Genetic variation and population structure in native americans
We examined genetic diversity and population structure in the American landmass using 678 autosomal microsatellite markers genotyped in 422 individuals representing 24 Native American populations sampled from North, Central, and South America. These data were analyzed jointly with similar data avail...
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ftunivfrgs:oai:lume.ufrgs.br:10183/21545 2023-05-15T15:44:14+02:00 Genetic variation and population structure in native americans Wang, Sijia Lewis Junior, Cecil M. Jakobsson, Mattias Ramachandran, Sohini Ray, Nicolas Bedoya, Gabriel Rojas, Winston Parra, María V. Molina, Julio A. Gallo, Carla Mazzotti, Guido Poletti, Giovanni Hill, Kim R. Hurtado, Ana Magdalena Labuda, Damian Klitz, William Barrantes, Ramiro Bortolini, Maria Cátira Salzano, Francisco Mauro Petzl-Erler, Maria Luiza Tsuneto, Luiza T. Llop, Elena Rothhammer, Francisco Excoffier, Laurent Feldman, Marcus W. Rosenberg, Noah A. Ruiz-Linares, Andres 2008 application/pdf http://hdl.handle.net/10183/21545 eng eng Plos Genetics. Cambridge. Vol. 3, n. 11 (Nov. 2007), p. 2049-2067 Open Access Genética humana Variacao genetica América Artigo de periódico Estrangeiro 2008 ftunivfrgs 2018-10-06T23:11:50Z We examined genetic diversity and population structure in the American landmass using 678 autosomal microsatellite markers genotyped in 422 individuals representing 24 Native American populations sampled from North, Central, and South America. These data were analyzed jointly with similar data available in 54 other indigenous populations worldwide, including an additional five Native American groups. The Native American populations have lower genetic diversity and greater differentiation than populations from other continental regions. We observe gradients both of decreasing genetic diversity as a function of geographic distance from the Bering Strait and of decreasing genetic similarity to Siberians—signals of the southward dispersal of human populations from the northwestern tip of the Americas. We also observe evidence of: (1) a higher level of diversity and lower level of population structure in western South America compared to eastern South America, (2) a relative lack of differentiation between Mesoamerican and Andean populations, (3) a scenario in which coastal routes were easier for migrating peoples to traverse in comparison with inland routes, and (4) a partial agreement on a local scale between genetic similarity and the linguistic classification of populations. These findings offer new insights into the process of population dispersal and differentiation during the peopling of the Americas. Article in Journal/Newspaper Bering Strait Universidade Federal do Rio Grande do Sul (UFRGS): Lume Bering Strait |
institution |
Open Polar |
collection |
Universidade Federal do Rio Grande do Sul (UFRGS): Lume |
op_collection_id |
ftunivfrgs |
language |
English |
topic |
Genética humana Variacao genetica América |
spellingShingle |
Genética humana Variacao genetica América Wang, Sijia Lewis Junior, Cecil M. Jakobsson, Mattias Ramachandran, Sohini Ray, Nicolas Bedoya, Gabriel Rojas, Winston Parra, María V. Molina, Julio A. Gallo, Carla Mazzotti, Guido Poletti, Giovanni Hill, Kim R. Hurtado, Ana Magdalena Labuda, Damian Klitz, William Barrantes, Ramiro Bortolini, Maria Cátira Salzano, Francisco Mauro Petzl-Erler, Maria Luiza Tsuneto, Luiza T. Llop, Elena Rothhammer, Francisco Excoffier, Laurent Feldman, Marcus W. Rosenberg, Noah A. Ruiz-Linares, Andres Genetic variation and population structure in native americans |
topic_facet |
Genética humana Variacao genetica América |
description |
We examined genetic diversity and population structure in the American landmass using 678 autosomal microsatellite markers genotyped in 422 individuals representing 24 Native American populations sampled from North, Central, and South America. These data were analyzed jointly with similar data available in 54 other indigenous populations worldwide, including an additional five Native American groups. The Native American populations have lower genetic diversity and greater differentiation than populations from other continental regions. We observe gradients both of decreasing genetic diversity as a function of geographic distance from the Bering Strait and of decreasing genetic similarity to Siberians—signals of the southward dispersal of human populations from the northwestern tip of the Americas. We also observe evidence of: (1) a higher level of diversity and lower level of population structure in western South America compared to eastern South America, (2) a relative lack of differentiation between Mesoamerican and Andean populations, (3) a scenario in which coastal routes were easier for migrating peoples to traverse in comparison with inland routes, and (4) a partial agreement on a local scale between genetic similarity and the linguistic classification of populations. These findings offer new insights into the process of population dispersal and differentiation during the peopling of the Americas. |
format |
Article in Journal/Newspaper |
author |
Wang, Sijia Lewis Junior, Cecil M. Jakobsson, Mattias Ramachandran, Sohini Ray, Nicolas Bedoya, Gabriel Rojas, Winston Parra, María V. Molina, Julio A. Gallo, Carla Mazzotti, Guido Poletti, Giovanni Hill, Kim R. Hurtado, Ana Magdalena Labuda, Damian Klitz, William Barrantes, Ramiro Bortolini, Maria Cátira Salzano, Francisco Mauro Petzl-Erler, Maria Luiza Tsuneto, Luiza T. Llop, Elena Rothhammer, Francisco Excoffier, Laurent Feldman, Marcus W. Rosenberg, Noah A. Ruiz-Linares, Andres |
author_facet |
Wang, Sijia Lewis Junior, Cecil M. Jakobsson, Mattias Ramachandran, Sohini Ray, Nicolas Bedoya, Gabriel Rojas, Winston Parra, María V. Molina, Julio A. Gallo, Carla Mazzotti, Guido Poletti, Giovanni Hill, Kim R. Hurtado, Ana Magdalena Labuda, Damian Klitz, William Barrantes, Ramiro Bortolini, Maria Cátira Salzano, Francisco Mauro Petzl-Erler, Maria Luiza Tsuneto, Luiza T. Llop, Elena Rothhammer, Francisco Excoffier, Laurent Feldman, Marcus W. Rosenberg, Noah A. Ruiz-Linares, Andres |
author_sort |
Wang, Sijia |
title |
Genetic variation and population structure in native americans |
title_short |
Genetic variation and population structure in native americans |
title_full |
Genetic variation and population structure in native americans |
title_fullStr |
Genetic variation and population structure in native americans |
title_full_unstemmed |
Genetic variation and population structure in native americans |
title_sort |
genetic variation and population structure in native americans |
publishDate |
2008 |
url |
http://hdl.handle.net/10183/21545 |
geographic |
Bering Strait |
geographic_facet |
Bering Strait |
genre |
Bering Strait |
genre_facet |
Bering Strait |
op_relation |
Plos Genetics. Cambridge. Vol. 3, n. 11 (Nov. 2007), p. 2049-2067 |
op_rights |
Open Access |
_version_ |
1766378534541983744 |