kathmandu, Nepal Univ Otago, Dept Med, Wellington, New Zealand Univ Otago, Dept Pathol & Mol Med, Wellington, New Zealand Nnamdi Azikiwe Univ, Teaching Hosp, Nnewi, Nigeria Hosp Rheumat Dis, Dept Rheumatol, Haugesund, Norway UiT Arctic Univ Norway, Kirkenes, Norway Finnmarkssykehuset & Kirkenes, Kirkenes, Norway Hosp Santo Tomas, Panama City, Panama Univ Nacl Asuncion, Hosp Clin, Asuncion, Paraguay Sanatorio Santa Clara, Asuncion, Paraguay Hosp Carlos Alcantara B, Lima, Peru Hosp Nacl Edgardo Rebagliati Martins, EsSalud, Lima, Peru Univ Nacl Mayor de San Marcos, Lima, Peru Dr Pablo O Torre Mem Hosp, Manila, Philippines St Lukes Med Ctr, Manila, Philippines St Lukes Med Ctr BGC, Manila, Philippines Manila Doctors Hosp, Manila, Philippines Univ Philippines, Philippine Gen Hosp, Manila, Philippines Univ Santo Tomas Hosp, Manila, Philippines Hamad Med Corp, Doha, Qatar Privat Out Patients Clin Agat, Egorievsk, Russia King Fahad Cent Hosp, Rheumatol Unit, Dept Med, Jeddah, Saudi Arabia Umm Alqura Univ, Alzaidi Chair Res Rheumat Dis, Mecca, Saudi Arabia Dr Soliman Fakeeh Hosp, Dept Med, Jeddah, Saudi Arabia King Saud Univ, Riyadh, Saudi Arabia Koh Wei Howe Arthrit & Rheumatism Med Clin, Singapore, Singapore Singapore Gen Hosp, Dept Rheumatol & Immunol, Singapore, Singapore Duke NUS Grad Med Sch, Singapore, Singapore Tygerberg Hosp, Bellville, South Africa Univ Stellenbosch, Bellville, South Africa Univ Cape Town, Dept Med, Div Rheumatol, Cape Town, South Africa Hosp Univ Sagrat Cor, Barcelona, Spain Clin Pilar, IDC Salud, Rheumatol Unit, Barcelona, Spain Hosp Univ La Paz, Dept Rheumatol, Madrid, Spain Hosp Cent Def Gomez Ulla, Madrid, Spain Hosp Univ Puerta Hierro, Majadahonda, Spain Univ Hosp Geneva, Geneva, Switzerland Chulalongkorn Univ, Fac Med, Dept Med, Div Rheumatol, Bangkok, Thailand Chiang Mai Univ, Fac Med, Dept Internal Med, Div Rheumatol, Chiang Mai, Thailand Amsterdam Rheumatol & Immunol Ctr ARC, Amsterdam, Netherlands Acad Med Ctr, Dept Clin Immunol & Rheumatol, Amsterdam Rheumatol & Immunol Ctr ARC, Amsterdam, Netherlands Amsterdam Rheumatol & Immunol Ctr ARC, Reade Inst, Amsterdam, Netherlands VieCuri Med Ctr, Venlo, Netherlands Radboud Univ Nijmegen, Med Ctr, Sci Inst Qual Healthcare, Nijmegen, Netherlands Bernhoven, Dept Rheumatol, Uden, Netherlands Univ Ctr Occidental Lisandro Alvarado, Clin Razetti Barquisimeto, Barquisimeto, Venezuela Hosp Vargas Caracas, Serv Reumatol, Caracas, Venezuela Univ Fed Sao Paulo, Escola Paulista Med, Sao Paulo, Brazil Web of Science Article in Journal/Newspaper Arctic Kirkenes Universidade Federal de São Paulo (UNIFESP): Repositório Institucional Agat’ ENVELOPE(142.349,142.349,60.099,60.099) Alvarado ENVELOPE(-60.800,-60.800,-62.450,-62.450) Arctic Argentina Brisbane ENVELOPE(-45.633,-45.633,-60.600,-60.600) Canada Chiang ENVELOPE(162.650,162.650,-77.967,-77.967) Dent ENVELOPE(140.050,140.050,-66.649,-66.649) Descartes ENVELOPE(141.478,141.478,-66.779,-66.779) Edgardo ENVELOPE(-64.517,-64.517,-64.833,-64.833) Gomez ENVELOPE(-58.795,-58.795,-62.196,-62.196) Guayaquil ENVELOPE(-59.767,-59.767,-62.449,-62.449) Klin ENVELOPE(148.483,148.483,61.350,61.350) Marcos ENVELOPE(-61.833,-61.833,-64.500,-64.500) New Zealand Norway Orleans ENVELOPE(-60.667,-60.667,-63.950,-63.950) Pablo ENVELOPE(-63.717,-63.717,-64.283,-64.283) Queensland Quito ENVELOPE(-59.783,-59.783,-62.450,-62.450) Roca ENVELOPE(-44.817,-44.817,-60.733,-60.733) Rosario ENVELOPE(-67.967,-67.967,-67.450,-67.450) Sheffield Torre ENVELOPE(-59.729,-59.729,-62.413,-62.413) Ulla ENVELOPE(6.192,6.192,62.679,62.679) Clinical Rheumatology 36 3 485 497 |