Data_Sheet_1_Functional immune diversity in reindeer reveals a high Arctic population at risk.PDF
Climate changes the geographic range of both species as well as pathogens, causing a potential increase in the vulnerability of populations or species with limited genetic diversity. With advances in high throughput sequencing (HTS) technologies, we can now define functional expressed genetic divers...
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Online Access: | https://doi.org/10.3389/fevo.2022.1058674.s001 |
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ftunivfreestate:oai:figshare.com:article/21863484 2023-05-15T15:09:44+02:00 Data_Sheet_1_Functional immune diversity in reindeer reveals a high Arctic population at risk.PDF Morten Lukacs (7592) Ingebjørg H. Nymo (8161113) Knut Madslien (154596) Jørn Våge (5815760) Vebjørn Veiberg (3191850) Christer Moe Rolandsen (7852136) Cathrine Arnason Bøe (8591520) Arvind Y. M. Sundaram (6273509) Unni Grimholt (3286050) 2023-01-11T05:04:27Z https://doi.org/10.3389/fevo.2022.1058674.s001 unknown https://figshare.com/articles/dataset/Data_Sheet_1_Functional_immune_diversity_in_reindeer_reveals_a_high_Arctic_population_at_risk_PDF/21863484 doi:10.3389/fevo.2022.1058674.s001 CC BY 4.0 CC-BY Evolutionary Biology Ecology Invasive Species Ecology Landscape Ecology Conservation and Biodiversity Behavioural Ecology Community Ecology (excl. Invasive Species Ecology) Ecological Physiology Freshwater Ecology Marine and Estuarine Ecology (incl. Marine Ichthyology) Population Ecology Terrestrial Ecology climate change MHC reindeer immune diversity Svalbard Norway Dataset 2023 ftunivfreestate https://doi.org/10.3389/fevo.2022.1058674.s001 2023-01-13T00:36:51Z Climate changes the geographic range of both species as well as pathogens, causing a potential increase in the vulnerability of populations or species with limited genetic diversity. With advances in high throughput sequencing (HTS) technologies, we can now define functional expressed genetic diversity of wild species at a larger scale and identify populations at risk. Previous studies have used genomic DNA to define major histocompatibility complex (MHC) class II diversity in reindeer. Varying numbers of expressed genes found in many ungulates strongly argues for using cDNA in MHC typing strategies to ensure that diversity estimates relate to functional genes. We have used available reindeer genomes to identify candidate genes and established an HTS approach to define expressed MHC class I and class II diversity. To capture a broad diversity we included samples from wild reindeer from Southern Norway, semi-domesticated reindeer from Northern Norway and reindeer from the high Artic archipelago Svalbard. Our data show a medium MHC diversity in semi-domesticated and wild Norwegian mainland reindeer, and low MHC diversity reindeer in Svalbard reindeer. The low immune diversity in Svalbard reindeer provides a potential risk if the pathogenic pressure changes in response to altered environmental conditions due to climate change, or increased human-related activity. Dataset Arctic Arctic Population Climate change Northern Norway Svalbard svalbard reindeer KovsieScholar Repository (University of the Free State - UFS UV) Arctic Norway Svalbard |
institution |
Open Polar |
collection |
KovsieScholar Repository (University of the Free State - UFS UV) |
op_collection_id |
ftunivfreestate |
language |
unknown |
topic |
Evolutionary Biology Ecology Invasive Species Ecology Landscape Ecology Conservation and Biodiversity Behavioural Ecology Community Ecology (excl. Invasive Species Ecology) Ecological Physiology Freshwater Ecology Marine and Estuarine Ecology (incl. Marine Ichthyology) Population Ecology Terrestrial Ecology climate change MHC reindeer immune diversity Svalbard Norway |
spellingShingle |
Evolutionary Biology Ecology Invasive Species Ecology Landscape Ecology Conservation and Biodiversity Behavioural Ecology Community Ecology (excl. Invasive Species Ecology) Ecological Physiology Freshwater Ecology Marine and Estuarine Ecology (incl. Marine Ichthyology) Population Ecology Terrestrial Ecology climate change MHC reindeer immune diversity Svalbard Norway Morten Lukacs (7592) Ingebjørg H. Nymo (8161113) Knut Madslien (154596) Jørn Våge (5815760) Vebjørn Veiberg (3191850) Christer Moe Rolandsen (7852136) Cathrine Arnason Bøe (8591520) Arvind Y. M. Sundaram (6273509) Unni Grimholt (3286050) Data_Sheet_1_Functional immune diversity in reindeer reveals a high Arctic population at risk.PDF |
topic_facet |
Evolutionary Biology Ecology Invasive Species Ecology Landscape Ecology Conservation and Biodiversity Behavioural Ecology Community Ecology (excl. Invasive Species Ecology) Ecological Physiology Freshwater Ecology Marine and Estuarine Ecology (incl. Marine Ichthyology) Population Ecology Terrestrial Ecology climate change MHC reindeer immune diversity Svalbard Norway |
description |
Climate changes the geographic range of both species as well as pathogens, causing a potential increase in the vulnerability of populations or species with limited genetic diversity. With advances in high throughput sequencing (HTS) technologies, we can now define functional expressed genetic diversity of wild species at a larger scale and identify populations at risk. Previous studies have used genomic DNA to define major histocompatibility complex (MHC) class II diversity in reindeer. Varying numbers of expressed genes found in many ungulates strongly argues for using cDNA in MHC typing strategies to ensure that diversity estimates relate to functional genes. We have used available reindeer genomes to identify candidate genes and established an HTS approach to define expressed MHC class I and class II diversity. To capture a broad diversity we included samples from wild reindeer from Southern Norway, semi-domesticated reindeer from Northern Norway and reindeer from the high Artic archipelago Svalbard. Our data show a medium MHC diversity in semi-domesticated and wild Norwegian mainland reindeer, and low MHC diversity reindeer in Svalbard reindeer. The low immune diversity in Svalbard reindeer provides a potential risk if the pathogenic pressure changes in response to altered environmental conditions due to climate change, or increased human-related activity. |
format |
Dataset |
author |
Morten Lukacs (7592) Ingebjørg H. Nymo (8161113) Knut Madslien (154596) Jørn Våge (5815760) Vebjørn Veiberg (3191850) Christer Moe Rolandsen (7852136) Cathrine Arnason Bøe (8591520) Arvind Y. M. Sundaram (6273509) Unni Grimholt (3286050) |
author_facet |
Morten Lukacs (7592) Ingebjørg H. Nymo (8161113) Knut Madslien (154596) Jørn Våge (5815760) Vebjørn Veiberg (3191850) Christer Moe Rolandsen (7852136) Cathrine Arnason Bøe (8591520) Arvind Y. M. Sundaram (6273509) Unni Grimholt (3286050) |
author_sort |
Morten Lukacs (7592) |
title |
Data_Sheet_1_Functional immune diversity in reindeer reveals a high Arctic population at risk.PDF |
title_short |
Data_Sheet_1_Functional immune diversity in reindeer reveals a high Arctic population at risk.PDF |
title_full |
Data_Sheet_1_Functional immune diversity in reindeer reveals a high Arctic population at risk.PDF |
title_fullStr |
Data_Sheet_1_Functional immune diversity in reindeer reveals a high Arctic population at risk.PDF |
title_full_unstemmed |
Data_Sheet_1_Functional immune diversity in reindeer reveals a high Arctic population at risk.PDF |
title_sort |
data_sheet_1_functional immune diversity in reindeer reveals a high arctic population at risk.pdf |
publishDate |
2023 |
url |
https://doi.org/10.3389/fevo.2022.1058674.s001 |
geographic |
Arctic Norway Svalbard |
geographic_facet |
Arctic Norway Svalbard |
genre |
Arctic Arctic Population Climate change Northern Norway Svalbard svalbard reindeer |
genre_facet |
Arctic Arctic Population Climate change Northern Norway Svalbard svalbard reindeer |
op_relation |
https://figshare.com/articles/dataset/Data_Sheet_1_Functional_immune_diversity_in_reindeer_reveals_a_high_Arctic_population_at_risk_PDF/21863484 doi:10.3389/fevo.2022.1058674.s001 |
op_rights |
CC BY 4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.3389/fevo.2022.1058674.s001 |
_version_ |
1766340870861225984 |